公开(公告)号：DK0808816T3

公开(公告)日：2001-01-22

申请号：DK97105752

申请日：1997-04-08

Applicant: DEGUSSA

Inventor： HAHN RAINER DR ,  HUTHMACHER KLAUS DR ,  HUEBNER FRANK DR ,  KRILL STEFFEN DR ,  GORA ULRICH

IPC: B01J31/22 ,  C07B61/00 ,  C07C45/34 ,  C07C49/603

Abstract: Preparation of 3,5,5-trimethylcyclohex-2-en-1,4-dione (I) comprises oxidation of 3,5,5-trimethylcyclohex-3-en-1-one (II) by molecular oxygen in the presence of manganese (salen) or its derivatives as catalyst, an alkylamine and water in an inert solvent in the presence of another catalytic compound X where X = an organic acid with pKa of 2-7, or 1-4C aliphatic alcohol, or phenol, or compounds where an enolic structure is possible, where X is present in a molar ratio of 1:1 to 100:1 with the catalyst and (II) is >15wt.% of the total.

公开(公告)号：IN185169B

公开(公告)日：2000-12-02

申请号：IN2182CA1998

申请日：1998-12-16

Applicant: DEGUSSA

Inventor： KRILL STEFFEN DR ,  HUBNER FRANK DR ,  HAHN RAINER DR ,  WEIGEL HORST ,  HUTHMACHER KLAUS DR

IPC: C07B61/00 ,  C07D311/72 ,  A61K31/34 ,  C07D307/78

Abstract: Preparation of alpha -tocopherol ester compounds (I) involves reacting a hydroquinone ester (II) with an allyl alcohol derivative (III) in presence of a zinc halide and an acid. Preparation of alpha -tocopherol esters (or derivatives or homologues) of formula (I) involves reacting a hydroquinone mono- (sic) or diester of formula (II) with an allyl alcohol derivative of formula (III) in presence of a zinc halide and a protonic acid at 25-100 degrees C. R1, R2 = optionally unsaturated 1-20C alkyl; R3-R5 = H or 1-3C alkyl; n = 0-5; Q = -C(Me)=CH-CH2L or -C(Me)(L')-CH=CH2; L = OH, halo, acetoxy, MeSO2O, EtSO2O, PhSO2O or toluenesulfonyl; L' = OH, halo or acetoxy.

公开(公告)号：DE19639569A1

公开(公告)日：1998-04-02

申请号：DE19639569

申请日：1996-09-26

Applicant: DEGUSSA

Inventor： KRILL STEFFEN DR ,  GIRAY GUENES ,  HUTHMACHER KLAUS DR ,  HUEBNER FRANK DR ,  TANNER HERBERT

IPC: B01J23/02 ,  B01J23/75 ,  B01J23/755 ,  C07B61/00 ,  C07C45/67 ,  C07C45/82 ,  C07C45/83 ,  C07C49/603

公开(公告)号：DE19619570A1

公开(公告)日：1997-11-20

申请号：DE19619570

申请日：1996-05-15

Applicant: DEGUSSA

Inventor： HAHN RAINER DR ,  GORA ULRICH ,  HUTHMACHER KLAUS DR ,  HUEBNER FRANK DR ,  KRILL STEFFEN DR

IPC: B01J31/22 ,  C07B61/00 ,  C07C45/34 ,  C07C49/603

Abstract: Preparation of 3,5,5-trimethylcyclohex-2-en-1,4-dione (I) comprises oxidation of 3,5,5-trimethylcyclohex-3-en-1-one (II) by molecular oxygen in the presence of manganese (salen) or its derivatives as catalyst, an alkylamine and water in an inert solvent in the presence of another catalytic compound X where X = an organic acid with pKa of 2-7, or 1-4C aliphatic alcohol, or phenol, or compounds where an enolic structure is possible, where X is present in a molar ratio of 1:1 to 100:1 with the catalyst and (II) is >15wt.% of the total.