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公开(公告)号：US08236553B2
公开(公告)日：2012-08-07
申请号：US12793253
申请日：2010-06-03
Applicant: Phillip Belgrader
Inventor： Phillip Belgrader
CPC classification number: G01N1/405 , B01D39/201 , B01L3/0275 , B01L3/502753 , B01L2200/0631 , B01L2300/0681 , C12N15/1017
Abstract: Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass frit.
Abstract translation: 提供了从含有这种核酸和外来物质的混合物中分离核酸的方法和装置。 在一个实施方案中，本发明的方法包括在有效将核酸与外来物质分离的条件下使混合物通过玻璃料。 在更具体的实施方案中，玻璃料是烧结玻璃料。
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32.发明授权公开(公告)号：US07053016B2
公开(公告)日：2006-05-30
申请号：US10308507
申请日：2002-12-03
Applicant: Takahiro Mizuno , Manabu Isomura , Tomonori Takahashi
Inventor： Takahiro Mizuno , Manabu Isomura , Tomonori Takahashi
IPC: C03C17/22
CPC classification number: C04B41/009 , B01D39/201 , B01D39/202 , C03C8/14 , C03C14/004 , C04B41/52 , C04B41/89 , C04B2111/00793 , C04B41/4535 , C04B41/5022 , C04B41/5027 , C04B41/5089 , C04B41/0072 , C04B41/4539 , C04B41/5031 , C04B35/10
Abstract: A ceramic porous body is provided which uses a binder made of a glass that has excellent acid resistance and alkali resistance and which can be used for a long period of time as a filtration filter. The ceramic porous body is formed from ceramic particles that are bonded using a glass binder comprising 5 to 20 mol % of a plurality of metal oxides, selected from the group consisting of Li2O, Na2O, K2O, MgO, CaO, SrO and BaO and containing at least two alkali metal oxides selected from the group consisting of Li2O, Na2O and K2O as an essential component, at least 3 mol % of at least one of ZrO2 and TiO2 as a total amount, and SiO2 and incidental impurities as the balance.
Abstract translation: 提供了一种陶瓷多孔体，其使用具有优异的耐酸性和耐碱性的玻璃制粘合剂，并且可以作为过滤器长时间使用。 陶瓷多孔体由使用包含5〜20摩尔％的多种金属氧化物的玻璃粘合剂结合的陶瓷颗粒形成，所述金属氧化物选自Li 2 O 2，Na 2 O， 2 O，K 2 O，MgO，CaO，SrO和BaO，并且含有至少两种选自Li 2 O， 作为必要成分的Na 2 O 2和K 2 O 2，至少3摩尔％的ZrO 2和TiO 2的至少一种， 作为总量的SiO 2和偶氮杂质作为余量。
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公开(公告)号：US20050218057A1
公开(公告)日：2005-10-06
申请号：US10969832
申请日：2004-10-21
Applicant: Lee Ngee
Inventor： Lee Ngee
IPC: B01D25/12 , B01D25/164 , B01D25/176 , B01D25/21 , B01D39/20
CPC classification number: B01D39/2034 , B01D25/164 , B01D25/21 , B01D39/16 , B01D39/201 , B01D39/2075
Abstract: A filter plate assembly includes a base body, a filter media and a frame. The filter plate assembly can be used in a filter press. The filter media is mounted in either side the base body and is held in place by a frame mounted in face to face contact with the filter media. The filter media is a rigid or semi-rigid structure made from sintered material. The filter sintered material can be a polymer, metal, glass, or a ceramic, and the polymer can be polyvinylchloride (PVC), polyethylene (PE), polyurethane (PU), polyvinyldifluoride (PVDF), polytetrafluro-ethylene (PTFE), or polypropylene (PP).
Abstract translation: 过滤板组件包括基体，过滤介质和框架。 过滤板组件可用于压滤机中。 过滤介质安装在基体的任一侧，并通过与过滤介质面对面接触安装的框架保持在适当的位置。 过滤介质是由烧结材料制成的刚性或半刚性结构。 过滤烧结材料可以是聚合物，金属，玻璃或陶瓷，聚合物可以是聚氯乙烯（PVC），聚乙烯（PE），聚氨酯（PU），聚偏二氟乙烯（PVDF），聚四氟乙烯（PTFE）或 聚丙烯（PP）。
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公开(公告)号：US20040071612A1
公开(公告)日：2004-04-15
申请号：US10261268
申请日：2002-09-30
Inventor： Mary W. Colby , Andre E. Berghmans , Donald DiMarzio , Ronald Pirich
IPC: B01D053/00 , B01J019/08 , B01J019/12
CPC classification number: B01D39/201 , A61L9/00 , B01D53/8687 , B01D53/885 , B01D2255/802 , F24F3/1603 , F24F2003/1667
Abstract: A microbicidal filter system having superior drop pressure and low complexity is provided, as well as a method for producing the same. The system comprises a plurality of glass beads having pores formed therebetween for the flow of air therethrough. The sintered glass beads are coated in a transition metal oxide and water. An ultraviolet light source is used to cause a photocatalytic reaction between the transition metal oxide and water. Free hydroxyl radicals with microbicidal properties are produced. Urethane foam may be inserted between the glass beads before sintering in order to cause a bimodal pore size distribution, and particulates disposed on the glass beads may be added to alter surface activity.
Abstract translation: 提供了具有优异的降压和低复杂性的杀菌过滤系统及其制造方法。 该系统包括多个玻璃珠，其间形成有用于使空气流过其中的孔。 将烧结的玻璃珠涂覆在过渡金属氧化物和水中。 使用紫外光源引起过渡金属氧化物和水之间的光催化反应。 产生具有杀菌特性的游离羟基。 在烧结之前，可以在玻璃珠之间插入聚氨酯泡沫，以引起双峰孔径分布，并且可以加入设置在玻璃珠上的颗粒以改变表面活性。
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公开(公告)号：US5457044A
公开(公告)日：1995-10-10
申请号：US145922
申请日：1993-10-29
Applicant: David C. Cipolla , Igor Gonda
Inventor： David C. Cipolla , Igor Gonda
CPC classification number: C12N9/22 , B01D39/201 , C07K1/34
Abstract: A method for collecting an aerosolized therapeutic polypeptide of interest, such as recombinant human deoxyribonuclease I (rhDNase), is provided which enables a determination as to the effect aerosolization has on the activity and integrity of the polypeptide. An aerosol of the polypeptide is generated using a nebulizer, for example, and the polypeptide is collected in an inert filter, such as a sintered glass filter. To increase the amount of polypeptide collected, the aerosol is preferably mixed with pre-humidified dilution air at a temperature between about 40.degree. and 55.degree. C. The collected polypeptide is subjected to biochemical activity and integrity analysis compared to the activity and integrity of the control polypeptide which has not been aerosolized.
Abstract translation: 提供了一种用于收集目的地雾化的治疗性多肽的方法，例如重组人脱氧核糖核酸酶I（rhDNase），其使得能够确定雾化对多肽的活性和完整性的影响。 例如，使用喷雾器产生多肽的气溶胶，并将多肽收集在惰性过滤器如烧结玻璃过滤器中。 为了增加收集的多肽的量，气雾剂优选在约40℃至55℃的温度下与预加湿的稀释空气混合。收集的多肽与生物化学活性和完整性分析相比，其活性和完整性 对照多肽尚未雾化。
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Patent Agency Ranking
公开(公告)号：US20120183799A1
公开(公告)日：2012-07-19
申请号：US13364478
申请日：2012-02-02
Applicant: James K. Steele , Wayne F. White , Alfred M. Romano , Kenneth L. Rubow
Inventor： James K. Steele , Wayne F. White , Alfred M. Romano , Kenneth L. Rubow
CPC classification number: B01D39/201 , B01D39/2027 , B01D39/2034 , B01D2239/0258 , B01D2239/0478 , B01D2239/0654 , B01D2239/083 , B01D2239/10 , B01D2239/1216 , B01D2239/1241 , B01J2/006 , B01J2/04 , B01J2/18 , B01J23/42 , B01J35/04 , B22F1/0018 , B22F3/1103 , B22F5/106 , B22F7/002 , B22F7/02 , B82Y30/00 , C22C1/02 , C22C5/04 , C22C14/00 , C22C19/056 , C22C38/00 , C23C18/06 , C23C24/04 , C23C24/08 , Y10T428/12042 , Y10T428/12479 , Y10T428/13 , Y10T428/249981
Abstract: A composite structure includes a substrate with pores of a first mean pore size and a coating on at least one surface of that substrate. This coating has pores of a second mean pore size where the first mean pore size is equal to or greater than said second mean pore size. When the pore size of the coating is effective to capture particulate greater than 0.2 micron, the composite may be formed into a filter effective to remove microbes from a fluid medium. One method to form the porous coating on the substrate includes: (1) forming a suspension of sinterable particles in a carrier fluid and containing the suspension in a reservoir; (2) maintaining the suspension by agitation; (3) transferring the suspension to an ultrasonic spray nozzle; (4) applying a first coating of the suspension to the substrate; and (5) sintering the sinterable particles to the substrate.
Abstract translation: 复合结构包括具有第一平均孔径的孔和在该基底的至少一个表面上的涂层的基底。 该涂层具有第二平均孔径的孔，其中第一平均孔径等于或大于所述第二平均孔径。 当涂层的孔径有效捕获大于0.2微米的颗粒时，复合材料可形成有效去除流体介质中微生物的过滤器。 在基材上形成多孔涂层的一种方法包括：（1）在载体流体中形成可烧结颗粒的悬浮液并将其悬浮液储存在容器中; （2）搅拌保持悬浮液; （3）将悬架转移到超声波喷嘴; （4）将所述悬浮液的第一涂层施加到所述基材上; 和（5）将可烧结颗粒烧结到基材上。
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公开(公告)号：US20100240123A1
公开(公告)日：2010-09-23
申请号：US12793253
申请日：2010-06-03
Applicant: Phillip Belgrader
Inventor： Phillip Belgrader
CPC classification number: G01N1/405 , B01D39/201 , B01L3/0275 , B01L3/502753 , B01L2200/0631 , B01L2300/0681 , C12N15/1017
Abstract: Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass frit.
Abstract translation: 提供了从含有这种核酸和外来物质的混合物中分离核酸的方法和装置。 在一个实施方案中，本发明的方法包括在有效将核酸与外来物质分离的条件下使混合物通过玻璃料。 在更具体的实施方案中，玻璃料是烧结玻璃料。
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公开(公告)号：US07759112B2
公开(公告)日：2010-07-20
申请号：US11933113
申请日：2007-10-31
Applicant: Philip Belgrader
Inventor： Philip Belgrader
CPC classification number: G01N1/405 , B01D39/201 , B01L3/0275 , B01L3/502753 , B01L2200/0631 , B01L2300/0681 , C12N15/1017
Abstract: Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass frit.
Abstract translation: 提供了从含有这种核酸和外来物质的混合物中分离核酸的方法和装置。 在一个实施方案中，本发明的方法包括在有效将核酸与外来物质分离的条件下使混合物通过玻璃料。 在更具体的实施方案中，玻璃料是烧结玻璃料。
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公开(公告)号：US20090107927A1
公开(公告)日：2009-04-30
申请号：US11933113
申请日：2007-10-31
Applicant: Philip Belgrader
Inventor： Philip Belgrader
CPC classification number: G01N1/405 , B01D39/201 , B01L3/0275 , B01L3/502753 , B01L2200/0631 , B01L2300/0681 , C12N15/1017
Abstract: Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass frit.
Abstract translation: 提供了从含有这种核酸和外来物质的混合物中分离核酸的方法和装置。 在一个实施方案中，本发明的方法包括在有效将核酸与外来物质分离的条件下使混合物通过玻璃料。 在更具体的实施方案中，玻璃料是烧结玻璃料。
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公开(公告)号：US06783740B2
公开(公告)日：2004-08-31
申请号：US10261268
申请日：2002-09-30
Applicant: Mary W. Colby , Andre E. Berghmans , Donald DiMarzio , Ronald Pirich
Inventor： Mary W. Colby , Andre E. Berghmans , Donald DiMarzio , Ronald Pirich
IPC: B01J1908
CPC classification number: B01D39/201 , A61L9/00 , B01D53/8687 , B01D53/885 , B01D2255/802 , F24F3/1603 , F24F2003/1667
Abstract: A microbicidal filter system having superior drop pressure and low complexity is provided, as well as a method for producing the same. The system comprises a plurality of glass beads having pores formed therebetween for the flow of air therethrough. The sintered glass beads are coated in a transition metal oxide and water. An ultraviolet light source is used to cause a photocatalytic reaction between the transition metal oxide and water. Free hydroxyl radicals with microbicidal properties are produced. Urethane foam may be inserted between the glass beads before sintering in order to cause a bimodal pore size distribution, and particulates disposed on the glass beads may be added to alter surface activity.
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