公开(公告)号：US20040233426A1

公开(公告)日：2004-11-25

申请号：US10807265

申请日：2004-03-24

Applicant: RIKEN and MACHIDA ENDOSCOPE CO., LTD.

Inventor： Yuichi Komachi ,  Hideo Tashiro ,  Katsuo Aizawa

IPC: G01J003/44

CPC classification number: G02B6/032 ,  G01J3/44 ,  G02B6/0096

Abstract: A Raman probe that does not produce Raman scattering that interferes with measurement, and a Raman spectrum measuring apparatus utilizing the Raman probe. The Raman probe comprises a hollow wave-guide path 10 with a light-transmitting medium (core) that is evacuated or filled with a gas that does not produce Raman scattering, such as air.

Abstract translation: 不产生干涉测量的拉曼散射的拉曼探头和利用拉曼探针的拉曼光谱测量装置。 拉曼探头包括具有被抽空或填充有不产生拉曼散射的气体（例如空气）的透光介质（芯）的中空波导路径10。

公开(公告)号：US20040233425A1

公开(公告)日：2004-11-25

申请号：US10492442

申请日：2004-04-13

Inventor： Robert L. Long ,  David G. Marrow

IPC: G01J003/44

CPC classification number: B01J8/1809 ,  B01J19/0006 ,  B01J2208/00964 ,  C08F10/00 ,  C08F210/16 ,  C08F2400/02 ,  G01N21/65 ,  C08F2/00 ,  C08F2/34 ,  C08F210/08 ,  C08F2500/12 ,  C08F210/14

Abstract: Methods are provided for determining and controlling polymer properties on-line in a polymerization reactor system, such as a fluidized bed reactor. The methods include obtaining a regression model for determining a polymer property, the regression model including principal component loadings and principal component scores, acquiring a Raman spectrum of a polyolefin sample comprising polyolefin, calculating a new principal component score from at least a portion of the Raman spectrum and the principal component loadings, and calculating the polymer property by applying the new principal component score to the regression model. The property can be controlled by adjusting at least one polymerization parameter based on the calculated polymer property.

Abstract translation: 提供了用于在聚合反应器系统如流化床反应器中在线确定和控制聚合物性质的方法。 所述方法包括获得用于确定聚合物性质的回归模型，包括主成分负荷和主成分分数的回归模型，获得包含聚烯烃的聚烯烃样品的拉曼光谱，从至少一部分拉曼计算新的主成分分数 光谱和主成分负荷，并通过将新的主成分分数应用于回归模型来计算聚合物性质。 可以通过基于所计算的聚合物性质调节至少一个聚合参数来控制该性质。

公开(公告)号：US20040057047A1

公开(公告)日：2004-03-25

申请号：US10663491

申请日：2003-09-15

Applicant: Leica Microsystems Heidelberg GmbH

Inventor： Werner Knebel

IPC: G01J003/44 ,  G01N021/65

CPC classification number: G02B21/002 ,  G01J3/44 ,  G01N2021/653

Abstract: A microscope for CARS microscopy has means for generating a pump light beam and a Stokes light beam that can be directed coaxially through a microscope optical system onto a sample. A detector detects the detection light proceeding from the sample. The means for generating the pump light beam and the Stokes light beam contain a laser and encompass a microstructured optical element that spectrally broadens the light of the laser.

Abstract translation: 用于CARS显微镜的显微镜具有用于产生泵浦光束和可以通过显微镜光学系统同轴地引导到样品上的斯托克斯光束的装置。 检测器检测从样品进行的检测光。 用于产生泵浦光束和斯托克斯光束的装置包含激光并且包围光谱拓宽激光的光的微结构化光学元件。

公开(公告)号：US20040051867A1

公开(公告)日：2004-03-18

申请号：US10428398

申请日：2003-05-02

Applicant: INTERNATIONAL TECHNOLOGIES (LASERS) LTD.

Inventor： Mordechai Brestel ,  Michael Gaft ,  Uzi Sharon

IPC: G01J003/44 ,  G01J003/30

CPC classification number: G01N21/6456 ,  G01J3/2889 ,  G01J3/44 ,  G01J3/4406 ,  G01N21/6408 ,  G01N21/65 ,  G01N21/658

Abstract: A system for detecting controlled substances on an object including at least one laser for illuminating at least part of an object with laser energy and either a second harmonic detector or a luminescence controlled substance detector, or both. Additionally, a system also including a Raman scattering controlled substance detector is disclosed.

Abstract translation: 一种用于检测物体上的受控物质的系统，包括用于用激光能量照射至少一部分物体的至少一个激光器，以及二次谐波检测器或发光受控物质检测器或两者。 另外，还公开了一种还包括拉曼散射控制物质检测器的系统。

公开(公告)号：US20040046121A1

公开(公告)日：2004-03-11

申请号：US10346837

申请日：2003-01-16

Inventor： Josh H. Golden ,  Hugh E. Gotts ,  Jay Jung ,  Marc Van den Berg

IPC: G01J003/44

CPC classification number: G01N21/65 ,  G01J3/44 ,  G01N21/05 ,  G01N2021/0346 ,  G01N2021/651 ,  G01N2021/656 ,  G01N2021/8528

Abstract: The present invention relates generally to the field of electrolytic and electroless metal plating. A method and system for determining the presence of analytes in metal plating solutions using Raman spectroscopy is described. High absorbance plating bath samples are analyzed by Raman spectroscopy by minimizing the penetration depth of the incident light beam. A chemical auto-dosing system for controlling the concentration of one or more plating bath additives in a metal plating bath is also provided.

Abstract translation: 本发明一般涉及电解和无电镀金属领域。 描述了使用拉曼光谱测定金属电镀溶液中分析物的存在的方法和系统。 通过使入射光束的穿透深度最小化，通过拉曼光谱分析高吸光度电镀浴样品。 还提供了用于控制金属电镀浴中的一种或多种电镀浴添加剂的浓度的化学自动计量系统。

公开(公告)号：US20040021860A1

公开(公告)日：2004-02-05

申请号：US10339807

申请日：2003-01-10

Inventor： Charles W. Gardner, JR. ,  John S. Maier ,  Matthew P. Nelson ,  Robert C. Schweitzer ,  Patrick J. Treado ,  G. Steven Vanni ,  Juliane Wolfe

IPC: G01J003/44

CPC classification number: G01N21/6486 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/2823 ,  G01J3/44 ,  G01N21/31 ,  G01N21/33 ,  G01N21/359 ,  G01N21/645 ,  G01N21/6456 ,  G01N21/6458 ,  G01N21/65 ,  G01N2021/1736 ,  G01N2021/6421 ,  G01N2021/6423 ,  G01N2021/656

Abstract: Pathogenic microorganisms are detected and classified by spectral imaging of the Raman light scattered by the organisms.

Abstract translation: 通过生物体散射的拉曼光的光谱成像检测和分类病原微生物。

公开(公告)号：US20040012778A1

公开(公告)日：2004-01-22

申请号：US10196649

申请日：2002-07-16

Inventor： Yong-Qing Li ,  Mumtaz A. Dinno

IPC: G01J003/44

CPC classification number: G01N21/658 ,  G01J3/44

Abstract: Methods and systems for studying microscopic particles are provided. An optical trap for a selected microscopic particle can be formed with a laser beam at a first power level. The laser beam can have a variable power level associated therewith. The variable power level can be increased to a second power level. The laser beam at the second power level can produce Raman scattering signals. The second power level can provide sufficient excitation energy to the selected microscopic particle to produce Raman scattering signals and the second power level is higher than the first power level. A Raman spectrum can be detected from the Raman scattering signals produced by the laser beam at the second power level.

Abstract translation: 提供了研究微观粒子的方法和系统。 可以用第一功率水平的激光束形成所选择的微观粒子的光阱。 激光束可以具有与其相关联的可变功率电平。 可变功率电平可以增加到第二功率电平。 第二功率电平的激光束可产生拉曼散射信号。 第二功率电平可以为选定的微观粒子提供足够的激发能量以产生拉曼散射信号，并且第二功率电平高于第一功率电平。 拉曼光谱可以从激光束在第二功率电平产生的拉曼散射信号中检测出来。

公开(公告)号：US20040004715A1

公开(公告)日：2004-01-08

申请号：US10610481

申请日：2003-06-30

Inventor： David Tuschel ,  Patrick J. Treado ,  Joseph E. Demuth

IPC: G01J003/44

CPC classification number: G02B21/365 ,  C08K9/02 ,  C08K2201/014 ,  G01B11/2545 ,  G01J3/2823 ,  G01J3/44 ,  G01J3/447 ,  G01N21/3563 ,  G01N21/65 ,  G02B6/32 ,  G02B21/00 ,  G02B21/06 ,  G06K9/00013 ,  G06T5/50

Abstract: An ion implanted semiconductor surface is illuminated with a flood illumination of monochromatic radiation, and an image of the surface is taken using light which has been Raman scattered. The illumination and imaging system are calibrated by flood illuminating a uniformly Raman scattering surface.

Abstract translation: 用单色辐射的泛光照射照射离子注入的半导体表面，并且使用已经被拉曼散射的光进行表面的图像。 照明和成像系统通过泛光照射均匀的拉曼散射表面来校准。

公开(公告)号：US20040004714A1

公开(公告)日：2004-01-08

申请号：US10368176

申请日：2003-02-18

Inventor： Harry Owen ,  Mark Welch ,  Michael J. Pelletier

IPC: G01J003/44

CPC classification number: G01J3/44 ,  G01N21/65

Abstract: A method of monitoring sample crystallization from a solution. The method includes the collection of multiple Raman spectra from a sample dissolved in a solvent as a function of time and under conditions promoting crystallization. Within each of the multiple Raman spectra, a first signal is identified corresponding to the sample associated with the solvent. A second signal corresponding to the sample in a microcrystallite state is also identified. Thereafter, the intensity of the multiple Raman spectra are measured for an increase relating to formation of the sample in a microcrystallite state. A method of monitoring sample crystallization from a solution as a function of turbidity is also disclosed. The method includes the collection of multiple Raman spectra from a sample dissolved in a solvent as a function of time under conditions promoting crystallization. A decrease in intensity is measured across the multiple Raman spectrum over time, the intensity decrease associated with macroscopic crystallization opacity. The decrease in intensity is finely correlated with the onset of macroscopic crystallization of the sample from the solvent.

Abstract translation: 从溶液中监测样品结晶的方法。 该方法包括从溶解在溶剂中的样品中收集多个拉曼光谱作为时间和促进结晶的条件的函数。 在多个拉曼光谱的每一个内，识别出与溶剂相关的样品对应的第一信号。 还鉴定了与微晶状态的样品相对应的第二信号。 此后，测量多拉曼光谱的强度与微细晶体状态下样品形成有关的增加。 还公开了一种监测来自溶液的样品结晶作为浊度的函数的方法。 该方法包括在促进结晶的条件下，从溶解在溶剂中的样品中收集多个拉曼光谱作为时间的函数。 随着时间的推移，多个拉曼光谱测量强度的降低，与宏观结晶不透明度相关的强度降低。 强度的降低与来自溶剂的样品的宏观结晶的发生很相关。

公开(公告)号：US20030218744A1

公开(公告)日：2003-11-27

申请号：US09955712

申请日：2001-09-19

Inventor： Vladimir M. Shalaev ,  Z. Charles Ying ,  Andrey K. Sarychev

IPC: G01J003/44

CPC classification number: G01N21/658 ,  B82Y10/00 ,  G01N2021/655

Abstract: An optical sensing enhancing material comprising a medium, the medium comprising a semicontinuous metal film of randomly distributed metal particles and their clusters at approximately their percolation threshold. The medium preferably additionally comprises a microcavity/microresonator. Also devices and methods employing such material.

Abstract translation: 一种包括介质的光学感测增强材料，所述介质包括大致其渗透阈值下随机分布的金属颗粒及其簇的半连续金属膜。 该介质优选地另外包括微腔/微谐振器。 也是采用这种材料的装置和方法。