公开(公告)号：HU0201551A2

公开(公告)日：2002-08-28

申请号：HU0201551

申请日：2000-02-14

Applicant: BASF AG

Inventor： KAMESWARAN VENKATARAMAN

IPC: C07D239/46 ,  C07B61/00 ,  C07D239/54 ,  C07D261/20 ,  C07D275/04 ,  C07D417/04

公开(公告)号：AU1041702A

公开(公告)日：2002-01-30

申请号：AU1041702

申请日：2001-07-13

Applicant: BASF AG

Inventor： PEDERSEN MARIANNE K ,  BIRK IWANA T ,  ORTH ANN B ,  SINGH BIJAY K ,  TECLE BERHANE ,  KAMESWARAN VENKATARAMAN ,  SZUCES STEPHEN S

IPC: A01N43/56 ,  C07D231/20 ,  C07D231/32 ,  C07D401/12 ,  C07D409/12 ,  G01N33/50 ,  C12Q1/00

Abstract: This invention relates to a method for identifying compounds that specifically inhibit a metabolic target site or pathway in plants. Enzymes which are specifically affected by the method of the invention include plant pyrimidine biosynthetic pathway enzymes, and particularly the enzymes involved in the conversion of orotate to uridine-5'-monophosphate (UMP). Further, the invention relates to a method for control of undesirable monocotyledenous and dicotyledenous plant species.

公开(公告)号：DE69802636D1

公开(公告)日：2002-01-10

申请号：DE69802636

申请日：1998-09-01

Applicant: BASF AG

Inventor： KAMESWARAN VENKATARAMAN

IPC: C07D239/52 ,  C07D401/12 ,  C07D403/12 ,  C07D413/12 ,  C07D417/12

Abstract: Preparation of an unsymmetrical 4,6-bis(aryloxy)pyrimidine derivatives of formula (I) is new. The process comprises reacting a 4-halo-6-(aryloxy)pyrimidine compound of formula (II) with >=1 molar equivalent of a 1-4C trialkylamine, a 5-14 membered unsaturated heterocyclic amine optionally substituted to 1-3 1-4C alkyl, or 1-4C alkoxy groups in the presence of an aromatic hydrocarbon and/or a halogenated aromatic hydrocarbon solvents, to form an ammonium halide of formula (III), and reacting the ammonium halide with >=1 phenyl compound of formula (IV) and a base. R1, R8 = H or halo; R1, R7 = H halo, CN, NO2 alkyl, haloalkyl, alkoxy, alkylthio, amino, alkylamino, dialkylamino, alkoxyalkyl, haloalkoxyalkyl or alkoxycarbonyl; R2, R6 = H, halo, alkyl, haloalkyl, haloalkoxy, haloalkoxyalkyl, alkoxycarbonyl, haloalkoxycarbonyl, haloalkylsulphinyl, haloalkylsulphonyl, nitro, or cyano; R3, R5 = H, halo, alkyl or alkoxy; and R4 = H, cyano, alkyl, haloalkyl, alkoxy, alkylthio, alkylsulphinyl, or phenyl; provided that >= 1 of R2 and R6 is not H, and that the aryloxy groups are different. Q = R10N(R9)(R11) or substituted heteroaryl groups of formulae (a)-(g). R9, R10, R11 = 1-4C alkyl, or R910 = 5-6 membered ring with 3-5 O, S or NR-14 atoms; R11 = 1-4C alkyl; Z = O, S or NR14; R12, R13 = H, 1-4C alkyl, 1-4C alkoxy; or R12, R13 = 5-6 membered saturated or unsaturated ring optionally interrupted with O, S, or NR14, and optionally substituted with 1-3 1-4C alkyl or 1-4C alkoxy groups; and R14 = 1-4C alkyl.