公开(公告)号：WO2002086054A1

公开(公告)日：2002-10-31

申请号：PCT/US2002/011080

申请日：2002-04-08

Applicant: DADE MICROSCAN INC.

Inventor： FARINA, Edward, Francis ,  KAMINSKI, Edward, Stephen ,  MAZZA, John, Charles ,  GEMMELL, Bruce, McLean ,  DUNFEE, William, David

IPC: C12M1/22

CPC classification number: C12Q1/18

Abstract: A microbiological test array with a plurality of microwells connected by a microchannel to a solution reservoir. Subsequent to filling the microwells, the microchannels are sealed to protect the integrity of the solution in the test microwells.

Abstract translation: 具有多个微孔的微生物测试阵列，其通过微通道连接到溶液储存器。 在填充微孔之后，密封微通道以保护测试微孔中溶液的完整性。

公开(公告)号：WO2002086055A1

公开(公告)日：2002-10-31

申请号：PCT/US2002/011083

申请日：2002-04-08

Applicant: DADE MICROSCAN INC.

Inventor： DUNFEE, William, David ,  GEMMELL, Bruce, McLean ,  KAMINSKI, Edward, Stephen ,  MAZZA, John, Charles ,  FARINA, Edward, Francis ,  KRUFKA, Frank, Stephen

IPC: C12M1/34

CPC classification number: G01N21/253 ,  G01N35/00029 ,  G01N35/025 ,  G01N2035/00049 ,  G01N2035/00148

Abstract: Performing antibiotic testing on samples contained in test arrays by orienting the arrays relative to the direction of gravity so that test solution within the microwells is drawn downwards and air within the microwells is forced to the uppermost portion of the test array. Antibiotic testing is conducted using an interrogating beam of radiation passing horizontally through the microwells at locations devoid of air bubbles.

Abstract translation: 通过相对于重力方向定向阵列，使测试阵列中包含的样品进行抗生素测试，使得微孔内的测试溶液向下拉，微孔内的空气被迫到测试阵列的最上部。 使用询问的辐射束在没有气泡的位置水平穿过微孔进行抗生素测试。

公开(公告)号：WO2002086465A1

公开(公告)日：2002-10-31

申请号：PCT/US2002/011084

申请日：2002-04-08

Applicant: DADE MICROSCAN INC.

Inventor： FARINA, Edward, Francis ,  GEMMELL, Bruce, McLean ,  MAZZA, John, Charles ,  MCVEY, Michael, Taylor ,  KAMINSKI, Edward, Stephen ,  HADDAD, Antoine, Elias ,  GEBRIAN, Peter, Louis

IPC: G01N21/00

CPC classification number: B01L3/5085 ,  B01L7/00 ,  C12M41/36 ,  C12M41/48 ,  G01N35/025 ,  G01N2035/00148 ,  G01N2035/1076

Abstract: A circular shaped rotor (16) to facilitate automated identification testing of microorganisms in a microbiology analyzer (10) having two circular arrays (120,124) of microwells downwardly projecting from the top of the rotor (16) connected to a recessed central region (114) by a plurality of microchannels (118,122) formed in the upper surface and connecting the recessed central portion to the second plurality of microwells; the rotor is further adapted to be rotated by a source of rotational energy and moved throughout the analyzer using troughs (126) formed near its outer diameter.

Abstract translation: 一种圆形转子（16），用于在微生物学分析仪（10）中有助于微生物分析仪（10）的自动识别测试，所述微生物学分析仪具有从连接到凹入的中心区域（114）的转子（16）的顶部向下突出的微孔的两个圆形阵列（120,124） 通过形成在上表面中的多个微通道（118,122）并将凹入的中心部分连接到第二多个微孔; 转子还适于通过旋转能量源旋转并且通过在其外径附近形成的槽（126）移动到整个分析器中。

公开(公告)号：WO2002068581A1

公开(公告)日：2002-09-06

申请号：PCT/US2002/006112

申请日：2002-02-28

Applicant: DADE MICROSCAN INC.

Inventor： FARINA, Edward, Francis ,  FERGUSON, Samuel, Garfield, Jr. ,  GEBRIAN, Peter, Louis ,  KRUFKA, Frank, Stephen ,  MAZZA, John, Charles ,  SHMEL, Nicholas, Michael, Jr.

IPC: C12M1/34

CPC classification number: B01L3/502707 ,  B01L3/502723 ,  B01L2200/0684 ,  B01L2200/142 ,  B01L2300/0864 ,  B01L2400/049

Abstract: A microbiological test array (12) with a generally flat base (11) having a plurality of upwardly projecting microwells (44) connected by a microchannel (42) to an open reservoir (50) formed in a top surface (13) generally parallel to the base (11) of the test array (12). The reservoir (50) has an opening to permit an inoculum-broth liquid solution to flow from the reservoir through the microchannel (51), to a sacrificial evaporation well (46) having an air vent port (48) adapted to control a vacuum filling process, and subsequently to be distributed into each of the plurality of microwells (44).

Abstract translation: 具有大致平坦的基部（11）的微生物测试阵列（12）具有多个向上突出的微孔（44），所述多个向上突出的微孔（44）通过微通道（42）连接到形成在顶表面（13）中的大致平行于 测试阵列（12）的基座（11）。 储存器（50）具有开口以允许接种物液体溶液从储存器流过微通道（51）到具有适于控制真空填充物的排气口（48）的牺牲蒸发井（46） 过程，并随后分配到多个微孔（44）的每一个中。

公开(公告)号：EP1343868A1

公开(公告)日：2003-09-17

申请号：EP02731300.6

申请日：2002-04-08

Applicant: Dade MicroScan Inc.

Inventor： DUNFEE, William, David ,  GEMMELL, Bruce, McLean ,  KAMINSKI, Edward, Stephen ,  MAZZA, John, Charles ,  FARINA, Edward, Francis ,  KRUFKA, Frank, Stephen

IPC: C12M1/34 ,  C12Q1/18 ,  G01N21/00 ,  G01N21/03 ,  G01N35/00 ,  G01N35/02

CPC classification number: G01N21/253 ,  G01N35/00029 ,  G01N35/025 ,  G01N2035/00049 ,  G01N2035/00148

Abstract: Performing antibiotic testing on samples contained in test arrays by orienting the arrays relative to the direction of gravity so that test solution within the microwells is drawn downwards and air within the microwells is forced to the uppermost portion of the test array. Antibiotic testing is conducted using an interrogating beam of radiation passing horizontally through the microwells at locations devoid of air bubbles.

公开(公告)号：EP1325306A1

公开(公告)日：2003-07-09

申请号：EP02764179.4

申请日：2002-04-08

Applicant: Dade MicroScan Inc.

Inventor： FARINA, Edward, Francis ,  GEMMELL, Bruce, McLean ,  MAZZA, John, Charles ,  MCVEY, Michael, Taylor ,  KAMINSKI, Edward, Stephen ,  HADDAD, Antoine, Elias ,  GEBRIAN, Peter, Louis

IPC: G01N21/00 ,  G01N9/30 ,  C12M1/34 ,  C12M3/00

CPC classification number: B01L3/5085 ,  B01L7/00 ,  C12M41/36 ,  C12M41/48 ,  G01N35/025 ,  G01N2035/00148 ,  G01N2035/1076

Abstract: A circular shaped rotor (16) to facilitate automated identification testing of microorganisms in a microbiology analyzer (10) having two circular arrays (120,124) of microwells downwardly projecting from the top of the rotor (16) connected to a recessed central region (114) by a plurality of microchannels (118,122) formed in the upper surface and connecting the recessed central portion to the second plurality of microwells; the rotor is further adapted to be rotated by a source of rotational energy and moved throughout the analyzer using troughs (126) formed near its outer diameter.

Abstract translation: 一种圆形转子（16），用于促进微生物学分析仪（10）中微生物的自动识别测试，微生物分析仪具有两个从连接到凹入的中央区域（114）的转子（16）的顶部向下突出的微孔圆形阵列（120,124） 通过形成在所述上表面中并且将所述凹入中央部分连接到所述第二多个微孔的多个微通道（118,122） 转子还适于通过旋转能量源旋转，并且使用在其外径附近形成的槽（126）移动穿过分析仪。

公开(公告)号：EP1335969A1

公开(公告)日：2003-08-20

申请号：EP02731299.0

申请日：2002-04-08

Applicant: Dade MicroScan Inc.

Inventor： FARINA, Edward, Francis ,  KAMINSKI, Edward, Stephen ,  MAZZA, John, Charles ,  GEMMELL, Bruce, McLean ,  DUNFEE, William, David

IPC: C12M1/22 ,  C12M1/34 ,  C12Q1/02 ,  C12Q1/18 ,  C12Q1/24 ,  G01N21/00

CPC classification number: C12Q1/18

Abstract: A microbiological test array with a plurality of microwells connected by a microchannel to a solution reservoir. Subsequent to filling the microwells, the microchannels are sealed to protect the integrity of the solution in the test microwells.