公开(公告)号：EP1343868A1

公开(公告)日：2003-09-17

申请号：EP02731300.6

申请日：2002-04-08

Applicant: Dade MicroScan Inc.

Inventor： DUNFEE, William, David ,  GEMMELL, Bruce, McLean ,  KAMINSKI, Edward, Stephen ,  MAZZA, John, Charles ,  FARINA, Edward, Francis ,  KRUFKA, Frank, Stephen

IPC: C12M1/34 ,  C12Q1/18 ,  G01N21/00 ,  G01N21/03 ,  G01N35/00 ,  G01N35/02

CPC classification number: G01N21/253 ,  G01N35/00029 ,  G01N35/025 ,  G01N2035/00049 ,  G01N2035/00148

Abstract: Performing antibiotic testing on samples contained in test arrays by orienting the arrays relative to the direction of gravity so that test solution within the microwells is drawn downwards and air within the microwells is forced to the uppermost portion of the test array. Antibiotic testing is conducted using an interrogating beam of radiation passing horizontally through the microwells at locations devoid of air bubbles.

公开(公告)号：EP1342069A1

公开(公告)日：2003-09-10

申请号：EP02761242.3

申请日：2002-07-30

Applicant: Dade MicroScan Inc.

Inventor： GEBRIAN, Peter, Louis ,  CAMERON, Allan, Lee ,  MUDD, Alan, Cristopher ,  O'BRIEN, Richard ,  SWEET, David, Orrin ,  WEST, Adrian, Mark, Thomas

IPC: G01N21/00

CPC classification number: B01F13/0059 ,  B01F13/0818 ,  B01L3/5027 ,  B01L9/00 ,  B01L2300/0864 ,  B01L2300/10 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/049 ,  G01N35/00029 ,  G01N35/00069 ,  G01N2035/00089 ,  G01N2035/00148

Abstract: A closed elongate canister (32) having a generally rectangular cross-section formed by a front wall (290), a five-section back wall (291) and two side walls (292), the walls of dimensions to house a plurality of ID test rotors stacked one atop another within the canister (32).

公开(公告)号：EP1325306A1

公开(公告)日：2003-07-09

申请号：EP02764179.4

申请日：2002-04-08

Applicant: Dade MicroScan Inc.

Inventor： FARINA, Edward, Francis ,  GEMMELL, Bruce, McLean ,  MAZZA, John, Charles ,  MCVEY, Michael, Taylor ,  KAMINSKI, Edward, Stephen ,  HADDAD, Antoine, Elias ,  GEBRIAN, Peter, Louis

IPC: G01N21/00 ,  G01N9/30 ,  C12M1/34 ,  C12M3/00

CPC classification number: B01L3/5085 ,  B01L7/00 ,  C12M41/36 ,  C12M41/48 ,  G01N35/025 ,  G01N2035/00148 ,  G01N2035/1076

Abstract: A circular shaped rotor (16) to facilitate automated identification testing of microorganisms in a microbiology analyzer (10) having two circular arrays (120,124) of microwells downwardly projecting from the top of the rotor (16) connected to a recessed central region (114) by a plurality of microchannels (118,122) formed in the upper surface and connecting the recessed central portion to the second plurality of microwells; the rotor is further adapted to be rotated by a source of rotational energy and moved throughout the analyzer using troughs (126) formed near its outer diameter.

Abstract translation: 一种圆形转子（16），用于促进微生物学分析仪（10）中微生物的自动识别测试，微生物分析仪具有两个从连接到凹入的中央区域（114）的转子（16）的顶部向下突出的微孔圆形阵列（120,124） 通过形成在所述上表面中并且将所述凹入中央部分连接到所述第二多个微孔的多个微通道（118,122） 转子还适于通过旋转能量源旋转，并且使用在其外径附近形成的槽（126）移动穿过分析仪。

公开(公告)号：EP1335969A1

公开(公告)日：2003-08-20

申请号：EP02731299.0

申请日：2002-04-08

Applicant: Dade MicroScan Inc.

Inventor： FARINA, Edward, Francis ,  KAMINSKI, Edward, Stephen ,  MAZZA, John, Charles ,  GEMMELL, Bruce, McLean ,  DUNFEE, William, David

IPC: C12M1/22 ,  C12M1/34 ,  C12Q1/02 ,  C12Q1/18 ,  C12Q1/24 ,  G01N21/00

CPC classification number: C12Q1/18

Abstract: A microbiological test array with a plurality of microwells connected by a microchannel to a solution reservoir. Subsequent to filling the microwells, the microchannels are sealed to protect the integrity of the solution in the test microwells.

公开(公告)号：EP1177448A2

公开(公告)日：2002-02-06

申请号：EP00930540.0

申请日：2000-05-01

Applicant: Dade MicroScan Inc.

Inventor： WILLIAM, Gregory, B. ,  NOTHAFT, Daniel ,  ENSCOE, Glenn, F. ,  BURTNER, Kathleen, N. ,  KANGAS, Monte

IPC: G01N35/02 ,  C12M1/34 ,  C12M1/20

CPC classification number: G01N35/028 ,  G01N35/0092 ,  G01N2035/0093 ,  G01N2035/0097

Abstract: In response to the need for highly-sensitive antibiotic susceptibility assays and identification assays that do not require extensive incubation times, the present invention provides automated assay methods and systems that permit the determination of antibiotic susceptibilities and/or microorganism identification in a timeframe that is substantially shorter than has previously been attainable using a hybrid system that combines turbimetric and fluorescence determinations using a single, clear-plastic assay platform. Related devices, kits, and components thereof are also disclosed.

公开(公告)号：EP0609431B1

公开(公告)日：1997-10-08

申请号：EP93920297.4

申请日：1993-08-24

Applicant: Dade MicroScan Inc.

Inventor： COAKLEY, Joseph ,  GODSEY, James ,  SHERMAN, David

IPC: G01N35/00 ,  B01L3/00

CPC classification number: G01N35/1097 ,  B01L3/502 ,  B01L2400/0644 ,  Y10T436/25

Abstract: A sealable container for holding an analytical sample for processing is disclosed. The container includes a body (12) with a dispensing port (26) and an insert member (14) slidably received in the body (12). The insert member and the body are movable relative to each other between a first position, in which the outlet port (18) is substantially aligned with the dispensing port (26), and a second position, in which the outlet port is substantially out of alignment with the dispensing port. Sealing means (48), which may take the form of O-rings between the insert member and the body, provide a substantially airtight, hermetic seal between a reaction chamber formed in the insert member and the body so that the reaction chamber can be sealed or isolated from the outside environment. The container is particularly adapted to contain the processes of nucleic acid amplification and to thereby reduce the problems of sample crosscontamination encountered in such processes. A method of processing an analytical sample using such a container is also disclosed.

公开(公告)号：EP0925369A1

公开(公告)日：1999-06-30

申请号：EP98910425.0

申请日：1998-03-16

Applicant: Dade Microscan Inc.

Inventor： GODSEY, James, H. ,  NOTHAFT, Daniel, M.

IPC: C12Q1

CPC classification number: C12Q1/04 ,  Y10S435/843 ,  Y10S435/851 ,  Y10S435/853 ,  Y10S435/871 ,  Y10S435/882 ,  Y10S435/885 ,  Y10S435/968

Abstract: The present invention relates to universal test systems and methods of use thereof for identifying a microorganism among at least two groups of widely divergent microorganisms. The universal test system comprises a predetermined combination of non-redundant biochemical tests comprising a substrate for at least one enzyme wherein the substrate, if acted on by the enzyme results in formation of a detectable product. Detectable products from the combination of biochemical tests are then used to identify the microorganism.

公开(公告)号：EP0565696B1

公开(公告)日：1996-09-11

申请号：EP92923233.8

申请日：1992-10-27

Applicant: Dade MicroScan Inc.

Inventor： GRINER, Christopher, D. ,  MALONE, Brian, G.

IPC: B01L9/00 ,  G01N35/00 ,  A47B88/00

CPC classification number: G01N35/04 ,  B01L3/50853 ,  B01L9/523 ,  B01L2300/0829 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/0425 ,  G01N2035/0475

Abstract: A holder (14) for storing a specimen tray (12) with a removable cover member (86) includes a frame with oppositely facing first (60) and second (58) access openings. The first access (60) opening receives the specimen tray (12) and cover member (86). The holder (14) supports the specimen tray (12) and cover member (86) within the storage area between a pair of oppositely spaced tray support ledges (212). The second access opening (58) receives an external member (24) that moves vertically in the storage area to lift the specimen tray (12) from the tray support ledges (212) and that moves horizontally out of the storage area to move the lifted specimen tray (12) from the storage area through the second access opening. The holder (218) pivots the cover member (86) away from the specimen tray (12) to retain the cover member (86) in a tilted orientation within the storage area free of the removed specimen tray until its return.

公开(公告)号：EP0565700B1

公开(公告)日：1996-08-21

申请号：EP92923464.9

申请日：1992-10-27

Applicant: Dade MicroScan Inc.

Inventor： GARAND, Steven, A. ,  DANIEL, Carl, P.

IPC: H02P8/00

CPC classification number: G01N35/1002 ,  G01N35/025 ,  G01N35/028 ,  G01N2021/1759 ,  G01N2035/00079 ,  G01N2035/00455 ,  G01N2035/042 ,  G01N2035/0425 ,  G01N2035/0463 ,  G01N2035/0475 ,  G01N2201/0407 ,  G01N2201/0446 ,  G01N2201/08 ,  G01N2201/1283

Abstract: An improved control system for a stepper motor coil (190) includes a flyback circuit (192) that dissipates coil energy slowly while the coil is energized and operated in the chopping mode, while dissipating coil energy rapidly when the coil is switched to its de-energized phase.