公开(公告)号：UY32489A

公开(公告)日：2010-10-29

申请号：UY32489

申请日：2010-03-11

Applicant: UCB PHARMA SA

Inventor： NEIL GOZZARD ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  LIGHTWOOD DANIEL JOHN ,  PALFRAMAN ROGER THOMAS ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE

IPC: A61K39/395 ,  A61P43/00 ,  C07K16/00 ,  C07K16/24 ,  C12N15/79

Abstract: La invención se refiere a moléculas de anticuerpo que tienen especificidad por determinantes antigénicos de IL-13 humana, a usos terapéuticos de las moléculas de anticuerpo, y a métodos para producir dichas moléculas de anticuerpo

公开(公告)号：AU2003285578B2

公开(公告)日：2010-07-15

申请号：AU2003285578

申请日：2003-12-01

Applicant: UCB PHARMA SA

Inventor： CROMIE KAREN DOROTHY ,  GRIFFITHS MERYN RUTH ,  LIGHTWOOD DANIEL JOHN ,  BROWN DEREK THOMAS ,  BUTLER LISA ,  LAWSON ALASTAIR DAVID GRIFFITHS

IPC: C07K16/24 ,  G01N33/569 ,  G01N33/58 ,  G01N33/68

Abstract: The present invention provides a homogeneous assay for identifying an antibody producing cell producing an antibody which binds to a selected antigen comprising: a) providing a population of antibody producing cells; b) incubating said population of antibody producing cells with a selected antigen and a labeled anti-antibody antibody, wherein said anti-antibody antibody is capable of distinguishing cells producing an antibody which binds to the selected antigen from those cells which do not; and c) identifying an antibody producing cell capable of producing an antibody which binds to the selected antigen.

公开(公告)号：CA2656047A1

公开(公告)日：2008-01-10

申请号：CA2656047

申请日：2007-06-26

Applicant: UCB PHARMA SA

Inventor： POPPLEWELL ANDREW GEORGE ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  ADAMS RALPH ,  TYSON KERRY LOUISE

IPC: C07K16/46

Abstract: The present invention relates to improved methods for the selection of ap propriate human acceptor framework regions for non-human (donor) antibodies and methods for obtaining humanized antibodies of high affinity using such a cceptor frameworks.

公开(公告)号：CA2630652A1

公开(公告)日：2007-05-31

申请号：CA2630652

申请日：2006-11-21

Applicant: UCB PHARMA SA

Inventor： LAWSON ALASTAIR DAVID GRIFFITHS ,  FINNEY HELENE MARGARET

IPC: C12N15/63 ,  C07K14/705 ,  C12N5/16 ,  G01N33/566

Abstract: The invention relates to vectors encoding bioassay receptors and in vitro bioassays using said bioassay receptors for assessing compounds of interest. In particular, the bioassays provide a generic platform for the comparison o f binding of different ligands to their respective receptors or binding partne rs in the presence and/or absence of a compound of interest.

公开(公告)号：CA2778671C

公开(公告)日：2019-02-19

申请号：CA2778671

申请日：2010-10-27

Applicant: UCB PHARMA SA

Inventor： MILLER KAREN MARGRETE ,  DE RYCK MARC ROGER ,  WOLFF CHRISTIAN GILBERT J ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  FINNEY HELENE MARGARET ,  BAKER TERENCE SEWARD

IPC: C07K16/28

Abstract: An anti- E1 ion channel antibody or binding fragment thereof, pharmaceutical compositions comprising said antibodies, use of the antibodies and compositions comprising the same, in treatment, for example in the treatment/modulation of pain and processes for generating and preparing said antibodies.

公开(公告)号：SG10201510762YA

公开(公告)日：2016-01-28

申请号：SG10201510762Y

申请日：2012-01-11

Applicant: UCB PHARMA SA

Inventor： ADAMS RALPH ,  BAKER TERENCE SEWARD ,  LAWSON ALASTAIR DAVID GRIFFITHS

Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of both IL-17A and IL-17F, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

公开(公告)号：PE20150002A1

公开(公告)日：2015-01-28

申请号：PE2014001987

申请日：2013-05-13

Applicant: UCB PHARMA SA

Inventor： FINNEY HELENE MARGARET ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  SHAW STEVAN GRAHAM ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE ,  KEVORKIAN LARA ,  MEIER CHRISTOPH ,  SARKAR KAUSHIK ,  ATHERFOLD PAUL ALAN

IPC: G01N33/53 ,  C07K16/28

Abstract: SE REFIERE A UN ANTICUERPO O FRAGMENTO DE UNION DEL MISMO ANTI-FCRN QUE COMPRENDE: UNA CADENA PESADA QUE TIENE UNA REGION VARIABLE QUE COMPRENDE TRES CDR SELECCIONADAS INDEPENDIENTEMENTE DE SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3 ; Y UNA CADENA LIGERA QUE TIENE UNA REGION VARIABLE QUE COMPRENDE TRES CDR SELECCIONADAS INDEPENDIENTEMENTE DE SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA QUE ES UTIL PARA EL TRATAMIENTO DE ENFERMEDADES AUTOINMUNES.

公开(公告)号：AU2013298924A1

公开(公告)日：2015-01-15

申请号：AU2013298924

申请日：2013-05-13

Applicant: UCB PHARMA SA

Inventor： FINNEY HELENE MARGARET ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  SHAW STEVAN GRAHAM ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE ,  KEVORKIAN LARA ,  MEIER CHRISTOPH ,  SARKAR KAUSHIK ,  ATHERFOLD PAUL ALAN

IPC: C07K16/28 ,  G01N33/53

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：AU2010222693B2

公开(公告)日：2014-12-04

申请号：AU2010222693

申请日：2010-03-10

Applicant: UCB PHARMA SA

Inventor： GOZZARD NEIL ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  LIGHTWOOD DANIEL JOHN ,  PALFRAMAN ROGER THOMAS ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE

IPC: C07K16/24 ,  A61K39/395 ,  A61P11/06 ,  C07K16/46 ,  C12N15/13

Abstract: Antibody molecules having specificity for antigenic determinants of human IL-13, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

公开(公告)号：CL2013002044A1

公开(公告)日：2014-05-09

申请号：CL2013002044

申请日：2013-07-12

Applicant: UCB PHARMA SA

Inventor： ADAMS RALPH ,  BAKER TERENCE SEWARD ,  LAWSON ALASTAIR DAVID GRIFFITHS

IPC: C07K16/24 ,  A61K39/395 ,  A61P31/00 ,  C12N15/13