公开(公告)号：WO02092142A3

公开(公告)日：2003-01-03

申请号：PCT/GB0202240

申请日：2002-05-14

Applicant: ELECTROSOLS LTD ,  KEATES RICHARD ,  COFFEE RONALD ALAN ,  ESSEX-LOPRESTI JOHNATHAN ,  DAVIES DAVID NEVILLE ,  WAN MARGARET ,  POLLARD MARIE

Inventor： KEATES RICHARD ,  COFFEE RONALD ALAN ,  ESSEX-LOPRESTI JOHNATHAN ,  DAVIES DAVID NEVILLE ,  WAN MARGARET ,  POLLARD MARIE

IPC: A61K9/00 ,  A61L27/52 ,  A61L27/54 ,  B05B5/025 ,  B05B5/08 ,  G02B1/04 ,  A61L26/00 ,  A61M11/00 ,  B05B5/043 ,  B05B5/053 ,  B05B5/16 ,  B29D11/00 ,  G02C7/04

CPC classification number: A61L27/54 ,  A61K9/0051 ,  A61L27/52 ,  A61L2300/402 ,  A61L2300/406 ,  A61L2300/41 ,  A61L2300/414 ,  A61L2430/16 ,  B05B5/025 ,  B05B5/08 ,  B05B5/084 ,  G02B1/043

Abstract: An eye covering (700) for covering an exposed surface portion of an eye, the covering comprising a body having front and rear surfaces (702a and 701a) with the rear surface being shaped to conform to said exposed surface portion (701, 702) and at least a portion of the body comprising biologically compatible polymer fibre.

Abstract translation: 一种用于覆盖眼睛的暴露表面部分的眼罩（700），所述覆盖物包括具有前表面和后表面（702a和701a）的本体，其后表面被成形为符合所述暴露表面部分（701,702）和 身体的至少一部分包含生物相容的聚合物纤维。

公开(公告)号：CA2372657C

公开(公告)日：2008-04-15

申请号：CA2372657

申请日：2000-05-05

Applicant: ELECTROSOLS LTD

Inventor： DAVIES DAVID NEVILLE ,  COFFEE RONALD ALAN ,  PIRRIE ALASTAIR BRUCE

IPC: A61J3/07 ,  A61J3/10 ,  A23G1/00 ,  A23G1/42 ,  A23G3/00 ,  A61J3/00 ,  A61J3/06 ,  A61K9/00 ,  A61K9/20

Abstract: Consumable or dissolvable tablets are manufactured by: supplying a liquid containing a biodissolvable carrier to an outlet (41); establishing an electric field between the outlet (41) and a support surface (6) to cause liquid issuing from the outlet to form at least one fibre or fibrils of the biodissolvable carrier which fibre or fibrils deposit(s) onto the surface to form a fibre web or mat; separating the web or mat into a plurality of individual tablets; and incorporating at least on e active ingredient on or in the tablets.

公开(公告)号：CA2372657A1

公开(公告)日：2000-11-16

申请号：CA2372657

申请日：2000-05-05

Applicant: ELECTROSOLS LTD

Inventor： DAVIES DAVID NEVILLE ,  PIRRIE ALASTAIR BRUCE ,  COFFEE RONALD ALAN

IPC: A61J3/07 ,  A61J3/00 ,  A61J3/06 ,  A61K9/00 ,  A61K9/20 ,  A61J3/10

Abstract: Consumable or dissolvable tablets are manufactured by: supplying a liquid containing a biodissolvable carrier to an outlet (41); establishing an electric field between the outlet (41) and a support surface (6) to cause liquid issuing from the outlet to form at least one fibre or fibrils of the biodissolvable carrier which fibre or fibrils deposit(s) onto the surface to form a fibre web or mat; separating the web or mat into a plurality of individual tablets; and incorporating at least one active ingredient on or i n the tablets.

公开(公告)号：AU2002310691A1

公开(公告)日：2002-11-25

申请号：AU2002310691

申请日：2002-05-14

Applicant: KEATES RICHARD ,  ELECTROSOLS LTD

Inventor： KEATES RICHARD ,  DAVIES DAVID NEVILLE ,  ESSEX-LOPRESTI JOHNATHAN ,  POLLARD MARIE ,  WAN MARGARET ,  COFFEE RONALD ALAN

IPC: A61K9/00 ,  A61L27/52 ,  A61L27/54 ,  B05B5/025 ,  B05B5/08 ,  G02B1/04 ,  A61L26/00 ,  B05B5/16 ,  B05B5/043 ,  B29D11/00 ,  A61M11/00 ,  B05B5/053 ,  G02C7/04

Abstract: An eye covering (700) for covering an exposed surface portion of an eye, the covering comprising a body having front and rear surfaces (702a and 701a) with the rear surface being shaped to conform to said exposed surface portion (701, 702) and at least a portion of the body comprising biologically compatible polymer fibre.

公开(公告)号：GB2373439A

公开(公告)日：2002-09-25

申请号：GB0116363

申请日：2001-07-04

Applicant: ELECTROSOLS LTD

Inventor： ESSEX-LOPRESTI JOHNATHAN ,  DAVIES DAVID NEVILLE ,  COFFEE RONALD ALAN

IPC: A61J3/00 ,  A61J3/06 ,  A61J3/07 ,  A61K9/00 ,  A61K9/70

Abstract: A method of manufacturing a dosage form comprises supplying a liquid comprising a solution of a biologically compatible polymer to a liquid supply tube 2 having an outlet 2a and establishing an electrical field between the outlet 2a and a surface 19 spaced from the outlet to cause liquid issuing from the outlet to form a jet which dries to form a polymer fibre. The fibre deposits onto the surface to form a dosage form body consisting of the fibre. The fibre dissolves or disintegrates in a wet environment such as the mouth. The solution contains a suspension of particulate material that is insoluble in the polymer and the fibre formed contains particles of the particulate material; alternatively, a first fibre layer is formed from the polymer fibre, a region of active ingredient containing material is formed on this layer and a second layer of polymer fibre is formed over the active ingredient region; alternatively effervescent material is incorporated in the dosage form; alternatively a suspension of particulate active material is contained in the polymer solution and polymer droplets containing particles of the active material are formed from the jet. Suitable polymers include vinylpyrrolidone vinylimidazole copolymer, vinylpyrrolidone vinylacetate copolymer, polyvinlyacetate and polycarprolactone. The dosage forms may be encapsulated in another polymer that is not dissolvable in the mouth such as ethyl cellulose.

公开(公告)号：CA2394664A1

公开(公告)日：2000-06-22

申请号：CA2394664

申请日：1999-12-17

Applicant: ELECTROSOLS LTD

Inventor： COFFEE RONALD ALAN ,  DAVIES DAVID NEVILLE ,  PIRRIE ALASTAIR BRUCE

IPC: A61M15/08 ,  A61M11/00 ,  A61M15/00 ,  A61M15/02 ,  B05B5/025 ,  B05B5/053 ,  B05B5/16 ,  B05B12/00 ,  B05B12/08 ,  C01B13/00 ,  A61K9/00 ,  A61M31/00 ,  H01T23/00 ,  A61L9/22

Abstract: An inhaler has a housing containing a chamber (1a) providing a reservoir (8) for liquid providing an active ingredient to be supplied to a liquid outlet (10a). First and second electrodes are spaced apart (11 and 12) with the fir st electrode being provided at or adjacent the liquid outlet (10a). A voltage supply (5, 7) is activated in response to air flowing through an air inlet (30) of the housing to provide a potential difference between the first and second electrodes (11 and 12) to create an electric field for causing comminution of liquid issuing from the liquid supply outlet (10a) to produce a stream of electrically charged comminuted matter for supply to the nasal passages of a user via an outlet (4) of the housing.

公开(公告)号：CA2394664C

公开(公告)日：2009-10-06

申请号：CA2394664

申请日：1999-12-17

Applicant: ELECTROSOLS LTD

Inventor： COFFEE RONALD ALAN ,  PIRRIE ALASTAIR BRUCE ,  DAVIES DAVID NEVILLE

IPC: A61M15/00 ,  A61M15/08 ,  A61K9/00 ,  A61L9/22 ,  A61M11/00 ,  A61M15/02 ,  A61M31/00 ,  B05B5/025 ,  B05B5/053 ,  B05B5/16 ,  B05B12/00 ,  B05B12/08 ,  H01T23/00

Abstract: An inhaler has a housing containing a chamber (la) providing a reservoir (8) for liquid providing an active ingredient to be supplied to a liquid outlet (l0a). First and second electrodes are spaced apart (11 and 12) with the first electrode being provided at or adjacent the liquid outlet (l0a). A voltage supply (5,7) is activated in response to air flowing through an air inlet (30) of the housing to provide a potential difference between the first and second electrodes (11 and 12) to create an electric field for causing comminution of liquid issuing from the liquid supply outlet (10a) to produce a stream of electrically charged comminuted matter for supply to the nasal passages of a user via an outlet (4) of the housing.

公开(公告)号：AU4439101A

公开(公告)日：2001-10-15

申请号：AU4439101

申请日：2001-04-03

Applicant: ELECTROSOLS LTD

Inventor： DAVIES LEE ADRIAN ,  DAVIES DAVID NEVILLE ,  WAN MARGARET ,  COFFEE RONALD ALAN

IPC: A61K9/72 ,  A61K38/48 ,  A61K47/10 ,  A61K47/12 ,  A61K47/18 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61M11/00 ,  A61M13/00 ,  A61M15/00 ,  A61M15/02 ,  A61M15/08 ,  B05B5/025 ,  B05B5/16

Abstract: Methods are described of delivering biological material, which methods include the steps of providing a liquid formulation containing the biological material, supplying the liquid formulation to an outlet and subjecting liquid issuing from the outlet to an electrical field thereby causing electrohydrodynamic processing of the liquid without denaturing the biological material. In one example, the liquid formulation is provided by removing salts from a formulation containing biological material that does not denature in alcohol and then adding an alcohol to the formulation before supplying the liquid formulation to the outlet. An acid may be added to the liquid formulation before supplying the liquid formulation to the outlet.