公开(公告)号：US5965388A

公开(公告)日：1999-10-12

申请号：US721488

申请日：1996-09-27

Applicant: Kenneth Jacobs ,  John M. McCoy ,  Edward R. LaVallie ,  Lisa A. Racie ,  David Merberg ,  Maurice Treacy ,  Cheryl Evans ,  Michael Bowman

Inventor： Kenneth Jacobs ,  John M. McCoy ,  Edward R. LaVallie ,  Lisa A. Racie ,  David Merberg ,  Maurice Treacy ,  Cheryl Evans ,  Michael Bowman

IPC: C12N15/09 ,  A61K31/711 ,  A61K38/00 ,  A61K48/00 ,  A61P1/02 ,  A61P7/00 ,  A61P11/06 ,  A61P19/00 ,  A61P21/04 ,  A61P25/00 ,  A61P29/00 ,  A61P31/00 ,  A61P35/00 ,  C07K14/47 ,  C12N5/10 ,  C12N15/12 ,  C12P21/02 ,  C12Q1/68 ,  C12N15/00

CPC classification number: C07K14/47

Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.

公开(公告)号：US5958726A

公开(公告)日：1999-09-28

申请号：US867680

申请日：1997-06-02

Applicant: Kenneth Jacobs ,  John M. McCoy ,  Lisa A. Racie ,  Edward R. LaVallie ,  David Merberg ,  Maurice Treacy ,  Cheryl Evans

Inventor： Kenneth Jacobs ,  John M. McCoy ,  Lisa A. Racie ,  Edward R. LaVallie ,  David Merberg ,  Maurice Treacy ,  Cheryl Evans

IPC: C12N15/09 ,  A61K31/00 ,  A61K38/00 ,  A61K48/00 ,  A61P7/00 ,  A61P29/00 ,  A61P29/02 ,  A61P35/00 ,  A61P37/00 ,  A61P37/04 ,  A61P37/06 ,  A61P43/00 ,  C07K14/47 ,  C07K14/52 ,  C12N1/19 ,  C12N1/21 ,  C12N5/00 ,  C12N5/10 ,  C12N15/00 ,  C12R1/91

CPC classification number: C07K14/47

Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.

公开(公告)号：US5927017A

公开(公告)日：1999-07-27

申请号：US16871

申请日：1998-01-30

Applicant: Kenneth Jacobs ,  Auguste Joseph Menard

Inventor： Kenneth Jacobs ,  Auguste Joseph Menard

IPC: E05D13/00

CPC classification number: E05D15/0673 ,  E05Y2201/614 ,  E05Y2900/132 ,  Y10T16/379

Abstract: A roller assembly for a sliding door that slides along a track includes an anti-jump member engageable with the track to prevent the roller assembly from derailing. The roller assembly comprises a bracket adapted for attachment to the door, a roller mounting member slidably seated in the bracket, and a roller rotatably mounted on the roller mounting member for travel along the track. The anti-jump member is pivotably supported in and displaceably carried by the roller mounting member for movement between an extended operative position wherein an engagement portion on the lower end thereof rides in the track, and a retracted inoperative position, wherein the engagement portion is spaced upwardly from the track. The roller assembly is operable to slide the door with the anti-jump member in either the operative position or the retracted position.

Abstract translation: 用于沿着轨道滑动的滑动门的滚子组件包括可与轨道接合的防跳转构件，以防止滚子组件脱轨。 辊组件包括适于附接到门的支架，可滑动地安置在支架中的滚子安装构件，以及可旋转地安装在滚子安装构件上以沿着轨道行进的滚子。 所述防跳动构件可枢转地支撑在所述滚子安装构件中并且可移动地承载在所述滚子安装构件上，用于在其下端的接合部分在所述轨道中移动的延伸操作位置和缩回的非操作位置之间移动，其中所述接合部分间隔开 从轨道向上​​。 辊组件可操作以使防滑部件在操作位置或缩回位置滑动。

公开(公告)号：US5807709A

公开(公告)日：1998-09-15

申请号：US721798

申请日：1996-09-27

Applicant: Kenneth Jacobs ,  John M. McCoy ,  Edward R. LaVallie ,  Lisa A. Racie ,  David Merberg ,  Maurice Treacy ,  Vikki Spaulding

Inventor： Kenneth Jacobs ,  John M. McCoy ,  Edward R. LaVallie ,  Lisa A. Racie ,  David Merberg ,  Maurice Treacy ,  Vikki Spaulding

IPC: C12N15/09 ,  A61K31/00 ,  A61K38/00 ,  A61P37/00 ,  A61P37/02 ,  C07K14/47 ,  C07K14/52 ,  C12N5/10 ,  C12N15/12 ,  C12P21/02 ,  C12N15/00

CPC classification number: C07K14/52 ,  C07K14/47 ,  A61K38/00

Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.

公开(公告)号：US5708157A

公开(公告)日：1998-01-13

申请号：US686878

申请日：1996-07-26

Applicant: Kenneth Jacobs ,  John M. McCoy ,  Edward R. LaVallie ,  Lisa A. Racie ,  David Merberg ,  Maurice Treacy ,  Cheryl Evans ,  Vikki Spaulding

Inventor： Kenneth Jacobs ,  John M. McCoy ,  Edward R. LaVallie ,  Lisa A. Racie ,  David Merberg ,  Maurice Treacy ,  Cheryl Evans ,  Vikki Spaulding

IPC: C12N15/09 ,  A61K38/00 ,  A61K48/00 ,  A61P3/02 ,  A61P7/02 ,  A61P7/08 ,  A61P35/00 ,  A61P37/00 ,  C07K14/47 ,  C12N5/10 ,  C12N15/12 ,  C12P21/02 ,  C12N15/10

CPC classification number: C07K14/47 ,  Y10S530/85 ,  Y10S530/851

Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.

公开(公告)号：US5536637A

公开(公告)日：1996-07-16

申请号：US328962

申请日：1994-10-24

Applicant: Kenneth Jacobs

Inventor： Kenneth Jacobs

IPC: C07K14/52 ,  C12N9/26 ,  C12N15/10 ,  C12Q1/68

CPC classification number: C12N15/1051 ,  C07K14/52 ,  C12N9/2408

Abstract: A novel method of screening for novel secreted mammalian proteins is described in which mammalian secretory leader sequences are detected using the yeast invertase gene as a reporter system.

Abstract translation: 描述了筛选新型分泌的哺乳动物蛋白质的新方法，其中使用酵母转化酶基因作为报告系统检测哺乳动物分泌前导序列。

公开(公告)号：US08048984B2

公开(公告)日：2011-11-01

申请号：US12292965

申请日：2008-12-01

Applicant: Kenneth Jacobs ,  Lynette Fouser ,  Vikki Spaulding ,  Dejun Xuan

Inventor： Kenneth Jacobs ,  Lynette Fouser ,  Vikki Spaulding ,  Dejun Xuan

IPC: C07K1/00 ,  C07K2/00 ,  C07K4/00 ,  C07K5/00 ,  C07K7/00 ,  C07K14/00 ,  C07K16/00 ,  C07K17/00 ,  A61K38/00

CPC classification number: C07K14/5428 ,  A61K38/00 ,  A61K2039/505

Abstract: Novel human GIL-19/AE289 protein is disclosed which shows a high degree of homology to interleukin-10 (IL-10). Polynucleotides encoding such protein are also enclosed.

Abstract translation: 公开了与白细胞介素-10（IL-10）高度同源的新型人GIL-19 / AE289蛋白。 编码这种蛋白质的多核苷酸也被封闭。

公开(公告)号：US20110262390A1

公开(公告)日：2011-10-27

申请号：US13113552

申请日：2011-05-23

Applicant: Kenneth Jacobs ,  Debra D. Pittman ,  Lynette Fouser ,  Vikki Spaulding ,  Dejun Xuan

Inventor： Kenneth Jacobs ,  Debra D. Pittman ,  Lynette Fouser ,  Vikki Spaulding ,  Dejun Xuan

IPC: A61K38/20 ,  A61P29/00

CPC classification number: C07K16/244 ,  A61K38/20 ,  A61K2039/505 ,  C07K14/54 ,  C07K14/5428 ,  C07K2317/76 ,  C12N2799/022 ,  A61K2300/00

Abstract: Inhibitors of IL-22 are disclosed as well as pharmaceutical compositions and methods of using same. The inhibitors include IL-22 antibodies and are useful for treating inflammatory disorders.

Abstract translation: 公开了IL-22的抑制剂以及药物组合物及其使用方法。 抑制剂包括IL-22抗体，可用于治疗炎症性疾病。

公开(公告)号：US07951372B1

公开(公告)日：2011-05-31

申请号：US11896363

申请日：2007-08-31

Applicant: Kenneth Jacobs ,  Debra D. Pittman ,  Lynette Fouser ,  Vikki Spaulding ,  Dejun Xuan

Inventor： Kenneth Jacobs ,  Debra D. Pittman ,  Lynette Fouser ,  Vikki Spaulding ,  Dejun Xuan

IPC: A61K39/395 ,  A61K39/00

CPC classification number: C07K16/244 ,  A61K38/20 ,  A61K2039/505 ,  C07K14/54 ,  C07K14/5428 ,  C07K2317/76 ,  C12N2799/022 ,  A61K2300/00

Abstract: Inhibitors of IL-22 are disclosed as well as pharmaceutical compositions and methods of using same. The inhibitors include IL-22 antibodies and are useful for treating inflammatory disorders.

Abstract translation: 公开了IL-22的抑制剂以及药物组合物及其使用方法。 抑制剂包括IL-22抗体，可用于治疗炎症性疾病。

公开(公告)号：US07361738B2

公开(公告)日：2008-04-22

申请号：US11169232

申请日：2005-06-28

Applicant: Katherine Turner ,  Steven C. Clark ,  Kenneth Jacobs ,  Rodney M. Hewick ,  Thomas G. Gesner

Inventor： Katherine Turner ,  Steven C. Clark ,  Kenneth Jacobs ,  Rodney M. Hewick ,  Thomas G. Gesner

IPC: C07K14/47 ,  C12N15/10 ,  C12P21/02

CPC classification number: C07K14/53 ,  A61K38/00

Abstract: Novel polypeptides of human megakaryocyte stimulating factors (MSFs). Pharmaceutical compositions containing same, and methods for their preparation and use are provided.

Abstract translation: 人类巨核细胞刺激因子（MSF）的新型多肽。 提供含有其的药物组合物及其制备和使用方法。