公开(公告)号：KR1020110134641A

公开(公告)日：2011-12-15

申请号：KR1020100054327

申请日：2010-06-09

Applicant: 주식회사한국신약

Inventor： 성연희 ,  배기환 ,  유재국

IPC: A61K36/9066 ,  A61K36/06 ,  A61K36/539 ,  A61P25/00

CPC classification number: A61K36/9066 ,  A23V2200/322 ,  A61K36/07 ,  A61K36/539 ,  A61K2236/331 ,  A61K2236/333

Abstract: PURPOSE: A composition containing Curcuma Longae Radix, Phellinus Linteus, and Scutellariae Radix is provided to suppress Ca^2+ and reactive oxygen generation. CONSTITUTION: A pharmaceutical composition for preventing or treating cerebrovascular diseases contains extract of Curcuma Longae Radix, Phellinus Linteus, and Scutellariae Radix as an active ingredient. The extract is isolated using water, alcohol, or mixture thereof. The alcohol is C1-C4 low alcohol. A neutraceutical food for preventing and treating cerebrovascular diseases contains Curcuma Longae Radix, Phellinus Linteus, and Scutellariae Radix as an active ingredient.

Abstract translation: 目的：提供含有姜黄龙藿，黄芩和黄芩的组合物，以抑制Ca 2+和活性氧的产生。 构成：用于预防或治疗脑血管疾病的药物组合物含有姜黄黄芩，黄芩，黄芩提取物作为活性成分。 使用水，醇或其混合物分离提取物。 酒精是C1-C4低酒精。 一种用于预防和治疗脑血管疾病的中性食品，含有姜黄，龙胆，黄芩和黄芩作为活性成分。

公开(公告)号：KR1020100079269A

公开(公告)日：2010-07-08

申请号：KR1020080137698

申请日：2008-12-31

Applicant: 주식회사한국신약

Inventor： 배기환 ,  김문일 ,  유재국 ,  박병욱 ,  김진표 ,  이익수

IPC: A23L1/30 ,  A23L1/28 ,  A61K36/06 ,  A61P35/00

CPC classification number: A23L33/105 ,  A23L5/00 ,  A23L31/00 ,  A23L33/10

Abstract: PURPOSE: Anticancer health food including fermented ginseng and mushroom powder is provided to maximize anticancer effects of ginseng and mushroom fungus, and to improve beneficial components of ginseng by fermenting the ginseng and mushroom fungus. CONSTITUTION: A manufacturing method of anticancer health food including fermented ginseng and mushroom powder includes the following steps: drying the ginseng; sterilizing the dried ginseng; making fermented materials by fermenting the sterilized ginseng in 20~30°C for 30 ~ 60 days; and pulverizing the fermented materials. The ginseng is fresh ginseng, white ginseng, straight ginseng, half-curved ginseng, curved ginseng, unpeeled white ginseng, red ginseng, first grade red ginseng, second grade red ginseng, third grade ginseng, lowest grade red ginseng, taeguk ginseng, ginseng root hair, or undried ginseng root hair.

Abstract translation: 目的：提供发酵人参和蘑菇粉等抗癌保健食品，以最大限度地发挥人参和蘑菇真菌的抗癌作用，通过发酵人参和蘑菇真菌来改善人参的有益成分。 构成：包括发酵人参和蘑菇粉在内的抗癌保健食品的制造方法，包括以下步骤：干燥人参; 灭干人参; 通过将灭菌的人参在20〜30℃下发酵30〜60天，制成发酵物质; 并粉碎发酵材料。 人参是人参，白参，直参，半曲参，人参参，白皮参，红参，一级红参，二级红参，三级人参，最低级红参，泰参人参，人参 根毛，或未干燥的人参根毛。

公开(公告)号：KR1020080065085A

公开(公告)日：2008-07-11

申请号：KR1020070002037

申请日：2007-01-08

Applicant: 주식회사한국신약

Inventor： 김진표 ,  서정주 ,  백진아 ,  유재국

IPC: C12P19/00 ,  A61K31/185 ,  A61K31/16

CPC classification number: A61K31/197 ,  A61K31/715 ,  C12P19/04

Abstract: A mixture composition comprising a polysaccharide extracted from phellinus linteus hypha and theanine is provided to promote immunoreaction by promoting differentiation of immune cells and antibody formation capability and be usefully used for preventing and treating immune-related diseases such as cancer. A mixture composition comprises a polysaccharide extracted from phellinus linteus hypha and theanine. An immuno-enhancing agent or an agent for inhibiting cell proliferative diseases such as cancer comprises the mixture composition.

Abstract translation: 提供了包含从桑黄和茶氨酸提取的多糖的混合物组合物，以通过促进免疫细胞分化和抗体形成能力来促进免疫反应，并且有效地用于预防和治疗免疫相关疾病如癌症。 混合物组合物包含从桑黄菌丝和茶氨酸提取的多糖。 免疫增强剂或抑制细胞增殖性疾病如癌症的药剂包括混合物组合物。

公开(公告)号：KR100592129B1

公开(公告)日：2006-06-23

申请号：KR1020040039112

申请日：2004-05-31

Applicant: 주식회사한국신약

Inventor： 김환철 ,  서승보 ,  최창하 ,  이찬복 ,  김진표 ,  김동희 ,  조수묵 ,  유창현 ,  유재국

IPC: A01G1/04 ,  C12N1/14 ,  A61K36/06

Abstract: 본 발명은 차가버섯 균사체의 대량생산을 위한 액체배양법에 관한 것으로서, 구체적으로 뽕나무 추출물이 첨가된 한천배지를 이용하여 차가버섯 균사체를 초기 고체 종배양하고, 상기 고체 종배양한 균사체를 균질화하여 액체 종배양한 후, 이를 대량생산을 위하여 회분식 액체 배양하는 방법에 관한 것이다. 본 발명의 차가버섯 균사체의 액체배양법은 기존의 자실체를 채집하거나 재배하는 방법을 이용할 때 따르는 자원고갈이나 생태계 파괴 등의 문제점을 해결하고, 재배기간을 단축시킬 수 있는 저비용의 고품질 다수확이 가능한 진보적인 배양방법으로 산업적으로 유용하게 이용될 수 있다.
차가버섯(Inonotus Obliquus)

公开(公告)号：KR100520995B1

公开(公告)日：2005-10-12

申请号：KR1020020024941

申请日：2002-05-07

Applicant: 주식회사한국신약 ,  주식회사 한생화장품

Inventor： 나민균 ,  민동일 ,  전영민 ,  이찬복 ,  김진표 ,  유재국

IPC: A61K8/97 ,  A61Q19/08

Abstract: 본 발명은 세포에 대한 노화 억제 작용을 하는 가자 추출물 및 이를 유효성분으로 함유하는 세포 노화 억제용 화장품 및 식품첨가물에 관한 것으로서, 본 발명의 가자 추출물은 강한 항산화활성 및 산화적 스트레스에 대한 세포보호 작용을 나타내며, 텔로미어 길이의 단축을 억제하여 피부세포의 노화 억제에 효과적이므로, 피부노화 방지 효과를 나타내는 화장품 및 식품 첨가물 등에 유용하게 사용될 수 있다.

公开(公告)号：KR1020050079229A

公开(公告)日：2005-08-09

申请号：KR1020050056189

申请日：2005-06-28

Applicant: 주식회사한국신약

Inventor： 홍남두 ,  조수묵 ,  유재국

IPC: A23L2/38

CPC classification number: A23V2002/00 ,  A23V2200/334 ,  A23L33/40 ,  A23L33/00 ,  A23L33/30

Abstract: 본 발명은 아스타잔틴(astaxanthin) 및 아스파라긴산(aspartic acid)을 유효성분으로 함유하는 숙취해소제에 관한 것이다. 본 발명의 숙취해소제는 음주 후 혈중 알코올 농도를 감소시킬 뿐만 아니라 숙취 해소에 뛰어난 효과가 있으므로, 이를 음료나 식품 등의 기능성식품 및 건강보조식품에 사용될 수 있다.

公开(公告)号：KR100455906B1

公开(公告)日：2004-11-15

申请号：KR1020010066256

申请日：2001-10-26

Applicant: 주식회사한국신약

Inventor： 홍남두 ,  이찬복 ,  배은아 ,  김동현 ,  조수묵 ,  유재국

IPC: A61K31/716

Abstract: PURPOSE: A composition containing as an active ingredient, α(1,6)-heteroglycan and galactomannoglucan is provided. The composition selectively exhibits cytotoxicity to lung cancer cells and is thus used as a pharmaceutical composition for the treatment of lung cancer. CONSTITUTION: The pharmaceutical composition contains α(1,6)-heteroglycan and galactomannoglucan having a molecular weight of 153,000 daltons as immunologically active polysaccharides. The α(1,6)-heteroglycan(Mesima) and galactomannoglucan(Mesima PL-2) are obtained by extracting and purifying the mycelium of Phellinus linteus(KCTC 0173BP) and (KCTC 0399BP). The effective dose of the Mesima and Mesima PL-2 is 10 to 25mg/kg.

Abstract translation: 目的：提供含有α（1,6） - 聚葡聚糖和半乳甘露糖葡聚糖作为活性成分的组合物。 该组合物选择性地表现出对肺癌细胞的细胞毒性，因此用作治疗肺癌的药物组合物。 构成：药物组合物含有分子量为153,000道尔顿的α（1,6） - 杂聚糖和半乳甘露糖葡聚糖作为免疫活性多糖。 通过提取和纯化桑黄的菌丝体（KCTC 0173BP）和（KCTC 0399BP）获得α（1,6） - 聚葡聚糖（Mesima）和半乳甘露糖葡聚糖（Mesima PL-2）。 Mesima和Mesima PL-2的有效剂量为10至25mg / kg。

公开(公告)号：KR1020040087809A

公开(公告)日：2004-10-15

申请号：KR1020030022745

申请日：2003-04-10

Applicant: 주식회사한국신약

Inventor： 홍남두 ,  조수묵 ,  유재국

IPC: A61K31/198

CPC classification number: A23L29/035 ,  A23L19/00 ,  A23L29/045 ,  A23L31/15 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/334

Abstract: PURPOSE: Provided is a hangover curing agent containing astaxanthin, aspartic acid and the extract of arrowroot flowers as an active ingredient. The agent reduces blood alcohol concentration and displays excellent hangover removal effect. CONSTITUTION: The hangover curing agent is characterized by containing 0.01-0.1 wt.% of astaxanthin, 1-5 wt.% of aspartic acid and 1-5 wt.% of the extract of arrowroot flowers as active ingredient. An oral preparation containing the agent is formulated into pills, granules, powder, capsules and liquid.

Abstract translation: 目的：提供含有虾青素，天冬氨酸和竹根花提取物作为活性成分的宿醉固化剂。 该药降低血液酒精浓度，显示出优异的宿醉去除效果。 构成：宿醉固化剂的特征在于含有0.01-0.1重量％的虾青素，1-5重量％的天冬氨酸和1-5重量％的作为活性成分的arrow根提取物。 将含有该药剂的口服制剂配制成丸剂，颗粒剂，粉剂，胶囊剂和液体剂。

公开(公告)号：KR1020040087808A

公开(公告)日：2004-10-15

申请号：KR1020030022744

申请日：2003-04-10

Applicant: 주식회사한국신약

Inventor： 홍남두 ,  조수묵 ,  유재국

IPC: A61K31/122

CPC classification number: A23L29/035 ,  A23L29/045 ,  A23L31/15 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/334

Abstract: PURPOSE: Provided is a hangover curing agent containing astaxanthin and aspartic acid as active ingredient. The agent reduces blood alcohol concentration as well as has hangover removal effect. CONSTITUTION: The hangover curing agent is characterized by containing 0.01-0.1 wt.% of astaxanthin as active ingredient. It additionally contains 1-5 wt.% of aspartic acid. An oral preparation containing the agent is formulated into pills, granules, powder, capsules and liquid.

Abstract translation: 目的：提供含有虾青素和天冬氨酸作为活性成分的宿醉固化剂。 该药降低血液酒精浓度，具有脱毒效果。 构成：宿醉固化剂的特征在于含有0.01-0.1重量％的虾青素作为活性成分。 另外还含有1-5％（重量）的天冬氨酸。 将含有该试剂的口服制剂配制成丸剂，颗粒剂，粉剂，胶囊剂和液体剂。

公开(公告)号：KR1020040082160A

公开(公告)日：2004-09-24

申请号：KR1020030016836

申请日：2003-03-18

Applicant: 주식회사한국신약

Inventor： 홍남두 ,  김민영 ,  박병영 ,  조수묵 ,  유재국 ,  이찬복 ,  김진표

IPC: A61K31/715 ,  A61K31/716 ,  A61K8/97 ,  A61P9/14

CPC classification number: A61K36/07 ,  A61K9/0053 ,  A61K31/716 ,  A61K2236/331 ,  Y10S514/866

Abstract: PURPOSE: A pharmaceutical composition containing polysaccharide such as galactomannoglucan extracted from the mycelium of Phellinus linteus as an effective ingredient is provided. The composition can be used for treatment of arthritis, diabetic retinopathy, psoriasis, cancer or the like. CONSTITUTION: The pharmaceutical composition for prevention and treatment of diseases associated with angiogenesis contains 80 to 95% by weight of galactomannoglucan as an effective ingredient. The galactomannoglucan is obtained from the mycelium of Phellinus linteus. The effective amount of the pharmaceutical composition is 50 to 80mg/kg, preferably 55 to 65mg/kg and can be administered 1 to 3 times per day. The disease associated with angiogenesis is arthritis, proriasis, cancer and ophthalmic disease selected from diabetic retinopathy, macular degeneration, retinopathy of prematurity and neovascular glaucoma.

Abstract translation: 目的：提供一种含有从桑黄菌丝体提取的多糖如半乳甘露聚葡聚糖作为有效成分的药物组合物。 该组合物可用于治疗关节炎，糖尿病性视网膜病，牛皮癣，癌症等。 构成：用于预防和治疗与血管生成相关的疾病的药物组合物含有80至95重量％的半乳糖葡聚糖作为有效成分。 半乳甘露聚糖从桑黄的菌丝体获得。 药物组合物的有效量为50〜80mg / kg，优选为55〜65mg / kg，每日可施用1〜3次。 与血管发生相关的疾病是选自糖尿病性视网膜病变，黄斑变性，早产儿视网膜病变和新生血管性青光眼的关节炎，分裂症，癌症和眼科疾病。