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    Device for evaluating biochemical samples
    42.
    发明授权
    Device for evaluating biochemical samples 有权
    用于评估生物化学样品的装置

    公开(公告)号：US08454894B2

    公开(公告)日：2013-06-04

    申请号：US11662321

    申请日：2005-08-24

    Applicant: Franz Padinger ,  Klaus G. Schröter

    Inventor： Franz Padinger ,  Klaus G. Schröter

    IPC: G01N27/00

    CPC classification number: G01N21/78 ,  G01N21/75 ,  G01N2201/0628 ,  H01L27/146

    Abstract: Described is a device for evaluating biochemical samples (1), with a sample carrier (2), with an image recording means having a light-sensitive layer (3) connected to an evaluation circuit (10), and with a means for illuminating the samples (1). In order to provide simple design conditions, it is proposed that the light-sensitive layer (3), provided on the sample carrier (2), of the image recording means comprise a photoactive layer (4) based on organic semiconductors between two electrode layers (5, 6), of which the electrode layer (6) between the photoactive layer (4) and the samples (1) is translucent at least in certain regions.

    Abstract translation: 描述了一种用于用样品载体（2）评价生物化学样品（1）的装置，具有连接到评估电路（10）的具有感光层（3）的图像记录装置，以及用于照亮 样品（1）。 为了提供简单的设计条件，提出了设置在图像记录装置的样品载体（2）上的感光层（3）包括基于两个电极层之间的有机半导体的光活性层（4） （5,6），其中光活性层（4）和样品（1）之间的电极层（6）至少在某些区域是半透明的。

    BIOSENSOR AND A RELATED MANUFACTURING METHOD
    44.
    发明申请
    BIOSENSOR AND A RELATED MANUFACTURING METHOD 审中-公开
    生物传感器和相关制造方法

    公开(公告)号：US20110008210A1

    公开(公告)日：2011-01-13

    申请号：US12918843

    申请日：2009-02-23

    Applicant: Marika Kurkinen ,  Jukka Hast ,  Markus Tuomikoski ,  Markku Kansakoski ,  Harri Kopola

    Inventor： Marika Kurkinen ,  Jukka Hast ,  Markus Tuomikoski ,  Markku Kansakoski ,  Harri Kopola

    IPC: G01N21/76 ,  H01J9/227

    CPC classification number: G01N21/648 ,  G01N2021/056 ,  G01N2201/0628

    Abstract: A biosensor platform for a biosensor adapted to detect one or more predetermined target analytes in a sample, includes a waveguide for transporting light emitted by a light source, at least one light source including an OLED, for incoupling light to the waveguide, the light source being arranged on the waveguide, a binding site including immobilized biorecognition material capable of binding to the target analytes, the binding site positioned relative to the waveguide such that evanescent field triggered by the light propagating in the waveguide extend to the binding site, a microfluidic layer including one or more microfluidic cavities for conveying the sample past the binding site to enable at least part of the target analytes of the sample to bind to the immobilized biorecognition material. The biosensor platform is configured to enable, when least part of the target analytes are bound to the immobilized biorecognition material, fluorescent markers associated with the bound target or other analytes to be excited by the evanescent field so as to emit fluorescence detectable by a detector.

    Abstract translation: 一种用于检测样品中的一种或多种预定目标分析物的生物传感器的生物传感器平台，包括用于传输由光源发射的光的波导，至少一个包括OLED的光源，用于将光耦合到波导，光源 布置在波导上的结合位点，包括能够结合靶分析物的固定化生物识别材料的结合位点，相对于波导定位的结合位点使得由在波导中传播的光触发的消逝场延伸到结合位点，微流体层 包括用于将样品传送通过结合位点的一个或多个微流体腔，以使至少部分样品的目标分析物与固定的生物识别材料结合。 生物传感器平台被配置为使得当目标分析物的至少一部分与固定的生物识别材料结合时，与结合的靶标相关联的荧光标记或其它分析物将被ev逝场激发，以便发射由检测器检测到的荧光。

    Device for Evaluating Biochemical Samples
    46.
    发明申请
    Device for Evaluating Biochemical Samples 有权
    评估生物化学样品的装置

    公开(公告)号：US20070292307A1

    公开(公告)日：2007-12-20

    申请号：US11662321

    申请日：2005-08-24

    Applicant: Franz Padinger ,  Klaus Klaus

    Inventor： Franz Padinger ,  Klaus Klaus

    IPC: B01J19/00

    CPC classification number: G01N21/78 ,  G01N21/75 ,  G01N2201/0628 ,  H01L27/146

    Abstract: Described is a device for evaluating biochemical samples (1), with a sample carrier (2), with an image recording means having a light-sensitive layer (3) connected to an evaluation circuit (10), and with a means for illuminating the samples (1). In order to provide simple design conditions, it is proposed that the light-sensitive layer (3), provided on the sample carrier (2), of the image recording means comprise a photoactive layer (4) based on organic semiconductors between two electrode layers (5, 6), of which the electrode layer (6) between the photoactive layer (4) and the samples (1) is translucent at least in certain regions.

    Abstract translation: 描述了一种用于用样品载体（2）评价生物化学样品（1）的装置，具有连接到评估电路（10）的具有感光层（3）的图像记录装置，以及用于照亮 样品（1）。 为了提供简单的设计条件，提出了设置在图像记录装置的样品载体（2）上的感光层（3）包括基于两个电极层之间的有机半导体的光活性层（4） （5,6），其中光活性层（4）和样品（1）之间的电极层（6）至少在某些区域是半透明的。

    Novel device, system and method for fluorescence detection
    47.
    发明申请
    Novel device, system and method for fluorescence detection 审中-公开
    用于荧光检测的新型装置，系统和方法

    公开(公告)号：US20050109951A1

    公开(公告)日：2005-05-26

    申请号：US10500186

    申请日：2002-12-26

    Applicant: Falk Fish ,  Zvi Greenberg ,  Ouriel Faktor

    Inventor： Falk Fish ,  Zvi Greenberg ,  Ouriel Faktor

    IPC: G01N21/64 ,  G01N21/75 ,  G01N21/77 ,  G01N21/86

    CPC classification number: G01N21/645 ,  G01N21/64 ,  G01N21/8483 ,  G01N33/549 ,  G01N2021/6439 ,  G01N2021/757 ,  G01N2021/7759 ,  G01N2021/7763 ,  G01N2021/7786 ,  G01N2201/0221 ,  G01N2201/0222 ,  G01N2201/0245 ,  G01N2201/062 ,  G01N2201/0628

    Abstract: A device, system and method for portable fluorescence detection. The portable device of the present invention features a low power light, in which a wavelength range is defined as at least one wavelength of light. The light source is preferably highly energy efficient, such that a majority of the electrical power which is consumed is then converted into transmitted light. The emitted light from the excited fluorophore is then preferably detected with any low cost and low power photodetector. Although optionally a highly sensitive optical detector may be used, preferably fluorescence is detected with any light sensing device, such as a regular photodiode or a CCD (charge-coupled device) sensor for example.

    Abstract translation: 用于便携式荧光检测的装置，系统和方法。 本发明的便携式装置具有低功率光，其中波长范围被定义为至少一个波长的光。 光源优选地是高能量的，使得消耗的大部分电功率然后被转换成透射光。 然后优选用任何低成本和低功率光电检测器检测来自激发的荧光团的发射光。 尽管可选地使用高灵敏度的光学检测器，但是优选地，例如使用诸如常规光电二极管或CCD（电荷耦合器件）传感器的任何光感测装置来检测荧光。

    Optical instrument including excitation source
    48.
    发明申请
    Optical instrument including excitation source 有权
    光学仪器包括激发源

    公开(公告)号：US20040038390A1

    公开(公告)日：2004-02-26

    申请号：US10440719

    申请日：2003-05-19

    Inventor： Steven J. Boege ,  Mark F. Oldham ,  Eugene F. Young

    IPC: C12M001/34

    CPC classification number: G01N21/6452 ,  B01L7/52 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2021/6463 ,  G01N2021/6482 ,  G01N2201/0628 ,  G01N2201/0635 ,  Y10S435/808

    Abstract: An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with an excitation beam generated by a light source. A collimating lens can be disposed along a beam path between the light source and the reaction regions to form bundles of collimated excitation beams, wherein each bundle corresponds to a respective reaction region. Methods of analysis using the optical instrument are also provided.

    Abstract translation: 提供了一种光学仪器，用于同时用由光源产生的激发光束照射两个或更多间隔开的反应区域。 准直透镜可以沿着光源和反应区域之间的光束路径设置，以形成准直激励束的束，其中每个束对应于相应的反应区域。 还提供了使用光学仪器的分析方法。

    기판 조명 및 검사 시스템
    50.
    发明公开
    기판 조명 및 검사 시스템 无效
    基板照明和检查系统

    公开(公告)号：KR1020090008432A

    公开(公告)日：2009-01-21

    申请号：KR1020087029346

    申请日：2007-03-15

    Applicant: 에크리텍 유에스에이 인크

    Inventor： 로빈스,마이클디. ,  포더하세,폴에프. ,  베일리,조엘비. ,  응우옌,케빈

    IPC: G01N31/00

    CPC classification number: G01N21/9503 ,  G01N21/4738 ,  G01N2201/0621 ,  G01N2201/0628

    Abstract: A substrate illumination and inspection system provides for illuminating and inspecting a substrate particularly the substrate edge. The system uses a light diffuser with a plurality of lights disposed at its exterior or interior for providing uniform diffuse illumination of a substrate. An optic and imaging system exterior of the light diffuser are used to inspect the plurality of surfaces of the substrate including specular surfaces. The optic is held at an angle from a surface normal to avoid reflective artifacts from the specular surface of the substrate. The optic can be rotated radially relative to a center point of the substrate edge to allow for focused inspection of all surfaces of the substrate edge. The plurality of lights can modulate color and intensity of light to enhance inspection of the substrate for defects.

    Abstract translation: 衬底照明和检查系统提供用于照明和检查衬底，特别是衬底边缘。 该系统使用具有设置在其外部或内部的多个光的光漫射器，用于提供衬底的均匀漫射照明。 光扩散器的光学和成像系统外部用于检查包括镜面的基板的多个表面。 光学元件保持与表面法线成一定角度，以避免来自基板的镜面的反射伪影。 光学元件可以相对于基板边缘的中心点径向旋转，以允许对基板边缘的所有表面进行聚焦检查。 多个光可以调制光的颜色和强度，以增强基板对缺陷的检查。

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