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公开(公告)号：KR101823343B1
公开(公告)日：2018-01-31
申请号：KR1020150156097
申请日：2015-11-06
Applicant: 대한민국(농촌진흥청장)
IPC: C07J9/00 , C07J17/00 , C07J75/00 , A61K31/575 , A61K31/56 , A61K31/4188
Abstract: 본발명은 20(S)-프로토파낙사트리올또는이의염을유효성분으로포함하는테모졸로마이드의항암활성증진용조성물, 이를포함하는기능성식품및 테모졸로마이드와 20(S)-프로토파낙사트리올또는이의염을유효성분으로포함하는암을치료하기위한약학적조성물에관한것으로, 보다구체적으로테모졸로마이드(temozolomide, TMZ)를 20(S)-프로토파낙사트리올또는이의염과병용처리시 발생하는상승적인항암효과(synergistic anti-cancer effect)를이용하여암을효과적으로치료할수 있는, 20(S)-프로토파낙사트리올또는이의염을유효성분으로포함하는테모졸로마이드의항암활성증진용조성물, 이를포함하는기능성식품및 테모졸로마이드와 20(S)-프로토파낙사트리올또는이의염을유효성분으로포함하는암을치료하기위한약학적조성물에관한것이다.
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公开(公告)号：KR1020170054157A
公开(公告)日：2017-05-17
申请号：KR1020150156934
申请日：2015-11-09
Applicant: 대한민국(농촌진흥청장)
IPC: A23L1/30 , A61K36/258
Abstract: 인삼추출물을유효성분으로포함하는인지기능개선용조성물에관한것으로, 보다자세하게는인삼의알코올추출물과추출후 남은인삼여과물의물 추출물을혼합한혼합물을유효성분으로포함하는인지기능개선용조성물, 건강기능식품, 약학적조성물, 식품첨가물및 이의제조방법에관한것이다. 본발명의인삼추출물은인지기능에장애를가진환자들의학습능력또는기억력등 전체적인지기능을개선시키는효과가있다.
Abstract translation: 本发明涉及人参提取物的组合物用于改善认知功能，包括作为活性成分的，并且更特别的人参乙醇提取物和水的混合物中提取的剩余人参滤液组合物后，混合提取物，以改善其包含作为活性成分的认知功能，健康 功能性食品，药物组合物，食品添加剂及其制造方法。 改善整体支持功能，如本发明的人参提取物的效果是学习患者认知障碍容量或存储器。
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公开(公告)号：KR1020170049362A
公开(公告)日：2017-05-10
申请号：KR1020160071009
申请日：2016-06-08
Applicant: 대한민국(농촌진흥청장) , (주) 와이디생명과학
IPC: A61K36/481 , A61K36/30 , A23L1/30
CPC classification number: A61K36/481 , A23L33/105 , A23V2002/00 , A23V2200/30 , A61K36/30 , A61K2300/00
Abstract: 본발명은황기추출물및 지치추출물을유효성분으로포함하는관절염예방또는치료용약학적조성물에관한것으로서, 보다상세하게는연골기질물질분해효소(matrix metalloprotease; MMP)-1, MMP-3, MMP-13의활성을저해하고염증으로인한통증을억제하여관절염예방또는치료활성을갖는황기추출물및 지치추출물을유효성분으로포함하는관절염예방또는치료용약학적조성물, 관절염예방또는개선용건강기능식품, 염증성통증완화또는억제용조성물및 염증성통증완화또는개선용건강기능식품에관한것이다.
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公开(公告)号：KR101522584B1
公开(公告)日：2015-05-27
申请号：KR1020130109830
申请日：2013-09-12
Applicant: 대한민국(농촌진흥청장)
IPC: A61K31/704 , A61K31/70 , A61P29/00
Abstract: 본발명은진세노사이드 Rh6를포함하는피부외용제에관한것으로서, 보다상세하게는세포독성이없어인체에무해하며부작용이거의없어장기간사용하는데무리가없고, 생성된일산화질소를억제하여항염증효능에탁월한염증성질환의예방또는치료용피부외용제에관한것이다.
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公开(公告)号：KR1020140111186A
公开(公告)日：2014-09-18
申请号：KR1020130025147
申请日：2013-03-08
Applicant: 대한민국(농촌진흥청장)
Abstract: The present invention relates to a composition comprising a Physalis angulata extract for inhibiting cell aging. The composition, comprising the Physalis angulata extract having an excellent effect of inhibiting cell aging as an active ingredient, can be used for preventing age-related diseases, such as skin aging, rheumatoid arthritis, osteoarthritis, hepatitis, chronic damage to skin tissues, arteriosclerosis, prostatic hyperplasia, or liver cancer.
Abstract translation: 本发明涉及包含抑制细胞衰老的苦参提取物的组合物。 包含抑制细胞衰老作为活性成分的极好效果的ang ata提取物的组合物可以用于防止与老年有关的疾病，例如皮肤老化，类风湿性关节炎，骨关节炎，肝炎，对皮肤组织的慢性损伤，动脉硬化 ，前列腺增生或肝癌。
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Patent Agency Ranking
公开(公告)号：KR1020140082052A
公开(公告)日：2014-07-02
申请号：KR1020120151215
申请日：2012-12-21
Applicant: 대한민국(농촌진흥청장)
IPC: A61K31/343 , A61K31/34 , A61K36/07 , A61P25/28
CPC classification number: A61K31/407 , A61K31/365 , A61K36/07
Abstract: The present invention relates to an achetylcholinesterase activity inhibitor, a pharmaceutical composition for preventing or treating dementia, a cerebral nerve protecting agent, and a method for producing the same, wherein the achetylcholinesterase activity inhibitor includes one or more compounds selected from the group consisting of Chemical Formula 1 to 4 or pharmaceutically acceptable salts of the same as active ingredients. [Chemical Formula 1][Chemical Formula 2][Chemical Formula 3][Chemical Formula 4].
Abstract translation: 本发明涉及一种乙酰胆碱酯酶活性抑制剂，一种预防或治疗痴呆的药物组合物，一种脑神经保护剂及其制备方法，其中所述的Achet胆碱酯酶活性抑制剂包括一种或多种选自化学 式1至4或与活性成分相同的药学上可接受的盐。 [化学式1] [化学式2] [化学式3] [化学式4]。
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公开(公告)号：KR1020140052453A
公开(公告)日：2014-05-07
申请号：KR1020120118556
申请日：2012-10-24
Applicant: 대한민국(농촌진흥청장)
IPC: A61K36/185 , A61K36/18 , A61P29/00 , A61P17/00
Abstract: The present invention relates to a pharmaceutical composition and health functional food comprising an Abutilon theophrasti medicus leaf extract as an effective component, and specifically, to a pharmaceutical composition and health functional food having anti-inflammation, anti-oxidative, and anti-arteriosclerotic activities. The Abutilon theophrasti medicus leaf extract is an extract of C1-C4 alcohol.
Abstract translation: 本发明涉及一种药物组合物和保健功能食品，其包含作为有效成分的芸香属植物提取物，具体涉及具有抗炎，抗氧化，抗动脉硬化活性的药物组合物和保健功能食品。 Abutilon theophrasti药用叶提取物是C1-C4醇的提取物。
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48.发明授权
公开(公告)号：KR101388597B1
公开(公告)日：2014-04-24
申请号：KR1020120005085
申请日：2012-01-17
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 골관절염 예방 및 치료를 위해, 지치 뿌리의 천연 색소를 함유하는 조성물 및 이의 제조 방법에 관한 것이다.
본 발명의 지치 뿌리 추출물을 함유하는 조성물은 단독으로 사용되더라도 골관절염에 유의한 작용효과를 보여주어, 골관절염 예방제 및 치료제 또는 골관절염 건강 기능식품으로도 널리 활용될 수 있다.-
49.发明公开노루궁뎅이 버섯에서 추출된 특정물질을 유효성분으로 포함하는 치매 예방 또는 치료용 약제학적 조성물 및 그 제조방법 有权用于治疗由埃塞克斯提取的特异性物质进行灭绝或治疗的药物组合物及其制备方法
公开(公告)号：KR1020130118131A
公开(公告)日：2013-10-29
申请号：KR1020120041087
申请日：2012-04-19
Applicant: 대한민국(농촌진흥청장)
IPC: A61K31/4045 , A61K31/404 , A61K31/4035 , A61K36/07
CPC classification number: A61K31/4035 , A61K36/07
Abstract: PURPOSE: A pharmaceutical composition for preventing or treating dementia is provided to suppress the activity of acetylcholine esterase, to effectively prevent and treat dementia, and to produce a pharmaceutical composition and a health food. CONSTITUTION: An inhibitor of acetylcholine esterase activation contains a compound of chemical formula 1 or a pharmaceutically acceptable salt thereof as an active ingredient. The compounds are derived from Hericium erinacium. A method for manufacturing the inhibitor comprises the steps of: pulverizing Hericium erinacium; adding alcohols to the pulverized Hericium erinacium and concentrating the extract by reduced pressure; preparing a primary fraction from the concentrated extract using an organic solvent; preparing a secondary fraction from the primary fraction through chromatography; and isolating and purifying the compound of chemical formula 1.
Abstract translation: 目的：提供用于预防或治疗痴呆的药物组合物，以抑制乙酰胆碱酯酶的活性，有效预防和治疗痴呆，以及制备药物组合物和保健食品。 构成：乙酰胆碱酯酶活化抑制剂含有化学式1的化合物或其药学上可接受的盐作为活性成分。 该化合物衍生自赫氏酵母（Hericium erinacium）。 制备抑制剂的方法包括以下步骤：粉碎赫氏酵母; 向粉碎的Hericium erinacium中加入醇，并通过减压浓缩提取物; 使用有机溶剂从浓缩提取物中制备一级馏分; 通过色谱从一级馏分制备二级馏分; 并分离和纯化化学式1的化合物。
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公开(公告)号：KR1020120087605A
公开(公告)日：2012-08-07
申请号：KR1020110008900
申请日：2011-01-28
Applicant: 대한민국(농촌진흥청장) , 경희대학교 산학협력단
IPC: A61K36/258 , A61P25/28 , A61P25/00
CPC classification number: A61K36/258 , A23V2200/322
Abstract: PURPOSE: A composition containing ginseng for improving a cognitive function is provided to improve visual linguistics learning and visual memory recalling abilities. CONSTITUTION: A composition for improving a cognitive function contains ginseng as an active ingredient. The ginseng is white and red ginseng. The white ginseng is prepared removing peel of 4-year old raw ginsengs and drying. The red ginseng is prepared by steaming the raw ginseng. The cognitive function is a visual cognitive function.
Abstract translation: 目的：提供含有提高认知功能的人参的组合物，以改善视觉语言学习和视觉记忆能力。 构成：用于改善认知功能的组合物含有人参作为活性成分。 人参是白参和红参。 白参，准备去除4年生人参脱皮干燥。 红参是通过蒸制生的人参制成的。 认知功能是视觉认知功能。
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