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公开(公告)号：KR1020120132033A
公开(公告)日：2012-12-05
申请号：KR1020110050605
申请日：2011-05-27
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing non-ionic tea water derived from enzyme-inactivated raw tea leaves and a cosmetic product or pharmaceutical composition containing the same are provided to relieve inflammation and itching of a patient with atopic dermatitis and to prevent and treat atopic dermatitis. CONSTITUTION: A composition for preventing or treating atopic dermatitis contains 0.1-99 wt% of non-ionic tea water derived from enzyme-inactivated tea leaves as an active ingredient. The linalool concentration of the tea water is 5 ug or less. The tea water is prepared by inactivating tea leaf enzyme and juicing to prepare tea juice and removing ions from the tea juice. The tea juice is prepared by steaming, heating, or treating at high pressure.
Abstract translation: 目的：提供含有来源于酶灭活的生茶叶的非离子型茶水的组合物和含有该脱水茶叶的化妆品或药物组合物，以缓解具有特应性皮炎的患者的炎症和瘙痒，并预防和治疗特应性皮炎。 构成：用于预防或治疗特应性皮炎的组合物含有0.1-99重量％的来源于酶灭活的茶叶作为活性成分的非离子型茶水。 茶水的芳樟醇浓度为5ug以下。 茶水通过灭活茶叶酶和榨汁来制备茶汁并从茶汁中除去离子。 茶汁通过蒸汽，加热或高压处理来制备。
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公开(公告)号：KR1020110045662A
公开(公告)日：2011-05-04
申请号：KR1020090102325
申请日：2009-10-27
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition containing green tea polysaccharide and Tricholoma matsutake extract for antiaging is provided to promote aging due to UV ray and environmental pollution. CONSTITUTION: A cosmetic composition contains 0.01-20.0 weight% of green tea polysaccharide and Tricholoma matsutake extract in a mixture ratio of 1.0:10.0-10.0:1.0 as an active ingredient. The green tea polysaccharide is prepared by extracting green tea leaves at 80-90°C, concentrating, filtering to remove impurities, adding ethanol by dropwise, and performing hot wind drying.
Abstract translation: 目的：提供一种含有绿茶多糖和抗秋水仙碱提取物的化妆品组合物，以促进由于紫外线和环境污染引起的老化。 构成：作为活性成分，化妆品组合物含有0.01-20.0重量％的绿茶多糖和茯苓提取物，混合比为1.0:10.0-10.0:1.0。 绿茶多糖通过在80-90℃下提取绿茶叶来制备，浓缩，过滤除去杂质，滴加乙醇，进行热风干燥。
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43.发明授权ＣＰＴ-１ 유전자의 발현을 특이적으로 전사 단계에서조절하는 화학물질의 스크리닝 방법 및 그 방법으로검색된 제니스테인을 유효 성분으로 포함하는 ＣＰＴ-１발현 촉진제 有权用于表达CPT-1基因的控制剂的筛选方法，以及通过该方法筛选的包含染料木素的CPT-1表达增强子
公开(公告)号：KR100994632B1
公开(公告)日：2010-11-15
申请号：KR1020030095226
申请日：2003-12-23
Applicant: (주)아모레퍼시픽
IPC: C12N15/85
Abstract: 본 발명은, CPT-1 프로모터와 루시퍼라제를 포함하는 재조합 플라스미드; 상기 플라스미드로 형질전환된 Huh7 세포주 (수탁번호: KCLRF-BP-00090); 상기 세포를 이용하는 것을 특징으로 하는, CPT-1 유전자의 발현을 특이적으로 전사 단계에서 조절하는 화학물질의 스크리닝 방법에 관한 것이며,
또한 본 발명은, 상기의 스크리닝 방법으로 검색된 제니스테인을 유효 성분으로 포함하는 CPT-1 발현 촉진제; 그리고 상기의 스크리닝 방법으로 검색된 제니스테인을 유효 성분으로 포함하는 지방산의 베타 산화 촉진제에 관한 것이다.
제니스테인, CPT-1 유전자, 지방산의 베타 산화촉진제.-
公开(公告)号：KR1020090128677A
公开(公告)日：2009-12-16
申请号：KR1020080054540
申请日：2008-06-11
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K2800/80 , A61Q19/08
Abstract: PURPOSE: A cosmetic composition containing Cornus officinalis extract for antiaging is provided to suppress the collagenase expression and procollagen synthesis promotion. CONSTITUTION: A cosmetic composition for antiaging contains Cornus officinalis extract as an active ingredient. A method for processing Cornus officinalis: a process of boiling, roasting, steaming Cornus officinalis; and a step of extracting Cornus officinalis using water or organic solvent. The organic solvent is ethanol, methanol, butanol, ether, ethylacetate, chloroform or mixture solvent.
Abstract translation: 目的：提供含有枸杞提取物用于抗衰老的化妆品组合物，以抑制胶原酶表达和前胶原合成促进。 构成：抗衰老的化妆品组合物含有枸杞提取物作为活性成分。 一种加工枸杞的方法：一种沸腾，焙烧，蒸a的方法。 并使用水或有机溶剂提取枸杞子的步骤。 有机溶剂为乙醇，甲醇，丁醇，乙醚，乙酸乙酯，氯仿或混合溶剂。
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45.发明授权Ｒｈｏ ＧＤＩ-α를 포함하는 멜라닌 생성 조절용 조성물및 Ｒｈｏ ＧＤＩ-α를 이용하여 멜라닌 생성 조절제를스크리닝하는 방법 失效用于控制含有Rho GDI-的黑素生成的组合物，以及使用Rho GDI-α筛选黑素生成调节剂的方法
公开(公告)号：KR100912355B1
公开(公告)日：2009-08-14
申请号：KR1020070121200
申请日：2007-11-27
Applicant: (주)아모레퍼시픽
Abstract: Rho GDI-α 단백질 또는 그 단백질을 코딩하는 유전자를 이용하여 멜라닌 생성을 억제하는 조성물과 Rho GDI-α 단백질을 이용하여 멜라닌 생성을 억제하는 물질을 스크리닝하는 방법이 개시된다. 또한, Rho GDI-α의 발현을 저해하는 siRNA 유전자를 이용하여 멜라닌 생성을 촉진하는 조성물과 siRNA 유전자를 이용하여 멜라닌 생성을 촉진하는 물질을 스크리닝하는 방법이 개시된다. 본 발명을 이용하면 멜라닌 생성을 효과적으로 촉진 또는 억제할 수 있으며 멜라닌 생성을 촉진 또는 억제하는 물질을 효과적으로 스크리닝할 수 있다.
Rho GDI-α, MITF, 타이로시나제, 멜라닌 생성 촉진, 멜라닌 생성 억제, 멜라닌-
Patent Agency Ranking
公开(公告)号：KR100774437B1
公开(公告)日：2007-11-08
申请号：KR1020060113662
申请日：2006-11-17
Applicant: (주)아모레퍼시픽
IPC: A61K31/343 , A61K8/49 , A61Q19/02
CPC classification number: A61K8/4973 , A61K31/343 , A61Q19/02
Abstract: A skin external composition for skin-whitening containing manassantin B is provided to inhibit mobility of melanin by inhibiting binding of melanophilin as a carrier of melanosome in a melanocyte with myosin 5a, thereby forming melanosome aggregation and whitening the skin. A skin external composition for skin-whitening contains 0.001-10% of manassantin B which is extracted from Saururus chinensis Baill by extracting Saururus chinensis Baill with water or organic solvent selected from ethanol, methanol, butanol, ether, ethylacetate, chloroform and methylene chloride, filtering the extract, concentrating the filtered solution under reduced pressure, extracting the concentrate with methylene chloride and concentrating the extract under reduced pressure, and is formulated as solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation or spray.
Abstract translation: 提供含有马桑丁汀B的皮肤外用组合物，用于通过抑制作为黑素细胞的黑素体的载体的黑色素细胞与肌球蛋白5a的结合来抑制黑色素的迁移，从而形成黑素体聚集并使皮肤变白。 用于皮肤美白的皮肤外用组合物含有0.001-10％的苦参碱B，其通过用水或选自乙醇，甲醇，丁醇，乙醚，乙酸乙酯，氯仿和二氯甲烷的有机溶剂萃取中华白菜， 过滤浓缩滤液，减压浓缩萃取液，减压浓缩，配制成溶液，悬浮液，乳液，糊剂，凝胶，乳液，乳液，粉末，皂，表面活性剂， 含有清洁，油，粉底，乳液粉底，蜡基或喷雾剂。
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公开(公告)号：KR101817242B1
公开(公告)日：2018-01-10
申请号：KR1020110128446
申请日：2011-12-02
Applicant: (주)아모레퍼시픽
IPC: A61K36/234 , A61P17/00 , A61K8/97 , A61Q19/00
Abstract: 본발명은갯방풍() 추출물을함유하는피부외용제조성물에관한것으로서, 보다상세하게는갯방풍추출물을함유함으로써피부노화방지효과를제공할수 있는조성물에관한것이다.
Abstract translation: 本发明涉及一种含有一个防风康吉（）提取物，组合物，可以更具体地，涉及由含有所述提取物康格防风提供抗老化效果的皮肤外用组合物。
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