公开(公告)号：FI85028B

公开(公告)日：1991-11-15

申请号：FI844889

申请日：1984-12-11

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543

Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

公开(公告)号：CA1241146A

公开(公告)日：1988-08-23

申请号：CA469966

申请日：1984-12-12

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543

Abstract: HOE 83/F 264 of the disclosure: The invention relates to crosslinked polymers based on polyvinyl acylate or polyvinyl alcohol and having crosslinking agent units which are derived from crosslinking agents of the general formulae (I) and/or (II) These products, inter alia, are particularly hydrolysisresistant and can have high crosslinking densities. The invention also relates to a process for preparing these polymers and to their use in chromatography and as carriers for biologically active substances.

公开(公告)号：AU569353B2

公开(公告)日：1988-01-28

申请号：AU3657384

申请日：1984-12-12

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543

Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

公开(公告)号：AU3657384A

公开(公告)日：1985-06-20

申请号：AU3657384

申请日：1984-12-12

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543

Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

公开(公告)号：FI844889L

公开(公告)日：1985-06-14

申请号：FI844889

申请日：1984-12-11

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543 ,  C08F

Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

公开(公告)号：DK594884A

公开(公告)日：1985-06-14

申请号：DK594884

申请日：1984-12-12

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543 ,  C08F ,  B01D

Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

公开(公告)号：DK167152B1

公开(公告)日：1993-09-06

申请号：DK594884

申请日：1984-12-12

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543

Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

公开(公告)号：NO844994L

公开(公告)日：1985-06-14

申请号：NO844994

申请日：1984-12-12

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543 ,  C08F

Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

公开(公告)号：NO166188C

公开(公告)日：1991-06-12

申请号：NO844994

申请日：1984-12-12

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543

Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.

公开(公告)号：NO166188B

公开(公告)日：1991-03-04

申请号：NO844994

申请日：1984-12-12

Applicant: HOECHST AG

Inventor： MAUZ OTTO ,  NOETZEL SIEGFRIED ,  NEUMANN BERNHARD

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543

Abstract: For the contracting states : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A crosslinked polymer in the form of beads which substantially comprises vinyl acylate units and units of a crosslinking agent which has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, the amount of theses crosslinking agent units accounting for 1 to 60 % by weight of the polymer, the acyloxy groups of the vinyl acylate units being present as such or having been partially or completely replaced by hydroxyl groups, and the average particle size of the beads being 20 to 800 mu m and the mean pore diameter being 2 to 10,000 nm. For the contracting state AT 1. A process for preparing a crosslinked polymer in the form of beads by copolymerizing vinyl acylate with a crosslinking agent and, if propriate, a further monomer copolymerizable with the vinyl acylate in ther presence of a dispersion medium and if desired partially or completely hydrolyzing the resulting polymer, wherein the crosslinking agent has the formulae see diagramm : EP0150350,P12,F1 and/or see diagramm : EP0150350,P12,F2 where R1 and R2 in the formula (I) can be identical or different and each denotes vinyl-, 1-acyloxyvinyl, allyl- or 2-acyloxyallyl, A represents a divalent hydrocarbon radical of 2 to 8 carbon atoms, B in the formula (II) stands for a divalent hydrocarbon radical of 1 to 8 carbon atoms and X denotes acyloxy, and the beads obtained have an average particle size of 10 to 800 mu m and an average pore diameter of 2 to 10,000 nm.