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公开(公告)号:US11046818B2
公开(公告)日:2021-06-29
申请号:US15513780
申请日:2015-10-13
Applicant: Ferrosan Medical Devices A/S
Inventor: Kristian Larsen , Flemming Reissig Jensen , Michael Wrang Mortensen
Abstract: The present disclosure relates to a dry composition which reconstitutes without mechanical mixing to form a flowable paste having a soft and light consistency suitable for use in haemostasis and wound healing procedures upon addition of an aqueous medium. The disclosure further relates to methods of preparing the dry composition, methods for reconstituting the dry composition and medical use of the composition.
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公开(公告)号:US10960179B2
公开(公告)日:2021-03-30
申请号:US14488840
申请日:2014-09-17
Applicant: Ferrosan Medical Devices, A/S
Inventor: Flemming Reissig Jensen , Bettina Metzler , Martin Bue Bertelsen , Rasmus Kaastrup Torekov
Abstract: An applicator device for applying an agent to a target site with a malleable tip that can be cut to length with a pair of nursing dressing scissors or similar type of scissors and a malleable tip with a formable tube that that can be cut to length with a pair of nursing dressing scissors or similar type of scissors. The malleable tip is configured for passage of fluid therethrough and includes a malleable member. The malleable member is made of a soft metal that is strong enough to retain the shape of the tip after is has been bend into configuration, but soft and weak enough to be easily cut with a pair of nursing dressing scissors or the like.
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公开(公告)号:US10595837B2
公开(公告)日:2020-03-24
申请号:US15639237
申请日:2017-06-30
Applicant: Ferrosan Medical Devices A/S
Inventor: Kristian Larsen , Michael Wrang Mortensen
Abstract: The present disclosure relates to a method for vacuum expansion of a paste prior to freeze-drying said paste to achieve a dry paste composition which reconstitutes efficiently to form a flowable paste upon addition of an aqueous medium. The present disclosure further relates to a syringe for retaining a dry paste composition in a vacuum.
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公开(公告)号:US10111980B2
公开(公告)日:2018-10-30
申请号:US15102994
申请日:2014-12-10
Applicant: Ferrosan Medical Devices A/S
Inventor: Kristian Larsen
Abstract: Disclosed is a dry composition comprising one or more polyols, which upon addition of an aqueous medium forms a substantially homogenous paste suitable for use in haemostasis procedures. The paste reconstitutes spontaneously upon addition of the liquid; hence no mechanical mixing is required for said paste to form. The composition may further comprise an extrusion enhancer, such as albumin. Also disclosed are methods of preparing said dry composition, a paste obtained from said dry composition and uses of said dry composition or paste for medical and surgical purposes.
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公开(公告)号:US20180296753A1
公开(公告)日:2018-10-18
申请号:US15517674
申请日:2015-10-28
Applicant: Ferrosan Medical Devices A/S
Inventor: Kai Lange , Christian Rothe , Frederik Sonnenborg , Arnt Larsen Lund , Søren Falkesgaard Ørts , Claus Reuber
IPC: A61M5/142 , A61K31/167 , A61K31/445 , A61M5/145 , A61K9/00
Abstract: The present disclosure relates to administration of fluid medication, in particular medication and dosing regimen for management of pain, more specifically to an anesthetic and dosing regimen for anesthetic for perioperative pain management and/or for palliative care. The present disclosure relates further to a medication pump and a method for delivering medication using the medication pump.
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公开(公告)号:US20180243468A1
公开(公告)日:2018-08-30
申请号:US15963795
申请日:2018-04-26
Applicant: Ferrosan Medical Devices A/S
Inventor: Kristian Larsen
IPC: A61L26/00 , B65D81/32 , A61K9/16 , B65B1/04 , A61K31/047 , A61K31/70 , A61K38/01 , A61L2/04 , A61L2/08 , A61L24/10 , A61L24/00 , A61L2/20 , A61L2/10 , A61L2/07
Abstract: The present invention relates to a dry composition, which upon addition of an aqueous medium forms a substantially homogenous paste suitable for use in haemostasis procedures. The paste forms spontaneously upon addition of the liquid, hence no mechanical mixing is required for said paste to form. The invention further relates to methods of preparing said dry composition, a paste made from said dry composition and use of said paste for medical and surgical purposes.
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公开(公告)号:US09265858B2
公开(公告)日:2016-02-23
申请号:US14516728
申请日:2014-10-17
Applicant: Ferrosan Medical Devices A/S
Inventor: Kristian Larsen
IPC: A61K38/48 , A61L24/10 , A61L24/00 , A61L2/04 , A61L2/08 , A61L2/10 , A61L2/20 , B65B1/04 , A61L2/07
CPC classification number: A61L26/0047 , A61K9/1658 , A61K31/047 , A61K31/70 , A61K38/014 , A61L2/04 , A61L2/07 , A61L2/081 , A61L2/082 , A61L2/087 , A61L2/10 , A61L2/202 , A61L2/204 , A61L2/206 , A61L2/208 , A61L24/0015 , A61L24/0036 , A61L24/104 , A61L26/00 , A61L26/0038 , A61L26/0066 , A61L2300/254 , A61L2300/418 , A61L2300/802 , A61L2400/04 , A61L2400/06 , B65B1/04 , B65D81/32
Abstract: Disclosed is a dry composition, which upon addition of an aqueous medium forms a substantially homogenous paste suitable for use in haemostasis procedures. The paste forms spontaneously upon addition of the liquid, hence no mechanical mixing is required for said paste to form. Further disclosed are methods of preparing said dry composition, a paste made from said dry composition and use of said paste for medical and surgical purposes.
Abstract translation: 公开了一种干组合物,其在添加水性介质时形成适用于止血程序的基本均匀的糊剂。 糊剂在加入液体后自发形成,因此不需要机械混合来形成所述糊料。 进一步公开的是制备所述干组合物的方法,由所述干组合物制成的糊剂和所述糊剂用于医疗和外科用途的方法。
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公开(公告)号:US20150045830A1
公开(公告)日:2015-02-12
申请号:US14383461
申请日:2013-03-05
Applicant: FERROSAN MEDICAL DEVICES A/S
Inventor: Mette Krog Jensen , Kristian Larsen
Abstract: The present invention relates to a container adapted to dispense its content under pressure. The container of the present invention consists of two separate compartments separated from one another by a slidable piston. The container of the present invention contains a haemostatic paste.
Abstract translation: 本发明涉及适于在压力下分配其内容物的容器。 本发明的容器由两个通过可滑动的活塞彼此分开的隔室组成。 本发明的容器含有止血膏。
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49.
公开(公告)号:US20140220130A1
公开(公告)日:2014-08-07
申请号:US14136578
申请日:2013-12-20
Applicant: Ferrosan Medical Devices A/S
Inventor: Kristian Larsen , Mads Sabra
CPC classification number: A61L24/0036 , A61L24/0015 , A61L24/102 , A61L24/104 , A61L26/0066 , A61L26/0085 , A61L2300/254 , A61L2300/418
Abstract: The present invention relates to a matrix material comprising a pharmaceutical composition such as a matrix material with a pharmaceutical composition printed on the surface. In one embodiment the pharmaceutical composition comprises thrombin. The invention further describes a method for making the matrix material with a pharmaceutical composition printed on the surface. In one specific embodiment the invention also relates to the use of said matrix material for promotion of hemostasis and/or wound healing. The invention also relates to a kit-of-parts comprising a matrix with a pharmaceutical composition and a container with a peelable lid.
Abstract translation: 本发明涉及一种基质材料,其包含药物组合物,例如具有印刷在表面上的药物组合物的基质材料。 在一个实施方案中,药物组合物包含凝血酶。 本发明进一步描述了制备具有印刷在表面上的药物组合物的基质材料的方法。 在一个具体实施方案中,本发明还涉及所述基质材料用于促进止血和/或伤口愈合的用途。 本发明还涉及包含具有药物组合物的基质和具有可剥离盖的容器的试剂盒。
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公开(公告)号:US20240315682A1
公开(公告)日:2024-09-26
申请号:US18259419
申请日:2022-01-14
Applicant: Ferrosan Medical Devices A/S
Inventor: Peter Lund Hammershøj , Henning Uzoma Igwebuike , Lisbeth Nøhr Demant , Christian Brüel , Mikael Engmark , Vikram Kjøller Bhatia , Lars Tamstrup Axelsson
CPC classification number: A61B17/00491 , A61B17/00234 , A61B34/30 , A61B2017/00115 , A61B2017/00398
Abstract: The present disclosure relates to a laparoscopic applicator for dispensing a substance, e.g. a substance comprising a haemostatic agent, at a selected site by means of a surgical robotic arm, the laparoscopic applicator comprising a delivery tube configured for holding the substance under a pressure; and an applicator tip connected to a distal end of the delivery tube, wherein the applicator tip is configured for being controllable operated by the robotic arm by being spatially manipulated by the robotic arm, and controllably releasing the substance from the delivery tube by the robotic arm.
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