Abstract:
A skin external composition is provided to increase production of tropoelastin in the skin, and productions of collagen and fibrilin in the dermis layer, so that the composition is useful for skin wrinkle improvement, skin elasticity enhancement, and skin moisturizing increase. The skin external composition for improving skin wrinkle, enhancing skin elasticity and increasing skin moisturizing comprises a mixture containing palmitoylpentapeptide, soybean embryo isoflavone aglycon, extract of Medicago sativa and extract of Iris florenti, wherein the palmitoylpentapeptide is prepared by binding a palmitoyl group to 5 amino acid chain molecule(Lys-Thr-Thr-Lys-Ser) corresponding with the protein base of collagen; the soybean embryo isoflavone aglycon is selected from genistin, daidzin, glycitin, genistein, daidzein and glycitein; and the amounts of palmitoylpentapeptide, soybean embryo isoflavone aglycon, extract of Medicago sativa and extract of Iris florenti are 0.001-20 wt.%, 0.001-20 wt.%, 0.001-20 wt.% and 0.001-20 wt.%, respectively.
Abstract:
본 발명은 2-(3,4-다이플루오로페닐)-3-프로필-2-사이클로펜텐-1-온 옥심 또는 허용가능한 그의 염을 유효성분으로 함유하는 피부노화 및 주름 방지용 화장료 조성물에 관한 것으로, 본 발명의 화장료 조성물은 피부내 염증을 억제하는 2-(3,4-다이플루오로페닐)-3-프로필-2-사이클로펜텐-1-온 옥심을 유효성분으로 함유하여 피부노화 및 주름 방지에 효과적으로 사용될 수 있다.
Abstract:
본발명은진세노사이드 Rg1을유효성분으로함유하고, 상기진세노사이드 Rg1은서리아신을억제하는것을특징으로하는피부외용제조성물에관한것이다. 본발명에따른피부외용제조성물은피부질환예방및 경감용또는피부보습용으로사용될수 있다. 이때, 상기피부질환은아토피또는건선을포함한다. 본발명의피부외용제조성물은서리아신이유발하는피부각질세포형성의이상현상을저지할수 있으며, 이에따라피부질환을예방또는경감할수 있고, 피부수분함유량을향상시킬수 있다.
Abstract:
The present invention relates to a composition containing deep ocean water for skin moisturizing and, more specifically, to a composition containing deep ocean water for skin moisturizing which comprises manganese, calcium, and potassium in a content ratio (w/v) of 2-4: 0.5-1.5: 0.5-1.5.
Abstract:
본발명은α-케토글루타레이트(α-ketoglutarate)를함유하는주름개선용화장료조성물에관한것으로, 보다상세하게는α-케토글루타레이트가콜라겐의주요구성아미노산인프롤린의공급에관여하는프롤리다아제활성을증가시킴으로써콜라겐생성을촉진시키는주름개선용화장료조성물에관한것이다. 또한, 본발명에의한화장료조성물은상기α-케토글루타레이트와함께α-리포익산(α-lipoic acid)을유효성분으로더 함유할수 있으며, 상기α-리포익산은프롤릴-4-수산화효소발현을증가시켜생성된프로콜라겐이올바른삼중나선(triple helix)을형성시키는역할을한다. 즉, 본발명에의한화장료조성물은프롤리다아제활성을증가시키는α-케토글루타레이트와함께α-리포익산을함유함으로써콜라겐생합성을촉진시킨다.
Abstract:
PURPOSE: A kit for detecting a skin active material and a detection method using the same are provided to quickly and simply screen antioxidative, whitening and moisturizing materials. CONSTITUTION: A kit for detecting a skin active material contains Klotho protein gene, primer for amplifying the gene of sequence numbers 1 and 2, a probe of sequence number 3, and a material which enhances Klotho protein expression level in skin cells. The skin active material is a material for moisturizing, anti-aging, or whitening. The skin cells are human keratinocytes, fibroblast, or melanocytes.