公开(公告)号：KR100492270B1

公开(公告)日：2005-05-30

申请号：KR1020020036481

申请日：2002-06-27

Applicant: 재단법인서울대학교산학협력재단

Inventor： 김현이 ,  김해원

IPC: A61L27/10

Abstract: 본 발명은 생체 이식용 세라믹 복합체 및 그 제조 방법에 관한 것으로, 복합체는 수산화아파타이트(hydroxyapatite)의 수산화이온(OH-)을 불소이온(F-)으로 치환(substitution)시킨 불-수산화아파타이트(fluor-hydroxyapatite) 기지상 (matrix)과 상기 기지상 내에 위치하는 세라믹 재료로 이루어진 2차상(second phase)으로 이루어진다. 불소이온의 치환은 수산화아파타이트와 2차상간의 반응을 억제시켜 주며, 2차상은 불-수산화아파타이트 기지상의 기계적 물성(mechanical properties)을 향상시키는 역할을 한다.

公开(公告)号：KR100465584B1

公开(公告)日：2005-01-13

申请号：KR1020020027453

申请日：2002-05-17

Applicant: 재단법인서울대학교산학협력재단

Inventor： 김현이 ,  박근태

IPC: H01L41/22 ,  G01L9/08

Abstract: PURPOSE: A method of measuring the piezoelectric coefficient of a piezoelectric thin film by using an SMPLM(Strain-Monitoring Pneumatic Loading Method) and a measuring apparatus thereof are provided to be capable of simply and exactly measuring piezoelectricity constant without using a complicated equipment. CONSTITUTION: After preparing a substrate/sample coupled body, the substrate/sample coupled body is located at the center portion of a chamber(10). At this time, the substrate/sample coupled body includes a substrate(12), the first electrode(16) formed on the upper surface of the substrate, a piezoelectric sample(14) formed at the upper portion of the resultant structure, and the second electrode(17) formed on the sample. Then, a strain gauge(18) is attached on the lower surface of the substrate. Pressure variation is measured while vertically applying pressure to the surface of the sample by supplying gas into the chamber. After measuring the electric charge variation of the sample according to the pressure variation of the two electrode, the strain variation of the sample surface is measured according to the pressure variation of the strain gauge. Then, piezoelectric constant is obtained by using the measured values.

Abstract translation: 目的：提供一种通过使用SMPLM（应变监测气动加载方法）和其测量装置来测量压电薄膜的压电系数的方法，以便能够简单且精确地测量压电常数而无需使用复杂的设备。 构成：在制备基底/样品偶联体之后，基底/样品偶联体位于室（10）的中心部分。 此时，衬底/样本耦合体包括衬底（12），在衬底的上表面上形成的第一电极（16），在所得到的结构的上部形成的压电样本（14），以及 第二电极（17）形成在样品上。 然后，将应变仪（18）附着在基板的下表面上。 通过向腔室内供应气体，在对样品表面垂直施加压力的同时测量压力变化。 根据两个电极的压力变化测量样品的电荷变化后，根据应变仪的压力变化测量样品表面的应变变化。 然后，通过使用测量值获得压电常数。

公开(公告)号：KR1020040014006A

公开(公告)日：2004-02-14

申请号：KR1020020047170

申请日：2002-08-09

Applicant: 재단법인서울대학교산학협력재단

Inventor： 장준혁 ,  정종평 ,  허성주 ,  김현이

IPC: C07K7/08

CPC classification number: C07K7/08 ,  C07K5/0806 ,  C07K5/10 ,  C07K7/06

Abstract: PURPOSE: Oligosaccharides specifically binding to hydroxyapatite are provided, which oligosaccharides are useful as linkers between biomolecules for increasing the affinity of hydroxyapatite to human body materials. CONSTITUTION: Oligosaccharides specifically binding to hydroxyapatite are provided, wherein the oligosaccharides have the amino acid sequence selected from the SEQ ID NO: 1 to SEQ ID NO: 17; the oligosaccharides are selected by screening peptides specifically binding to hydroxyapatite using peptide library; and the hydroxyapatite has similar chemical components and structure to the human bone.

Abstract translation: 目的：提供与羟基磷灰石特异性结合的寡糖，这些寡糖可用作生物分子之间的接头，用于增加羟基磷灰石与人体材料的亲和力。 提供：提供与羟基磷灰石特异性结合的寡糖，其中寡糖具有选自SEQ ID NO：1至SEQ ID NO：17的氨基酸序列; 通过使用肽文库筛选特异性结合羟基磷灰石的肽来选择寡糖; 羟基磷灰石具有与人骨相似的化学成分和结构。

公开(公告)号：KR1020030089294A

公开(公告)日：2003-11-21

申请号：KR1020020027453

申请日：2002-05-17

Applicant: 재단법인서울대학교산학협력재단

Inventor： 김현이 ,  박근태

IPC: H01L41/22 ,  G01L9/08

Abstract: PURPOSE: A method of measuring the piezoelectric coefficient of a piezoelectric thin film by using an SMPLM(Strain-Monitoring Pneumatic Loading Method) and a measuring apparatus thereof are provided to be capable of simply and exactly measuring piezoelectricity constant without using a complicated equipment. CONSTITUTION: After preparing a substrate/sample coupled body, the substrate/sample coupled body is located at the center portion of a chamber(10). At this time, the substrate/sample coupled body includes a substrate(12), the first electrode(16) formed on the upper surface of the substrate, a piezoelectric sample(14) formed at the upper portion of the resultant structure, and the second electrode(17) formed on the sample. Then, a strain gauge(18) is attached on the lower surface of the substrate. Pressure variation is measured while vertically applying pressure to the surface of the sample by supplying gas into the chamber. After measuring the electric charge variation of the sample according to the pressure variation of the two electrode, the strain variation of the sample surface is measured according to the pressure variation of the strain gauge. Then, piezoelectric constant is obtained by using the measured values.

Abstract translation: 目的：使用SMPLM（应变监测气动装载方法）测量压电薄膜的压电系数的方法及其测量装置，能够简单且精确地测量压电常数而不使用复杂的设备。 构成：在制备基板/样品耦合体之后，基板/样品耦合体位于室（10）的中心部分。 此时，基板/样品耦合体包括基板（12），形成在基板的上表面上的第一电极（16），形成在所得结构的上部的压电样品（14） 形成在样品上的第二电极（17）。 然后，在基板的下表面上附着应变仪（18）。 测量压力变化，同时通过向室中供应气体向样品表面垂直施加压力。 在根据两个电极的压力变化测量样品的电荷变化后，根据应变计的压力变化来测量样品表面的应变变化。 然后，通过使用测量值来获得压电常数。