Abstract:
c-Met 및 EGFR 이중저해제및 IGF-1R 저해제를유효성분으로포함하는암의예방및/또는치료를위한병용투여용약학조성물, IGF-1R 저해제의항 c-Met 및 EGFR 이중저해제효능증진(저항성극복) 용도, 및 c-Met 및 EGFR 이중저해제에대한저항성마커로서의 IGF-1R의용도가제공된다.
Abstract:
Provided are a pharmaceutical composition comprising an EGFR antagonist and an anti-c-Met antibody as active ingredients for a combination therapy for preventing and/or treating diseases caused by c-Met or EGFR. The pharmaceutical composition for a combination therapy has an excellent synergistic effect and can exhibit the effect even when having a resistance to EGFR antagonist, thereby can more effectively perform the treatment.
Abstract:
The present invention relates to: a biomarker for identifying a subject for the application of anti c-Met antibodies; a method of identifying the subject for the application of the anti c-Met antibodies including a step of measuring the Cbl concentration, the Cbl mutation, and/or the mutation of a Cbl combining domain of c-Met of tumour cells of the subject; and a preventing and/or treating method of c-Met related diseases including a step of injecting an effective dose of the anti c-Met antibodies to the subject.
Abstract:
PURPOSE: An anti-c-Met antibody and a pharmaceutical composition containing the same are provided to effectively prevent or treat cancer. CONSTITUTION: An anti-c-Met antibody comprises the followings: a heavy chain variable region containing one or more heavy chain complementarily determining regions selected from CDR-H1 with an amino acid sequence of sequence number 4, CDR-H2 with an amino acid sequence of sequence number 5, and CDR-H3 with an amino acid sequence of sequence number 6; and a heavy chain variable region containing one or more heavy chain complementarily determining regions selected from the group consisting of CDR-L1 with an amino acid sequence of sequence number 7, CDR-L2 with an amino acid sequence of sequence number 8, and CDR-L3 with an amino acid sequence of sequence number 9.
Abstract:
An ink composition comprising dipropylene glycol monomethyl ether acetate (DPMA). For example, an ink composition for a color filter includes a binder material, a monomer material, a polymerization initiator, a pigment dispersion, and a solvent including dipropylene glycol monomethyl ether acetate (DPMA).
Abstract:
An electronic programme guide detects internet distributed guide information (502) on current broadcasts and displays it (507) in part or all (510) of a display zone using a graphic processor allowing selection from a list (502) of detailed information for a programme (513) or channel (509) selected.
Abstract:
PURPOSE: A system and a method for retrieving broadcasting program information are provided to quickly and easily retrieve information about a broadcasting program for which a televiewer wishes by providing a keyword with a high retrieval frequency number to the televiewer. CONSTITUTION: At least one digital receiving device(200) detects a broadcasting signal or broadcasting detailed information about at least one keyword from a digital signal transmitted from a transmitter(100). A server(300) has the first DB(310). The first DB(310) stores a keyword inputted from an external device by ranking according to a retrieval frequency number. The server(300) extracts at least one keyword located within certain ranking from the first DB(310), and transmits the extracted keyword to the transmitter(100). The digital receiving device(200) displays at least one keyword transmitted from the transmitter(100) according to a set arrangement pattern.
Abstract:
PURPOSE: A method and system for providing electric program guide information are provided to offer guide information about a broadcasting program to viewers while minimizing a portion of a screen, which is covered by the guide information. CONSTITUTION: A guide information detector(407) detects guide information included in a received broadcasting signal. A storage unit(408) stores the detected guide information. A system controller(409) outputs guide information of a program currently being broadcasted through each channel among the guide information stored in the storage unit from the storage unit when a user requests the guide information. A display(406) displays the guide information output from the storage unit on a part of a display area. A graphic engine(411) forms a display form of the guide information output from the storage unit to provide the guide information to the display so that the display displays the guide information.