High-speed, rugged, time-resolved, Raman spectrometer for sensing multiple components of a sample and for diagnostics of pathological skin conditions such as cancer
    46.
    发明授权
    High-speed, rugged, time-resolved, Raman spectrometer for sensing multiple components of a sample and for diagnostics of pathological skin conditions such as cancer 有权
    高速,坚固,时间分辨的拉曼光谱仪,用于感测样品的多个组分,并诊断病理性皮肤病症如癌症

    公开(公告)号:US07944555B2

    公开(公告)日:2011-05-17

    申请号:US12551404

    申请日:2009-08-31

    Applicant: Ricardo Claps

    Inventor: Ricardo Claps

    Abstract: A new architecture for implementing a time-resolved Raman spectrometer is 2-3 orders of magnitude faster than current systems. In one embodiment, the invention employs a rotating optical switch to time multiplex an input signal through multiple band-pass filters and into a single optical detector which is electrically activated only when the filtered input light pulse is about to impact it.Time-multiplexing the input signal through multiple optical filters and time-sequencing the optical detector enables the device to detect and analyze 2-3 orders of magnitude faster than current designs. In one embodiment, the system may be employed for the diagnostics of a pathological condition of skin tissue in patients, such as malignant melanoma or other types of skin cancers and abnormal conditions.

    Abstract translation: 实现时间分辨拉曼光谱仪的新架构比现有系统快2-3个数量级。 在一个实施例中,本发明采用旋转光开关,通过多个带通滤波器对输入信号进行时间复用,并将其转换成仅在滤波后的输入光脉冲即将影响时才被电激活的单个光检测器。 通过多个光学滤波器对输入信号进行时分复用,并对光学检测器进行时间排序,使器件能够比目前的设计更快地检测和分析2-3个数量级。 在一个实施方案中,该系统可用于诊断患者皮肤组织的病理状况,例如恶性黑素瘤或其他类型的皮肤癌症和异常状况。

    Spectral instrument
    47.
    发明授权
    Spectral instrument 失效
    光谱仪

    公开(公告)号:US07466419B2

    公开(公告)日:2008-12-16

    申请号:US10547128

    申请日:2004-02-26

    Abstract: In this spectral instrument, a plurality of interference filters 31, 32 . . . with transmitting wavebands different from each other are arranged in order so that light reflected by a specific interference filter 31 is made incident on the interference filter 32 on the next stage, and at positions on which light transmitted through each interference filter is made incident, photodetecting devices 41, 42 . . . are provided, wherein a silver thin film 31a with a thickness of 20 to 200 nm is provided on the light incidence surface side of the interference filter 31 on the first stage.

    Abstract translation: 在该光谱仪器中,多个干涉滤光器31,32。 。 。 相互不同的发送波段按顺序排列,使得由特定干涉滤光器31反射的光入射到下一级的干涉滤光器32上,并且在透过每个干涉滤光器的光入射的位置处受光检测 装置41,42。 。 。 ,其中在第一级上的干涉滤光器31的光入射面侧设置有厚度为20〜200nm的银薄膜31a。

    OPTICAL MEASUREMENT APPARATUS
    48.
    发明申请
    OPTICAL MEASUREMENT APPARATUS 审中-公开
    光学测量装置

    公开(公告)号:US20080117421A1

    公开(公告)日:2008-05-22

    申请号:US12014429

    申请日:2008-01-15

    Abstract: An optical measurement apparatus which includes at least one each of a light source, an optical element, a photodetector, and a sample container, and which measures a physical property of a biological sample in a solution retained by the sample container according to a plurality of kinds of measurement items, wherein a combination of the light source, the optical element, and the photodetector is selected or changed according to the measurement item, and a position where the photodetector is located is adjusted according to the selection or change based on intensity of light accepted by the photodetector.

    Abstract translation: 一种光学测量装置,其包括光源,光学元件,光电检测器和样品容器中的至少一个,并且根据多个测量装置测量由样品容器保留的溶液中的生物样品的物理性质 根据测量项目选择或改变光源,光学元件和光电检测器的组合的测量项目的种类,并且根据根据测量项目的强度来选择或改变光电探测器所在的位置 由光电检测器接受的光。

    REFRACTIVE-DIFFRACTIVE SPECTROMETER
    49.
    发明申请
    REFRACTIVE-DIFFRACTIVE SPECTROMETER 失效
    折射衍射光谱仪

    公开(公告)号:US20030231308A1

    公开(公告)日:2003-12-18

    申请号:US09991038

    申请日:2001-11-21

    Abstract: A diffraction grating and a prism with the appropriate characteristics are employed to provide a combined dispersive characteristic that is substantially linear over the visible spectrum. Radiation from the grating and prism is collimated by a lens towards a detector array. The grating or a telecentric stop between the grating and prism is placed at a focal point of the lens in a telecentric arrangement so that equal magnification is achieved at the detector array. If the detector array is replaced by a plurality of optical channels, a multiplexer/demultiplexer is obtained.

    Abstract translation: 使用衍射光栅和具有适当特性的棱镜来提供在可见光谱上基本上线性的组合色散特性。 来自光栅和棱镜的辐射由透镜朝向检测器阵列准直。 光栅或光栅和棱镜之间的远心光阑以远心布置放置在透镜的焦点处,使得在检测器阵列处实现相等的放大倍率。 如果检测器阵列被多个光通道替代,则获得多路复用器/解复用器。

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