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    COMPOSITION WITH ZINC AMINO ACID/TRIMETHYLGLYCINE HALIDE PRECURSORS
    45.
    发明申请
    COMPOSITION WITH ZINC AMINO ACID/TRIMETHYLGLYCINE HALIDE PRECURSORS 审中-公开
    与ZINC氨基酸/三甲基胆碱盐酸盐前体的组合物

    公开(公告)号：WO2014098814A1

    公开(公告)日：2014-06-26

    申请号：PCT/US2012/070492

    申请日：2012-12-19

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： PAN, Long ,  MATTAI, Jairajh ,  ANSARI, Shamim ,  QIU, Jianhong ,  MASTERS, James, G. ,  YANG, Ying

    IPC: A61K8/27 ,  A61K8/44 ,  A61Q15/00

    CPC classification number: A61K8/27 ,  A61K8/20 ,  A61K8/44 ,  A61K2800/58 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/00 ,  A61Q19/10

    Abstract: A personal care composition for application to the skin or hair comprising a cosmetically acceptable carrier and zinc X halide precursors wherein the precursors are a zinc ion source, an X source, and a halide source, wherein the halide source can be part of the zinc ion source, the X source, or a halogen acid, wherein the precursors can complex into the zinc X halide when the composition is applied to the skin or hair, wherein X is an amino acid or trimethylglycine. Methods of making and using the compositions are also provided. When the precursors complex into a zinc X halide, the complex can be used to deliver zinc salts to block perspiration and provide antibacterial effects.

    Abstract translation: 一种用于皮肤或毛发的个人护理组合物，其包含美容上可接受的载体和锌X卤化物前体，其中前体是锌离子源，X源和卤化物源，其中卤化物源可以是锌离子的一部分 源，X源或卤素酸，其中当将组合物施用于皮肤或毛发时，前体可以复合成锌X卤化物，其中X是氨基酸或三甲基甘氨酸。 还提供了制备和使用组合物的方法。 当前体复合成锌X卤化物时，该配合物可用于递送锌盐以阻止汗水并提供抗菌效果。

    OXO-HEXAMERIC ZIRCONIUM-OCTAAMINO ACID ANTIPERSPIRANT SALTS
    47.
    发明申请
    OXO-HEXAMERIC ZIRCONIUM-OCTAAMINO ACID ANTIPERSPIRANT SALTS 审中-公开
    OXO-HEXAMERIC ZIRCONIUM-OCTAAMINO ACID抗感染剂

    公开(公告)号：WO2009039030A1

    公开(公告)日：2009-03-26

    申请号：PCT/US2008/076105

    申请日：2008-09-12

    Applicant: COLGATE-PALMOLIVE COMPANY ,  PAN, Long ,  KILPATRICK, Latonya ,  TANG, Xiaozhong

    Inventor： PAN, Long ,  KILPATRICK, Latonya ,  TANG, Xiaozhong

    IPC: A61K8/26 ,  A61K8/28 ,  A61K8/44 ,  A61Q15/00 ,  C07F7/00

    CPC classification number: C07F7/006 ,  A61K8/28 ,  A61K8/44 ,  A61K2800/58 ,  A61Q15/00

    Abstract: A process for preparing oxo-hexameric zirconium-octaamino acid, such as glycine, salt comprising: mixing zirconium (Zr): amino acid : and mineral acid, in a molar ratio of 1 : about 1 to about 15: about 1.5 to about 3 to form a mixture; optionally, filtering the mixture; and optionally, drying the mixture. An oxo-hexameric zirconium-octaamino acid salt of the molecular formula: oxo- [Zr 6 Amino Acid 8 ]•X y • nH 2 O, wherein Zr is zirconium, X is an anion of a mineral acid, and n and y are numerical values from 0 to 20. A method of making an antiperspirant active zirconium-aluminum-amino acid compound comprising mixing an oxo- hexameric zirconium-octaamino acid salt with aluminum chlorohydrex and/or aluminum chloride, and drying the mixture. The smallest oxo-hexameric zirconium-octaamino acid salt of this invention provides stability, efficacy, and shelf life of zirconium-amino acid species for formulations in antiperspirant and/or deodorant compositions.

    Abstract translation: 一种制备氧代 - 六聚锆 - 八氨基酸如甘氨酸盐的方法，包括：将锆（Zr）：氨基酸和无机酸以摩尔比1：约1：约15：约1.5至3 形成混合物 任选地，过滤混合物; 并任选地干燥混合物。 分子式为氧代 - [Zr 6氨基酸8] Xy nH 2 O的氧代 - 六聚体 - 八 - 八烷基酸盐，其中Zr为锆，X为无机酸的阴离子，n和y为0至20的数值。 一种制备止汗活性锆 - 铝 - 氨基酸化合物的方法，包括将氧代六聚体锆 - 八氨基酸盐与氯化铝和/或氯化铝混合，并干燥该混合物。 本发明的最小的氧代 - 六聚体锆 - 八氨基酸盐为止汗剂和/或除臭剂组合物中的制剂提供了锆 - 氨基酸种类的稳定性，有效性和保质期。

    METHODS FOR MEASURING PH USINF NMR METHODS
    49.
    发明申请
    METHODS FOR MEASURING PH USINF NMR METHODS 审中-公开

    公开(公告)号：WO2020123244A1

    公开(公告)日：2020-06-18

    申请号：PCT/US2019/064581

    申请日：2019-12-05

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： CHENG, Chi-Yuan ,  HAO, Zhigang ,  PAN, Long ,  BALSANDORJ, Zolijargal

    IPC: G01N24/08 ,  G01N33/02 ,  G01N33/15 ,  G01R33/48

    Abstract: Methods for measuring pH of gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, are provided. The method may include preparing a calibration curve of a chemical species including or having an acid dissociation constant. Preparing the calibration curve may include plotting a chemical shift of the chemical species relative to pH. The method may also include determining a chemical shift of a gel, paste, and colloid, aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, including the chemical species. The method may further include determining the pH of the gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, with the chemical shift of the product and the calibration curve.

    SOLID CLEANSING COMPOSITIONS WITH TAURINE AND METHODS THEREOF
    50.
    发明申请
    SOLID CLEANSING COMPOSITIONS WITH TAURINE AND METHODS THEREOF 审中-公开
    牛磺酸固体清洁组合物及其方法

    公开(公告)号：WO2018030983A1

    公开(公告)日：2018-02-15

    申请号：PCT/US2016/046012

    申请日：2016-08-08

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： SMART, Scott ,  PAN, Long

    IPC: A61K8/42 ,  A61K8/46 ,  A61Q19/10 ,  C11D17/00 ,  A61K8/02

    Abstract: A solid liquid cleansing composition and methods of preparing the same are disclosed. The solid cleansing composition may include a soap and an ionic liquid. The soap may be a sodium soap, an ammonium soap, a potassium soap, a magnesium soap, a calcium soap, or a combination thereof. The ionic liquid may include a base, taurine, and/or water.

    Abstract translation: 公开了一种固体液体清洁组合物及其制备方法。 该固体清洁组合物可以包括肥皂和离子液体。 肥皂可以是钠皂，铵皂，钾皂，镁皂，钙皂或其组合。 离子液体可以包括碱，牛磺酸和/或水。

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