公开(公告)号：EP3370294A1

公开(公告)日：2018-09-05

申请号：EP17792399.2

申请日：2017-04-01

Applicant: Shenzhen Institutes of Advanced Technology

Inventor： TANG, Yongbing ,  SHENG, Maohua ,  ZHANG, Fan ,  JI, Bifa

IPC: H01M10/0525 ,  H01M10/058

CPC classification number: H01M10/0525 ,  H01M2/16 ,  H01M2/1613 ,  H01M2/1646 ,  H01M2/1653 ,  H01M4/134 ,  H01M4/1395 ,  H01M4/364 ,  H01M4/366 ,  H01M4/463 ,  H01M4/485 ,  H01M4/505 ,  H01M4/525 ,  H01M4/5825 ,  H01M4/625 ,  H01M4/661 ,  H01M4/662 ,  H01M4/663 ,  H01M4/667 ,  H01M4/80 ,  H01M10/0567 ,  H01M10/0568 ,  H01M10/0569 ,  H01M10/058 ,  H01M10/0585

Abstract: The present invention relates to the field of batteries, and more specifically to a secondary battery and a method for preparing the same. The secondary battery comprises a battery negative electrode, an electrolyte liquid, a diaphragm and a battery positive electrode, the battery negative electrode comprises a negative electrode current collector, and the negative electrode current collector also acts as a negative electrode active material; the electrolyte liquid comprises an electrolyte and a solvent, the electrolyte is a lithium salt; the battery positive electrode comprises a positive electrode current collector and a positive electrode active material layer, the positive electrode active material layer comprises a positive electrode active material capable of reversibly de-intercalating lithium ions. In the present invention, since a metal or metal alloy or metal composite is simultaneously used as the negative electrode current collector and the negative electrode active material, thus no additional negative electrode active material needs to be added, thereby effectively reducing the weight and volume of the battery; and in the meantime, the capacity of the battery is effectively increased. Further, the energy density of the battery is remarkably improved, the production cost is reduced, the production process is simplified, and the secondary battery of the present invention has a good charging and discharging cycle performance.

公开(公告)号：EP3031922A1

公开(公告)日：2016-06-15

申请号：EP14834580.4

申请日：2014-08-05

Applicant: Shenzhen Institutes of Advanced Technology ,  Shenzhen Hornetcorn Biotechnology Company, Ltd.

Inventor： CHEN, Zhiying ,  MA, Fei ,  HE, Chengyi

IPC: C12N15/85 ,  C12N15/66 ,  C12N15/11 ,  C12N15/10 ,  C07K16/18 ,  A61K39/395 ,  A61K48/00 ,  A61P35/00

CPC classification number: C12N15/64 ,  C12N15/10 ,  C12N15/70 ,  C12N15/85

Abstract: Provided are a minicircle DNA recombinant parental plasmid having a genetically engineered antibody gene expression cassette and a preparation method for the plasmid, a minicircle DNA having the genetically engineered antibody gene expression cassette, a preparation method for the DNA, and applications thereof, and, a host cell having the minicircle DNA, a preparation method for the cell, and applications thereof. Also provided are a genetically engineered antibody, a preparation method for same, and applications thereof.

Abstract translation: 提供了具有一个基因工程抗体基因的表达盒和用于该质粒的制备方法的小环DNA重组亲代质粒：具有基因工程抗体基因的表达盒，用于DNA制备方法一个小环DNA，及其应用，以及，一个 主机具有小环DNA，对于细胞的制备方法，以及它们的应用细胞。 所以提供的是遗传改造的抗体，其制备方法，以及它们的应用程序。

公开(公告)号：EP3614159A1

公开(公告)日：2020-02-26

申请号：EP18857442.0

申请日：2018-10-26

Applicant: Shenzhen Institutes of Advanced Technology

Inventor： ZHENG, Hairong ,  LI, Ye ,  CHEN, Qiaoyan ,  DU, Feng ,  LI, Nan ,  LI, Rou ,  LUO, Chao ,  HE, Quiang ,  OU, Hang ,  LIU, Xin

IPC: G01R33/34 ,  A61B5/055

Abstract: The present disclosure provides a dual-nuclear radio frequency (RF) coil device, including a first RF coil and a second RF coil. The first RF coil is a loop structure and includes at least one adjustment capacitor, the first RF coil is configured to generate a first magnetic field, and a direction of a primary magnetic field of the first magnetic field is a first direction. The second RF coil includes an electric dipole and a tuning and matching circuit connected between two conductors of the electric dipole. The second RF coil is configured to generate a second magnetic field and a direction of a primary magnetic field of the second magnetic field is a second direction; the electric dipole is disposed in a center line of the first RF coil and an insulating layer is disposed between the electric dipole and the first RF coil; and the first direction is perpendicular to the second direction. The present disclosure further provides a dual-nuclear RF coil array device.

公开(公告)号：EP3566655A1

公开(公告)日：2019-11-13

申请号：EP17934679.6

申请日：2017-12-26

Applicant: Shenzhen Institutes of Advanced Technology

Inventor： XIAO, Yang ,  ZHENG, Hairong ,  WANG, Congzhi ,  NIU, Lili ,  DENG, Zhiting

IPC: A61B8/08

Abstract: A method and a device for acquiring biomechanical parameters based on an ultrasonic elastomyogram are provided, wherein the method includes: synchronously collecting a dynamic myodynamics image sequence and a dynamic elasticity image sequence of a single skeletal muscle under continuous stretching; acquiring a myodynamics parameter corresponding to each myodynamics image in the dynamic myodynamics image sequence and an elasticity modulus value corresponding to each elasticity image in the dynamic elasticity image sequence respectively; and generating an ultrasonic elastomyogram curve with the myodynamics parameter as the abscissa and the synchronized elasticity modulus value as the ordinate, and estimating a muscle biomechanical parameter based on the ultrasonic elastomyogram curve. Dynamically changing biomechanical parameters can be obtained, and the obtained muscle biomechanical parameters have relatively high accuracy.

公开(公告)号：EP4064124B1

公开(公告)日：2025-05-07

申请号：EP19953002.3

申请日：2019-11-19

Inventor： WANG, Shuqiang ,  YU, Wen ,  SHEN, Yanyan ,  CHEN, Zhuo

IPC: G06V10/82 ,  G16H50/20 ,  G06N3/045 ,  G06N3/0464 ,  G06N3/0475 ,  G06N3/08 ,  G16H30/40

公开(公告)号：EP3521815B1

公开(公告)日：2024-07-03

申请号：EP17910501.0

申请日：2017-12-29

IPC: G01R33/56 ,  G01N24/08

CPC classification number: G01N24/08 ,  G01R33/5605 ,  G01R33/5608

公开(公告)号：EP3736595A1

公开(公告)日：2020-11-11

申请号：EP17932692.1

申请日：2017-11-27

Applicant: Shenzhen Institutes of Advanced Technology

Inventor： ZOU, Chao ,  CHENG, Chuanli ,  LIU, Xin ,  ZHENG, Hairong

IPC: G01R33/565

Abstract: An eddy-current correction method and apparatus, a mobile terminal and a readable storage medium. Said method comprises: step S1: reading gradient-recalled echo sequence by means of bipolarity, so as to acquire a multi-echo image; step S2: estimating a first-order term coefficient of an extra phase term introduced by an eddy-current in the acquired multi-echo image; step S3: removing the estimated first-order term coefficient, and estimating a zero-order term coefficient of the extra phase term introduced by the eddy-current in the collected multi-echo image; step S4: removing, according to the estimated first-order term coefficient and the zero-order term coefficient, an error of the extra phase term introduced by the eddy-current. The eddy-current correction method can remove the phase error caused by the eddy-current in the acquired image, thereby ensuring the correctness of the subsequent water-fat separation algorithm result.

公开(公告)号：EP3733853A1

公开(公告)日：2020-11-04

申请号：EP17936940.0

申请日：2017-12-29

Applicant: Shenzhen Institutes of Advanced Technology

Inventor： LIU, Chenli ,  LAI, Wangsheng ,  CHEN, Qian ,  WEI, Ting ,  SUN, Chenjian

IPC: C12N15/63 ,  C12N1/21

Abstract: This invention relates to the field of directed evolution and screening, and more particularly relates to a visual continuous spatial directed evolution method. The host grows and moves in a solid culture space, the host carrying a foreign target gene to be evolved and containing a gene element that assists the evolution of the target gene, the target gene being correlated with the growth and movement of the host. Depending on different spatial distribution patterns formed in the solid culture space during the growth and movement of the host, screening is performed to obtain an evolved product. This method is carried out directly in the solid culture space. Depending on images of different spatial distribution morphologies visible to the naked eye that are locally formed, selection of evolved products is performed without the need for liquid fed-batch culture equipment. In addition, the evolution effect is visually observed through the infection spots formed during evolution, so that no real-time monitoring equipment is required, making the method easy to operate and have a high throughput.

公开(公告)号：US20250148746A1

公开(公告)日：2025-05-08

申请号：US19019221

申请日：2025-01-13

Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES

Inventor： Hao PENG ,  Chao ZOU ,  Chuanli CHENG ,  Xin LIU ,  Hairong ZHENG

IPC: G06V10/25 ,  G06V10/26 ,  G06V10/36

Abstract: The present disclosure discloses a chemical shift coded imaging method based on a transition region and regional iterative phasor extraction. Acquiring an initial image, and determining an initial phasor solution of the transition region based on the initial image; performing regional iterative phasor extraction in at least two set directions by taking the initial phasor solution as initial information, and obtaining a target phasor solution based on a regional iterative phasor extraction result corresponding to each set direction; and determining a first chemical composition signal and a second chemical composition signal based on the target phasor solution, and performing chemical shift coded imaging based on the first chemical composition signal and/or the second chemical composition signal. By means of regional iterative phasor extraction in a plurality of dimensions, wrong phasor information is transferred independently along different dimensions, wrong information transferred in different directions is excluded.

公开(公告)号：US20250148574A1

公开(公告)日：2025-05-08

申请号：US19003261

申请日：2024-12-27

Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY

Inventor： Hongzhao CHEN ,  Tao SUN ,  Yaping WU ,  Zhenguo WANG ,  Meiyun WANG

IPC: G06T5/60 ,  G06T5/50 ,  G06T5/70

Abstract: The present disclosure discloses a method and apparatus for enhancing a PET parameter image, a device, and a storage medium. The method includes: obtaining, based on a preset mapping list, an input image corresponding to an original PET parameter image determined based on a dynamic PET image set; and inputting the input image into an image enhancement model, adjusting a model parameter of the image enhancement model based on the original PET parameter image and an output predicted PET parameter image until a preset number of iterations is met, and using the predicted PET parameter image as a target PET parameter image corresponding to the original PET parameter image; wherein the input image is a noise image, a dynamic PET image corresponding to a preset acquisition time range in the dynamic PET image set or a dynamic SUV image corresponding to the dynamic PET image.