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公开(公告)号：DK1945632T3
公开(公告)日：2013-12-16
申请号：DK06837028
申请日：2006-11-08
Applicant: VERTEX PHARMA
Inventor： HADIDA RUAH SARA , HAMILTON MATTHEW , MILLER MARK , GROOTENHUIS PETER D J , BEAR BRIAN , MCCARTHY JASON , ZHOU JINGLAN
IPC: C07D405/12 , A61K31/4418 , A61K31/5585 , A61P11/00 , C07D213/75 , C07D405/14
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42.发明专利
公开(公告)号：DK2404919T3
公开(公告)日：2013-11-04
申请号：DK10191575
申请日：2006-11-08
Applicant: VERTEX PHARMA
Inventor： HADIDDA RUAH SARA , HAMILTON MATTHEW , MILLER MARK , GROOTENHUIS PETER D J , BEAR BRIAN , MCCARTHY JASON , ZHOU JINGLAN
IPC: C07D405/12 , A61K31/443 , A61P11/00
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公开(公告)号：AU2012202579A1
公开(公告)日：2012-05-24
申请号：AU2012202579
申请日：2012-05-02
Applicant: VERTEX PHARMA
Inventor： RUAH SARA HADIDA , HAMILTON MATTHEW , MILLER MARK , GROOTENHUIS PETER D J , BEAR BRIAN , MCCARTHY JASON , ZHOU JINGLAN
IPC: C07D405/12 , A61K31/4418 , A61K31/5585 , A61P11/00 , C07D213/75 , C07D405/14
Abstract: Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
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公开(公告)号：AU2012201325B2
公开(公告)日：2012-05-03
申请号：AU2012201325
申请日：2012-03-05
Applicant: VERTEX PHARMA
Inventor： RUAH SARA HADIDA , HAMILTON MATTHEW , MILLER MARK , GROOTENHUIS PETER D J , BEAR BRIAN , MCCARTHY JASON , ZHOU JINGLAN
IPC: C07D405/12 , A61K31/4418 , A61K31/5585 , A61P11/00 , C07D213/75 , C07D405/14
Abstract: Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
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公开(公告)号：DE602004022319D1
公开(公告)日：2009-09-10
申请号：DE602004022319
申请日：2004-11-15
Applicant: VERTEX PHARMA
Inventor： HADIDA RUAH SARAH S , MILLER MARK T , GROOTENHUIS PETER D , HAMILTON MATTHEW
IPC: A61K31/42 , A61K31/422 , A61K31/426 , A61K31/427 , C07D263/34 , C07D277/56 , C07D417/04 , C07D417/06 , C07D417/12
Abstract: The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
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Patent Agency Ranking
公开(公告)号：NO20082674A
公开(公告)日：2008-08-07
申请号：NO20082674
申请日：2008-06-09
Applicant: VERTEX PHARMA
Inventor： BEAR BRIAN , GROOTENHUIS PETER D J , HAMILTON MATTHEW , RUAH SARA HADIDA , ZHOU JINGLAN , MILLER MARK , MCCARTHY JASON
IPC: C07D405/12 , A61K31/443 , A61K31/497 , C07D405/14
CPC classification number: C07D405/12 , A61K31/443 , A61K31/444 , A61K31/4545 , A61K31/47 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D405/14
Abstract: Pharmaceutically acceptable compositions of the present invention are useful as modulators of ATP-Binding Cassette ("ABC") transporters of fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR").
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公开(公告)号：ZA200604578B
公开(公告)日：2008-05-28
申请号：ZA200604578
申请日：2004-11-15
Applicant: VERTEX PHARMA
Inventor： HADIDA RUAH SARAH S , MILLER MARK T , GROOTENHUIS PETER D J , HAMILTON MATTHEW
IPC: A61K20090101 , A61K31/42 , A61K31/422 , A61K31/426 , A61K31/427 , C07D20090101 , C07D263/34 , C07D277/56 , C07D417/04 , C07D417/06 , C07D417/12
Abstract: The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
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公开(公告)号：BRPI0507278A
公开(公告)日：2007-06-26
申请号：BRPI0507278
申请日：2005-01-31
Applicant: VERTEX PHARMA
Inventor： RUAH SARAH S HADIDA , GROOTENHUIS PETER D J , MILLER MARK T , HAMILTON MATTHEW
IPC: C07D231/40 , C07D233/88 , C07D263/48 , C07D271/10 , C07D271/113 , C07D277/46 , C07D277/54 , C07D277/82 , C07D285/12 , C07D285/135 , C07D405/12 , C07D407/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D493/10
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公开(公告)号：AU2006311650A1
公开(公告)日：2007-05-18
申请号：AU2006311650
申请日：2006-11-08
Applicant: VERTEX PHARMA
Inventor： MILLER MARK , MCCARTHY JASON , BEAR BRIAN , ZHOU JINGLAN , HAMILTON MATTHEW , RUAH SARA HADIDA , GROOTENHUIS PETER D J
IPC: C07D405/12 , A61K31/4418 , A61K31/5585 , A61P11/00 , C07D213/75 , C07D405/14
Abstract: Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention..
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公开(公告)号：CA2545719A1
公开(公告)日：2005-06-02
申请号：CA2545719
申请日：2004-11-15
Applicant: VERTEX PHARMA
Inventor： HAMILTON MATTHEW , HADIDA RUAH SARAH S , GROOTENHUIS PETER D J , MILLER MARK T
IPC: A61K31/42 , A61K31/422 , A61K31/426 , A61K31/427 , C07D263/34 , C07D277/56 , C07D417/04 , C07D417/06 , C07D417/12
Abstract: The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
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