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公开(公告)号:CA2300294C
公开(公告)日:2009-05-26
申请号:CA2300294
申请日:1998-08-07
Applicant: ELECTROSOLS LTD
Inventor: PIRRIE ALASTAIR BRUCE , COFFEE RONALD ALAN
Abstract: A supply pipe (33) supplies a liquid to a comminution site (40) at which the liquid is subjected to an electric field so as to produce charged comminuted material. An electrical discharge electrode (5) produces ions to at least partially electrically discharge the comminuted material. A further electrode (60) spaced from the comminution site (40) by the electrical discharge electrode (50) electrically attracts ions produced by the electrical discharge electrode (50) away from the comminution site (40) until sufficient space charge is built up to divert the ions towards the charged comminuted material to enable the ions at least partially to discharge the comminuted material.
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公开(公告)号:GB2345010B
公开(公告)日:2002-12-31
申请号:GB9827856
申请日:1998-12-17
Applicant: ELECTROSOLS LTD , BATTELLE MEMORIAL INSTITUTE
Inventor: COFFEE RONALD ALAN
IPC: A61M15/08 , A61M11/00 , A61M15/00 , A61M15/02 , B05B5/025 , B05B5/053 , B05B5/16 , B05B12/00 , B05B12/08 , A61M31/00
Abstract: An inhaler has a housing containing a chamber (1a) providing a reservoir (8) for liquid providing an active ingredient to be supplied to a liquid outlet (10a). First and second electrodes are spaced apart (11 and 12) with the first electrode being spaced apart (11 and 12) with the first electrode being provided at or adjacent the liquid outlet (10a). A voltage supply (5, 7) is activated in response to air flowing through an air inlet (30) of the housing to provide a potential difference between the first and second electrodes (11 and 12) to create an electric field for causing comminution of liquid issuing from the liquid supply outlet (10a) to produce a stream of electrically charged comminuted matter for supply to the nasal passages of a user via an outlet (4) of the housing.
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公开(公告)号:AU2002310691A1
公开(公告)日:2002-11-25
申请号:AU2002310691
申请日:2002-05-14
Applicant: KEATES RICHARD , ELECTROSOLS LTD
Inventor: KEATES RICHARD , DAVIES DAVID NEVILLE , ESSEX-LOPRESTI JOHNATHAN , POLLARD MARIE , WAN MARGARET , COFFEE RONALD ALAN
IPC: A61K9/00 , A61L27/52 , A61L27/54 , B05B5/025 , B05B5/08 , G02B1/04 , A61L26/00 , B05B5/16 , B05B5/043 , B29D11/00 , A61M11/00 , B05B5/053 , G02C7/04
Abstract: An eye covering (700) for covering an exposed surface portion of an eye, the covering comprising a body having front and rear surfaces (702a and 701a) with the rear surface being shaped to conform to said exposed surface portion (701, 702) and at least a portion of the body comprising biologically compatible polymer fibre.
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公开(公告)号:GB2373439A
公开(公告)日:2002-09-25
申请号:GB0116363
申请日:2001-07-04
Applicant: ELECTROSOLS LTD
Inventor: ESSEX-LOPRESTI JOHNATHAN , DAVIES DAVID NEVILLE , COFFEE RONALD ALAN
Abstract: A method of manufacturing a dosage form comprises supplying a liquid comprising a solution of a biologically compatible polymer to a liquid supply tube 2 having an outlet 2a and establishing an electrical field between the outlet 2a and a surface 19 spaced from the outlet to cause liquid issuing from the outlet to form a jet which dries to form a polymer fibre. The fibre deposits onto the surface to form a dosage form body consisting of the fibre. The fibre dissolves or disintegrates in a wet environment such as the mouth. The solution contains a suspension of particulate material that is insoluble in the polymer and the fibre formed contains particles of the particulate material; alternatively, a first fibre layer is formed from the polymer fibre, a region of active ingredient containing material is formed on this layer and a second layer of polymer fibre is formed over the active ingredient region; alternatively effervescent material is incorporated in the dosage form; alternatively a suspension of particulate active material is contained in the polymer solution and polymer droplets containing particles of the active material are formed from the jet. Suitable polymers include vinylpyrrolidone vinylimidazole copolymer, vinylpyrrolidone vinylacetate copolymer, polyvinlyacetate and polycarprolactone. The dosage forms may be encapsulated in another polymer that is not dissolvable in the mouth such as ethyl cellulose.
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公开(公告)号:CA2394664A1
公开(公告)日:2000-06-22
申请号:CA2394664
申请日:1999-12-17
Applicant: ELECTROSOLS LTD
Inventor: COFFEE RONALD ALAN , DAVIES DAVID NEVILLE , PIRRIE ALASTAIR BRUCE
IPC: A61M15/08 , A61M11/00 , A61M15/00 , A61M15/02 , B05B5/025 , B05B5/053 , B05B5/16 , B05B12/00 , B05B12/08 , C01B13/00 , A61K9/00 , A61M31/00 , H01T23/00 , A61L9/22
Abstract: An inhaler has a housing containing a chamber (1a) providing a reservoir (8) for liquid providing an active ingredient to be supplied to a liquid outlet (10a). First and second electrodes are spaced apart (11 and 12) with the fir st electrode being provided at or adjacent the liquid outlet (10a). A voltage supply (5, 7) is activated in response to air flowing through an air inlet (30) of the housing to provide a potential difference between the first and second electrodes (11 and 12) to create an electric field for causing comminution of liquid issuing from the liquid supply outlet (10a) to produce a stream of electrically charged comminuted matter for supply to the nasal passages of a user via an outlet (4) of the housing.
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