A DISPENSING DEVICE
    51.
    发明专利

    公开(公告)号:CA2300294C

    公开(公告)日:2009-05-26

    申请号:CA2300294

    申请日:1998-08-07

    Abstract: A supply pipe (33) supplies a liquid to a comminution site (40) at which the liquid is subjected to an electric field so as to produce charged comminuted material. An electrical discharge electrode (5) produces ions to at least partially electrically discharge the comminuted material. A further electrode (60) spaced from the comminution site (40) by the electrical discharge electrode (50) electrically attracts ions produced by the electrical discharge electrode (50) away from the comminution site (40) until sufficient space charge is built up to divert the ions towards the charged comminuted material to enable the ions at least partially to discharge the comminuted material.

    A delivery device
    52.
    发明专利

    公开(公告)号:GB2345010B

    公开(公告)日:2002-12-31

    申请号:GB9827856

    申请日:1998-12-17

    Abstract: An inhaler has a housing containing a chamber (1a) providing a reservoir (8) for liquid providing an active ingredient to be supplied to a liquid outlet (10a). First and second electrodes are spaced apart (11 and 12) with the first electrode being spaced apart (11 and 12) with the first electrode being provided at or adjacent the liquid outlet (10a). A voltage supply (5, 7) is activated in response to air flowing through an air inlet (30) of the housing to provide a potential difference between the first and second electrodes (11 and 12) to create an electric field for causing comminution of liquid issuing from the liquid supply outlet (10a) to produce a stream of electrically charged comminuted matter for supply to the nasal passages of a user via an outlet (4) of the housing.

    Dosage forms comprising dissolvable fibres

    公开(公告)号:GB2373439A

    公开(公告)日:2002-09-25

    申请号:GB0116363

    申请日:2001-07-04

    Abstract: A method of manufacturing a dosage form comprises supplying a liquid comprising a solution of a biologically compatible polymer to a liquid supply tube 2 having an outlet 2a and establishing an electrical field between the outlet 2a and a surface 19 spaced from the outlet to cause liquid issuing from the outlet to form a jet which dries to form a polymer fibre. The fibre deposits onto the surface to form a dosage form body consisting of the fibre. The fibre dissolves or disintegrates in a wet environment such as the mouth. The solution contains a suspension of particulate material that is insoluble in the polymer and the fibre formed contains particles of the particulate material; alternatively, a first fibre layer is formed from the polymer fibre, a region of active ingredient containing material is formed on this layer and a second layer of polymer fibre is formed over the active ingredient region; alternatively effervescent material is incorporated in the dosage form; alternatively a suspension of particulate active material is contained in the polymer solution and polymer droplets containing particles of the active material are formed from the jet. Suitable polymers include vinylpyrrolidone vinylimidazole copolymer, vinylpyrrolidone vinylacetate copolymer, polyvinlyacetate and polycarprolactone. The dosage forms may be encapsulated in another polymer that is not dissolvable in the mouth such as ethyl cellulose.

    Processes
    55.
    发明专利

    公开(公告)号:GB0123549D0

    公开(公告)日:2001-11-21

    申请号:GB0123549

    申请日:2001-10-01

    Dosage forms
    56.
    发明专利

    公开(公告)号:GB0122399D0

    公开(公告)日:2001-11-07

    申请号:GB0122399

    申请日:2001-09-17

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