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    42.
    发明专利
    未知

    公开(公告)号：DK167152B1

    公开(公告)日：1993-09-06

    申请号：DK594884

    申请日：1984-12-12

    Applicant: HOECHST AG

    Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

    IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543

    Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

    50.
    发明专利
    未知

    公开(公告)号：NO844994L

    公开(公告)日：1985-06-14

    申请号：NO844994

    申请日：1984-12-12

    Applicant: HOECHST AG

    Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

    IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543 ,  C08F

    Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

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