公开(公告)号：AT203671T

公开(公告)日：2001-08-15

申请号：AT94911933

申请日：1994-03-19

Applicant: BASF AG

Inventor： TREIBER HANS-JOERG ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: C07D487/04 ,  A61K31/495 ,  A61P25/00 ,  A61P25/08 ,  A61P25/18

公开(公告)号：BG62349B2

公开(公告)日：1999-08-31

申请号：BG9860194

申请日：1994-02-28

Applicant: BASF AG

Inventor： STEINER GERD ,  UNGER LILIANE ,  BEHL BERTHOLD ,  TESCHENDORF HANS-JUERGEN

IPC: C07D401/04 ,  A61K31/40 ,  A61K31/403 ,  A61K31/4427 ,  A61K31/4433 ,  A61K31/4439 ,  A61K31/445 ,  A61P25/00 ,  A61P25/02 ,  A61P25/20 ,  A61P43/00 ,  C07D209/52 ,  C07D409/04

Abstract: The invention relates to new N-substituted derivatives of3-azabicyclo [3.2.0.] heptane with the formulawhere the substitutents of R1, R2, n and A have the meaningslisted in the description. The invention also relates to a methodfor the preparation of the compounds which are applied in medicinefor controlling diseases of the nervous system such as hypotonicsor as muscle relaxants.2 claims

公开(公告)号：CZ9900759A3

公开(公告)日：1999-06-16

申请号：CZ75999

申请日：1997-08-22

Applicant: BASF AG

Inventor： STEINER GERD ,  LUBISCH WILFRIED ,  BACH ALFRED ,  EMLING FRANZ ,  WICKE KARSTEN ,  TESCHENDORF HANS-JURGEN ,  BEHL BERTHOLD ,  CHEETHAM SHARON ,  KERRRIGAN FRANK

IPC: A61K31/519 ,  A61P25/24 ,  A61P43/00 ,  C07D211/00 ,  C07D239/00 ,  C07D333/00 ,  C07D495/14 ,  A61K31/435

CPC classification number: C07D495/14

公开(公告)号：DE59309469D1

公开(公告)日：1999-04-22

申请号：DE59309469

申请日：1993-12-06

Applicant: BASF AG

Inventor： SCHLECKER RAINER ,  TREIBER HANS-JOERG ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: C07D487/04 ,  A61K31/505 ,  A61P25/00 ,  A61P25/08 ,  A61P25/20 ,  A61P25/28

Abstract: PCT No. PCT/EP93/03424 Sec. 371 Date May 12, 1995 Sec. 102(e) Date May 12, 1995 PCT Filed Dec. 6, 1993 PCT Pub. No. WO94/13294 PCT Pub. Date Jul. 23, 1994The use of triazoloquinazolines for the production of drugs for controlling central nervous disorders is described. The triazoloquinazolines have the formula (I) where R1, R2 and X have the meanings stated in the description.

公开(公告)号：NO991132L

公开(公告)日：1999-03-09

申请号：NO991132

申请日：1999-03-09

Applicant: BASF AG

Inventor： STEINER GERD ,  LUBISCH WILFRIED ,  BACH ALFRED ,  EMLING FRANZ ,  WICKE KARSTEN ,  TESCHENDORF HANS-JUERGEN ,  BEHL BERTHOLD ,  KERRIGAN FRANK ,  CHEETHAM SHARON

IPC: A61K31/435 ,  A61K31/519 ,  A61P25/24 ,  A61P43/00 ,  C07D211/00 ,  C07D239/00 ,  C07D333/00 ,  C07D495/14 ,  C07D221/00

Abstract: A 3-substituted 3,4,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidine compound of formula IwhereinR1 is hydrogen, C1-C4-alkyl, acetyl or benzoyl, optionally substituted phenyl-C1-C4-alkyl, naphthyl-C1-C3-alkyl, phenyl-C2-C3-alkanone or a phenylcarbamoyl-C2-alkyl,R2 is optionally substituted phenyl, pyridyl, pyrimidyl or pyrazinyl, or an optionally substituted bicyclus wherein one of the two fused rings is a phenyl, a pyridyl, a pyrimidyl or a pyrazinyl ring,A is NH or oxygen,B is hydrogen or methyl,C is hydrogen, methyl or hydroxyl,X is nitrogen,Y is CH2, CH2-C2, CH2-C2-CH2 or CH2-CH,Z is nitrogen, C or CH, and the linkage between Y and Z is a single or a double bond, andn is 2, 3 or 4,or a physiologically tolerated salt thereof, and compositions comprising them and their use as antagonists of 5HT1B and 5HT1A and for the treatment of depression and related disorders.

公开(公告)号：NO991132A

公开(公告)日：1999-03-09

申请号：NO991132

申请日：1999-03-09

Applicant: BASF AG

Inventor： STEINER GERD ,  LUBISCH WILFRIED ,  BACH ALFRED ,  EMLING FRANZ ,  WICKE KARSTEN ,  TESCHENDORF HANS-JUERGEN ,  BEHL BERTHOLD ,  KERRIGAN FRANK ,  CHEETHAM SHARON

IPC: A61K31/519 ,  A61P25/24 ,  A61P43/00 ,  C07D211/00 ,  C07D239/00 ,  C07D333/00 ,  C07D495/14 ,  A61K31/435 ,  C07D221/00

CPC classification number: C07D495/14

公开(公告)号：SI9520108A

公开(公告)日：1997-10-31

申请号：SI9520108

申请日：1995-09-19

Applicant: BASF AG

Inventor： TREIBER HANS-JOERG ,  LUBISCH WILFRIED ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P9/00 ,  A61P25/00 ,  A61P25/08 ,  A61P25/24 ,  A61P25/26 ,  C07D487/04

公开(公告)号：DE59307217D1

公开(公告)日：1997-10-02

申请号：DE59307217

申请日：1993-06-08

Applicant: BASF AG

Inventor： STEINER GERD ,  UNGER LILIANE ,  BEHL BERTHOLD ,  TESCHENDORF HANS-JUERGEN ,  MUNSCHAUER RAINER

IPC: C07D513/04 ,  A61K20060101 ,  A61K31/33 ,  A61K31/395 ,  A61K31/40 ,  A61K31/4045 ,  A61K31/4184 ,  A61K31/505 ,  A61K31/506 ,  A61K31/513 ,  A61K31/517 ,  A61K31/519 ,  A61K31/54 ,  A61K31/542 ,  A61P25/00 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P43/00 ,  C07D20060101 ,  C07D207/00 ,  C07D209/02 ,  C07D209/52 ,  C07D221/00 ,  C07D239/00 ,  C07D401/04 ,  C07D401/06 ,  C07D401/14 ,  C07D403/00 ,  C07D403/04 ,  C07D403/06 ,  C07D403/14 ,  C07D409/04 ,  C07D409/06 ,  C07D409/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D495/04

Abstract: PCT No. PCT/EP93/01438 Sec. 371 Date Dec. 16, 1994 Sec. 102(e) Date Dec. 16, 1994 PCT Filed Jun. 8, 1993 PCT Pub. No. WO94/00458 PCT Pub. Date Jan. 6, 1994.Abstract of the Disclosure: Compounds of the formula I I where R1, R2, n , R3, A, X, Y and Z have the meanings stated in the description, and the preparation thereof are described. The novel compounds are suitable for controlling diseases , i.e., as neuroleptics, antidepressants, sedatives, hypnotics, CNS protectives or muscle relaxants.

公开(公告)号：HUT76472A

公开(公告)日：1997-09-29

申请号：HU9603544

申请日：1995-06-16

Applicant: BASF AG

Inventor： BEHL BERTHOLD ,  HOFMANN HANS PETER ,  LUBISCH WILFRIED

IPC: C07D241/44 ,  A61K31/495 ,  A61P25/00 ,  A61P25/08 ,  A61P25/24 ,  A61P25/26 ,  C07D20060101 ,  C07D241/54 ,  C07D403/04

Abstract: PCT No. PCT/EP95/02324 Sec. 371 Date Dec. 20, 1996 Sec. 102(e) Date Dec. 20, 1996 PCT Filed Jun. 16, 1995 PCT Pub. No. WO95/35289 PCT Pub. Date Dec. 28, 1995Novel amido-quinoxalinediones of the formula I where R1-R5, n and m have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases.

公开(公告)号：HRP950339A2

公开(公告)日：1997-08-31

申请号：HRP950339

申请日：1995-06-15

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: C07D241/44 ,  A61K31/495 ,  A61P25/00 ,  A61P25/08 ,  A61P25/24 ,  A61P25/26 ,  C07D20060101 ,  C07D241/54 ,  C07D403/04

Abstract: PCT No. PCT/EP95/02324 Sec. 371 Date Dec. 20, 1996 Sec. 102(e) Date Dec. 20, 1996 PCT Filed Jun. 16, 1995 PCT Pub. No. WO95/35289 PCT Pub. Date Dec. 28, 1995Novel amido-quinoxalinediones of the formula I where R1-R5, n and m have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases.