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1.发明公开펠리누스 린테우스의 균사체를 추출 정제하여 얻은다당류를 유효성분으로 포함하는 폐암 치료용 약학적 조성물 有权用于治疗肺癌的药物组合物，其作为通过提取和纯化PHELLINUS LINTEUS的MYCELI获得的活性成分多糖
公开(公告)号：KR1020030034604A
公开(公告)日：2003-05-09
申请号：KR1020010066256
申请日：2001-10-26
Applicant: 주식회사한국신약
IPC: A61K31/716
Abstract: PURPOSE: A composition containing as an active ingredient, α(1,6)-heteroglycan and galactomannoglucan is provided. The composition selectively exhibits cytotoxicity to lung cancer cells and is thus used as a pharmaceutical composition for the treatment of lung cancer. CONSTITUTION: The pharmaceutical composition contains α(1,6)-heteroglycan and galactomannoglucan having a molecular weight of 153,000 daltons as immunologically active polysaccharides. The α(1,6)-heteroglycan(Mesima) and galactomannoglucan(Mesima PL-2) are obtained by extracting and purifying the mycelium of Phellinus linteus(KCTC 0173BP) and (KCTC 0399BP). The effective dose of the Mesima and Mesima PL-2 is 10 to 25mg/kg.
Abstract translation: 目的：提供含有作为活性成分的α（1,6） - 异葡聚糖和半乳糖葡聚糖的组合物。 该组合物选择性地显示对肺癌细胞的细胞毒性，因此用作治疗肺癌的药物组合物。 构成：药物组合物含有分子量为153,000道尔顿的α（1,6） - 异葡聚糖和半乳糖葡聚糖作为免疫活性多糖。 通过提取和纯化桑黄的菌丝体（KCTC 0173BP）和（KCTC 0399BP）获得α（1,6） - 杂聚糖（Mesima）和半乳糖葡聚糖（Mesima PL-2）。 Mesima和Mesima PL-2的有效剂量为10〜25mg / kg。
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2.发明授权펠리누스 린테우스의 균사체를 추출 정제하여 얻은다당류를 유효성분으로 포함하는 폐암 치료용 약학적 조성물 有权펠리누스린테우스의균사체를추출정제하여얻은다당류를유효성분으로포함하는폐암치료용약학치조성물
公开(公告)号：KR100455906B1
公开(公告)日：2004-11-15
申请号：KR1020010066256
申请日：2001-10-26
Applicant: 주식회사한국신약
IPC: A61K31/716
Abstract: PURPOSE: A composition containing as an active ingredient, α(1,6)-heteroglycan and galactomannoglucan is provided. The composition selectively exhibits cytotoxicity to lung cancer cells and is thus used as a pharmaceutical composition for the treatment of lung cancer. CONSTITUTION: The pharmaceutical composition contains α(1,6)-heteroglycan and galactomannoglucan having a molecular weight of 153,000 daltons as immunologically active polysaccharides. The α(1,6)-heteroglycan(Mesima) and galactomannoglucan(Mesima PL-2) are obtained by extracting and purifying the mycelium of Phellinus linteus(KCTC 0173BP) and (KCTC 0399BP). The effective dose of the Mesima and Mesima PL-2 is 10 to 25mg/kg.
Abstract translation: 目的：提供含有α（1,6） - 聚葡聚糖和半乳甘露糖葡聚糖作为活性成分的组合物。 该组合物选择性地表现出对肺癌细胞的细胞毒性，因此用作治疗肺癌的药物组合物。 构成：药物组合物含有分子量为153,000道尔顿的α（1,6） - 杂聚糖和半乳甘露糖葡聚糖作为免疫活性多糖。 通过提取和纯化桑黄的菌丝体（KCTC 0173BP）和（KCTC 0399BP）获得α（1,6） - 聚葡聚糖（Mesima）和半乳甘露糖葡聚糖（Mesima PL-2）。 Mesima和Mesima PL-2的有效剂量为10至25mg / kg。
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