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公开(公告)号：KR1020120095049A
公开(公告)日：2012-08-28
申请号：KR1020110014441
申请日：2011-02-18
Applicant: (주)아모레퍼시픽
CPC classification number: A61Q19/02 , A61K8/97 , A61K2800/5922 , A61Q19/00
Abstract: PURPOSE: A cosmetic composition for skin whitening is provided to sooth melanocyte and to seclude stimulation caused by inflammation, UV and melasma blood vessels. CONSTITUTION: A cosmetic composition for skin whitening includes Magnolia Obovata Bark Extract, Citrus Unshiu Peel Extract, Wild Soybean Extract, Ginko Biloba Leaf Extract or Honeysuckle Flower Extract as an active ingredient. 0.01-10 weight% of the Magnolia Obovata Bark Extract, Citrus Unshiu Peel Extract, Wild Soybean Extract, Ginko Biloba Leaf Extract or Honeysuckle Flower Extract is contained for the total weight. The composition additionally contains one or more from glucoside, glycyrrhiza extract, arbutin, ascorbic acid or kojic acid. The composition fundamentally secludes the production of melanin inside the skin or composition easily eliminates the melanin inside the skin. The composition improves chromatosis and skin tone down phenomenon. The composition reduces amount of the skin keratinocytes.
Abstract translation: 目的：提供用于皮肤美白的化妆品组合物，用于消除黑素细胞，并分泌由炎症，紫外线和黑斑病血管引起的刺激。 构成：用于皮肤美白的化妆品组合物包括玉兰木皮提取物，柑橘果皮提取物，野生大豆提取物，银杏叶提取物或金银花提取物作为活性成分。 总重量含有0.01-10重量％的木兰花果皮提取物，柑橘类未提取物，野生大豆提取物，银杏叶提取物或金银花提取物。 该组合物另外含有一种或多种来自葡萄糖苷，甘草提取物，熊果苷，抗坏血酸或曲酸。 该组合物从根本上隐藏在皮肤或组合物内的黑色素的产生容易消除皮肤内的黑色素。 该组合物可改善色素沉着和皮肤色调现象。 组合物减少皮肤角质形成细胞的量。
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42.发明公开Ｋｌｏｔｈｏ 유전자를 포함하는 피부 활성물질 탐색용 키트 및 이를 이용하여 피부 활성물질을 탐색하는 방법 审中-实审包含KLOTHO基因的皮肤活性成分的检测工具和使用其检测皮肤活性成分的方法
公开(公告)号：KR1020120049126A
公开(公告)日：2012-05-16
申请号：KR1020110107409
申请日：2011-10-20
Applicant: (주)아모레퍼시픽
CPC classification number: G01N33/5044 , C12Q1/6876 , C12Q1/6883 , C12Q2600/148 , C12Q2600/158 , G01N33/5023 , G01N33/6881 , G01N33/5302
Abstract: PURPOSE: A kit for detecting a skin active material and a detection method using the same are provided to quickly and simply screen antioxidative, whitening and moisturizing materials. CONSTITUTION: A kit for detecting a skin active material contains Klotho protein gene, primer for amplifying the gene of sequence numbers 1 and 2, a probe of sequence number 3, and a material which enhances Klotho protein expression level in skin cells. The skin active material is a material for moisturizing, anti-aging, or whitening. The skin cells are human keratinocytes, fibroblast, or melanocytes.
Abstract translation: 目的：提供用于检测皮肤活性物质的试剂盒和使用其的检测方法，以快速且简单地筛选抗氧化，美白和保湿材料。 构成：用于检测皮肤活性物质的试剂盒含有Klotho蛋白质基因，用于扩增序列号1和2的基因的引物，序列号3的探针和增强皮肤细胞中Klotho蛋白表达水平的材料。 皮肤活性物质是保湿，抗衰老或美白的材料。 皮肤细胞是人角质形成细胞，成纤维细胞或黑素细胞。
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公开(公告)号：KR1020100106754A
公开(公告)日：2010-10-04
申请号：KR1020090024900
申请日：2009-03-24
Applicant: (주)아모레퍼시픽
IPC: A61K8/97 , A61Q19/02 , A61K36/185 , A61P17/00
Abstract: PURPOSE: A composition containing Homalium longifolium extract for skin whitening is provided to suppress c-kit protein activation and signal transduction in melanocytes. CONSTITUTION: A composition for skin whitening contains 0.0001-10 weight% of Homalium longifolium extract as an active ingredient. The Homalium longifolium extracts suppresses c-kit activation. The Homalium longifolium extract controls melanocyte function by suppressing signal transduction in melanocytes. The composition for skin whitening is used in the form of emulsion, cream, essence, pack, gel, powder, makeup base, foundation, lotion, ointment, body lotion, body cream, body oil, shampoo, rinse, soap, and hair dye.
Abstract translation: 目的：提供一种含有长白containing提取物用于皮肤美白的组合物，以抑制黑素细胞中的c-kit蛋白激活和信号转导。 构成：用于皮肤美白的组合物含有0.0001-10重量％的枸杞提取物作为活性成分。 枸杞提取物抑制c-kit活化。 Homalium longifolium提取物通过抑制黑素细胞中的信号转导来控制黑素细胞功能。 用于皮肤美白的组合物以乳液，乳膏，精华，包装，凝胶，粉末，化妆底，基础，洗剂，软膏，身体乳液，身体霜，身体油，洗发剂，漂洗剂，肥皂和染发剂的形式使用 。
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44.发明公开Ｒｈｏ ＧＤＩ-α를 포함하는 멜라닌 생성 조절용 조성물및 Ｒｈｏ ＧＤＩ-α를 이용하여 멜라닌 생성 조절제를스크리닝하는 방법 失效用于控制含有RHO GDI-α的成血作用的组合物，以及使用RHO GDI-α筛选造血调节剂的方法;
公开(公告)号：KR1020090054505A
公开(公告)日：2009-06-01
申请号：KR1020070121200
申请日：2007-11-27
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/64 , A61Q19/02 , G01N33/5008 , G01N2500/04
Abstract: A composition for regulating melanogenesis, which contains RhoGDI-alpha is provided to efficiently promote or inhibit melanogenesis using siRNA gene which suppresses RhoGDI-alpha expression. A composition for regulating melanogenesis comprises a RhoGDI-alpha protein or gene coding the same or a complementary gene of RhoGDI-alpha gene. The composition for regulating melanogenesis inhibits the expressions of MITF and tyrosinase. The composition for regulating melanogenesis promotes the expression of MITF and tyrosinase. A screening method of the composition for regulating melanogenesis includes confirmation of regulation of RhoGDI-alpha expression, activation or function.
Abstract translation: 提供了含有RhoGDI-α的用于调节黑素生成的组合物，用于抑制RhoGDI-α表达的siRNA基因有效促进或抑制黑素生成。 用于调节黑素生成的组合物包含编码RhoGDI-α基因相同或互补基因的RhoGDI-α蛋白或基因。 用于调节黑素生成的组合物抑制MITF和酪氨酸酶的表达。 用于调节黑素生成的组合物促进MITF和酪氨酸酶的表达。 用于调节黑素生成的组合物的筛选方法包括确认RhoGDI-α表达的调节，活化或功能。
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Patent Agency Ranking
公开(公告)号：KR1020170061308A
公开(公告)日：2017-06-05
申请号：KR1020150166152
申请日：2015-11-26
Applicant: (주)아모레퍼시픽
Abstract: 본명세서에는헤어세정용조성물이개시된다. 상기조성물은알킬글루코시드를포함하는비이온계면활성제및 알킬기를포함하는양이온치환셀룰로오즈를포함한다. 본명세서에개시된기술은비이온계면활성제세정시스템에서기포력및 컨디셔닝이향상된저자극헤어세정용조성물을제공하는효과가있다.
Abstract translation: 本文公开了用于头发清洁的组合物。 该组合物包含含有烷基葡糖苷和含有烷基的阳离子取代纤维素的非离子表面活性剂。 在此描述的技术高恩妃离子表面活性剂的清洁系统是有效的，以提供改进的低变应原性洗发发泡能力和调理组合物。
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公开(公告)号：KR101739330B1
公开(公告)日：2017-05-24
申请号：KR1020100107001
申请日：2010-10-29
Applicant: (주)아모레퍼시픽
CPC classification number: C12Q1/025 , C12N5/0698 , G01N33/5044
Abstract: 본발명은실제진피와유사한구조를가지는진피모사체를제작하여진피모사체의변형정도차이를 3차원으로시각화하여나타냄으로써피부탄력증진효능을평가하는방법에관한것이다.
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公开(公告)号：KR1020170007518A
公开(公告)日：2017-01-18
申请号：KR1020170005274
申请日：2017-01-12
Applicant: (주)아모레퍼시픽
IPC: A61K31/352 , A61K8/49 , A61Q19/08
Abstract: 본발명은아멘토플라본을유효성분으로함유하는자외선에의한세포손상방지용또는노화억제용조성물을제공한다. 본발명의조성물은자외선에의해변형된라민 A 단백질발현을조절하거나, 인산화된 H2AX 단백질발현을조절하고, 세포핵막손상을방지하여, 피부세포의손상을방지하는효과가있다. 그래서, 화장료조성물이나약학조성물로활용이가능하다.
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公开(公告)号：KR101481167B1
公开(公告)日：2015-01-14
申请号：KR1020080059873
申请日：2008-06-24
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 피부세포의 증식을 촉진하는 방법 및 이카리시드 II(Icariside II)를 유효 성분으로 함유하는 피부 재생 촉진용 조성물을 개시한다.
본 발명에 따른 피부세포의 증식을 촉진하는 방법 및 조성물은 표피의 재생에 관여하는 피부 표피 기저층의 전이-증폭 세포의 증식을 촉진할 수 있는 바, 이를 통해 피부의 재생을 촉진할 수 있다.
전이-증폭 세포, 피부 재생-
公开(公告)号：KR1020140064272A
公开(公告)日：2014-05-28
申请号：KR1020120131433
申请日：2012-11-20
Applicant: (주)아모레퍼시픽
CPC classification number: G01N33/5308 , C12Q1/6851 , G01N33/15 , G01N33/5008
Abstract: The present invention relates to a method for screening effective substances related to skin-whitening, and more specifically, to a method which checks reduction of PGE_2 (prostaglandin E_2) generation related to melanin production and movement through measurement of a TRPM8 gene expression amount and screens substances effective to skin-whitening using the same.
Abstract translation: 本发明涉及一种筛选与皮肤美白相关的有效物质的方法，更具体地说，涉及通过测定TRPM8基因表达量和筛选来检查与黑色素产生和运动相关的PGE_2（前列腺素E_2）生成减少的方法 使用该物质对皮肤美白有效的物质。
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