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公开(公告)号：WO2007011552A3
公开(公告)日：2007-04-05
申请号：PCT/US2006026512
申请日：2006-07-10
Applicant: COLGATE PALMOLIVE CO , MILLER JEFFREY , BOYD THOMAS J , ARVANITIDOU EVANGELIA S , PRENCIPE MICHAEL , MORGAN ANDRE
Inventor： MILLER JEFFREY , BOYD THOMAS J , ARVANITIDOU EVANGELIA S , PRENCIPE MICHAEL , MORGAN ANDRE
Abstract: An oral composition is provided covering one or more cationic active ingredients and a cationic-compatible inorganic particulate having a porous surface that is substantially inert to the cationic active ingredient. The oral composition also has a cationic-compatible surfactant system and a carrier that is stable in the presence of the cationic active ingredient. The oral composition can be provided in a dual tube or single tube form, if desired.
Abstract translation: 提供覆盖一种或多种阳离子活性成分和具有对阳离子活性成分基本惰性的多孔表面的阳离子相容性无机颗粒的口腔组合物。 口服组合物还具有阳离子相容的表面活性剂体系和在阳离子活性成分存在下稳定的载体。 如果需要，口腔组合物可以以双管或单管形式提供。
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公开(公告)号：WO2007011552A2
公开(公告)日：2007-01-25
申请号：PCT/US2006/026512
申请日：2006-07-10
Applicant: COLGATE-PALMOLIVE COMPANY , MILLER, Jeffrey , BOYD, Thomas, J. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael , MORGAN, Andre
Inventor： MILLER, Jeffrey , BOYD, Thomas, J. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael , MORGAN, Andre
Abstract: An oral composition is provided covering one or more cationic active ingredients and a cationic-compatible inorganic particulate having a porous surface that is substantially inert to the cationic active ingredient. The oral composition also has a cationic-compatible surfactant system and a carrier that is stable in the presence of the cationic active ingredient. The oral composition can be provided in a dual tube or single tube form, if desired.
Abstract translation: 提供一种口服组合物，其覆盖一种或多种阳离子活性成分和具有基本上对阳离子活性成分惰性的多孔表面的阳离子相容的无机颗粒。 口服组合物还具有阳离子相容的表面活性剂体系和在阳离子活性成分存在下是稳定的载体。 如果需要，口服组合物可以以双管或单管形式提供。
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公开(公告)号：WO2006071404A1
公开(公告)日：2006-07-06
申请号：PCT/US2005/042163
申请日：2005-11-18
Applicant: COLGATE-PALMOLIVE COMPANY , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
Inventor： ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
CPC classification number: A61K8/97 , A61K2800/43 , A61Q11/00
Abstract: Low water tooth pastes contain a variety of plant extracts. The oral or dentifrice compositions containing humectants, abrasive compounds, and a variety of plant extracts, such as rosemary and green tea extracts, along with an additional antioxidant component. Examples of antioxidants include stannous compounds, sodium meta-bisulfite, BHT, ammonium sulfate, and potassium stannate. The compositions are resistant to browning. The invention also provides methods for promoting oral health of a subject animal comprising applying a composition as discussed above to the oral surfaces of the animal.
Abstract translation: 低水牙膏含有各种植物提取物。 含有湿润剂，磨料化合物和各种植物提取物如迷迭香和绿茶提取物的口服或牙粉组合物以及另外的抗氧化成分。 抗氧化剂的实例包括亚锡化合物，偏亚硫酸氢钠，BHT，硫酸铵和锡酸锡。 组合物耐褐变。 本发明还提供用于促进受试动物的口腔健康的方法，包括将如上所述的组合物施用于动物的口腔表面。
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公开(公告)号：WO2006069210A3
公开(公告)日：2006-06-29
申请号：PCT/US2005/046522
申请日：2005-12-21
Applicant: COLGATE-PALMOLIVE COMPANY , XU, Guofeng , BOYD, Thomas, J. , HAO, Zhigang , VISCIO, David , GAFFAR, Abdul , MELLO, Sarita, V. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
Inventor： XU, Guofeng , BOYD, Thomas, J. , HAO, Zhigang , VISCIO, David , GAFFAR, Abdul , MELLO, Sarita, V. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
IPC: A61Q11/02 , A61Q11/00 , A61K8/19 , A61K8/21 , A61K8/25 , A61K8/27 , A61K8/29 , A61K8/49 , A61K8/81 , A61P29/00
Abstract: Oral care compositions containing: a free-B-ring flavonoid and a flavan; as well as at least one bioavailability-enhancing agent are provided. Methods of using the oral compositions are also provided.
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55.发明申请
公开(公告)号：WO2005037127A1
公开(公告)日：2005-04-28
申请号：PCT/US2004/033502
申请日：2004-10-12
Applicant: COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , CHOPRA, Suman , NORRIS, Joseph, T. , SERRANO, Adolfo
Inventor： PRENCIPE, Michael , CHOPRA, Suman , NORRIS, Joseph, T. , SERRANO, Adolfo
IPC: A61C19/06
CPC classification number: A61C19/066 , A46B9/005 , A46B9/021 , A46B9/025 , A46B11/0024 , A46B11/0027 , A46B17/04 , A46B2200/10 , A46B2200/1046 , A46B2200/20 , A61C1/0092 , A61C3/005 , A61C17/0202 , A61C19/063 , A61K8/22 , A61K8/8147 , A61K2800/87 , A61K2800/92 , A61Q11/00
Abstract: The method of the present invention is directed to the storage and dispensing of a peroxide containing tooth whitening composition. During storage and subsequent use the composition in the storage chamber must be maintained segregated from the applicator surface. This is accomplished by delivering the peroxide containing tooth whitening composition from the storage chamber through a delivery channel having a length and a cross-sectional diameter sufficient to preclude the migration of moisture and the enzyme catalase from the application surface to the storage chamber. The composition is applied to teeth by means of bristles, a sponge surface or fibrillated surface. This applicator can be used with both aqueous and non-aqueous peroxide containing tooth whitening compositions.
Abstract translation: 本发明的方法涉及含过氧化物的牙齿增白组合物的储存和分配。 在储存和随后使用期间，储存室中的组合物必须保持与施用器表面分离。 这是通过将来自储存室的含过氧化物的牙齿增白组合物通过具有足以防止水分和酶过氧化氢酶从施用表面迁移到储存室的长度和横截面直径的输送通道来实现的。 组合物通过刷毛，海绵表面或原纤化表面施加到牙齿上。 该施用器可以与含水和非水过氧化物含有牙齿美白组合物一起使用。
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Patent Agency Ranking
公开(公告)号：WO2013095370A1
公开(公告)日：2013-06-27
申请号：PCT/US2011/066093
申请日：2011-12-20
Applicant: COLGATE-PALMOLIVE COMPANY , FISHER, Steven , COLLIGAN, Mary , PRENCIPE, Michael , TAMBS, Gary
Inventor： FISHER, Steven , COLLIGAN, Mary , PRENCIPE, Michael , TAMBS, Gary
Abstract: Described herein are preservative systems which prevent the growth of microorganisms in silica based dentifrices, compositions comprising the same; and methods of making and using the same.
Abstract translation: 本文描述了防止微生物在二氧化硅基洁牙剂中生长的防腐剂体系，包含它们的组合物; 以及制作和使用它们的方法。
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公开(公告)号：WO2013074080A1
公开(公告)日：2013-05-23
申请号：PCT/US2011/060678
申请日：2011-11-15
Applicant: COLGATE-PALMOLIVE COMPANY , CHEN, Elva , KENNEDY, Sharon , MIRAJKAR, Yelloji-Rao , JOGUN, Suzanne , PRENCIPE, Michael
Inventor： CHEN, Elva , KENNEDY, Sharon , MIRAJKAR, Yelloji-Rao , JOGUN, Suzanne , PRENCIPE, Michael
CPC classification number: A61C19/066 , A46B11/0055 , A46B2200/1066 , A61C17/0202 , A61C17/0217 , A61K8/042 , A61K8/73 , A61K8/731 , A61K49/0073 , A61K2800/45 , A61K2800/872 , A61Q11/00
Abstract: The invention provides an oral care system comprising a gel in a pen dispenser, the dispenser comprising a chamber which permits dispensing of a measured amount of the gel, wherein the gel exhibits a Herschel-Bulkley yield stress of 10 to 230 dynes/cm2, a Herschel-Bulkley viscosity of 3 to 500 poise, and a Herschel-Bulkley rate index of 0.4 to 0.6, the specific viscosity permitting efficient application of the gel, as well as methods of using the same.
Abstract translation: 本发明提供了一种包括笔分配器中的凝胶的口腔护理系统，该分配器包括允许分配测量量的凝胶的腔室，其中凝胶呈现10至230达因/厘米2的赫歇尔 - 帕利利屈服应力， Herschel-Bulkley粘度为3至500泊，Herschel-Bulkley速率指数为0.4至0.6，允许有效应用凝胶的比粘度，以及使用该凝胶的方法。
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公开(公告)号：WO2013074079A1
公开(公告)日：2013-05-23
申请号：PCT/US2011/060676
申请日：2011-11-15
Applicant: COLGATE-PALMOLIVE COMPANY , CHEN, Elva , KENNEDY, Sharon , MIRAJKAR, Yelloji-Rao , JOGUN, Suzanne , PRENCIPE, Michael
Inventor： CHEN, Elva , KENNEDY, Sharon , MIRAJKAR, Yelloji-Rao , JOGUN, Suzanne , PRENCIPE, Michael
CPC classification number: A61K8/042 , A61K8/345 , A61K8/466 , A61K8/498 , A61K8/73 , A61K8/731 , A61K2800/45 , A61Q11/00
Abstract: The invention provides an orally acceptable plaque indicator gel comprising a dye in sufficient concentration to visibly stain plaque upon application, optionally for use in combination with an orally acceptable plaque removal gel comprising an antiplaque agent in sufficient concentration to remove plaque and or kill bacteria upon application, in each case the gel having a specific viscosity permitting efficient application using a pen dispenser, as well as reduced dye or antiplaque agent concentration, together with methods of using the same.
Abstract translation: 本发明提供了一种口腔可接受的斑块指示凝胶，其包含足够浓度的染料以在施用时明显地染色斑块，任选地与口腔可接受的斑块去除凝胶组合使用，其包含足够浓度的抗牙斑剂以在施用时除去斑块和/或杀死细菌 在每种情况下，凝胶具有允许使用笔式分配器有效应用的特定粘度，以及降低的染料或抗斑剂剂浓度，以及使用该浓度的方法。
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公开(公告)号：WO2012087288A3
公开(公告)日：2012-12-27
申请号：PCT/US2010061414
申请日：2010-12-21
Applicant: COLGATE PALMOLIVE CO , PORTER VENDA , PATEL VYOMA , FISHER STEVEN WADE , MORGAN ANDRE MICHELLE , PRENCIPE MICHAEL , JARACZ STANISLAV
Inventor： PORTER VENDA , PATEL VYOMA , FISHER STEVEN WADE , MORGAN ANDRE MICHELLE , PRENCIPE MICHAEL , JARACZ STANISLAV
CPC classification number: A61K8/58 , A61K8/24 , A61K8/27 , A61K8/36 , A61K8/361 , A61K8/362 , A61K8/365 , A61K8/44 , A61Q11/00
Abstract: Described herein are compositions comprising combinations of metal salts, and methods of preparing and using the same.
Abstract translation: 本文描述的是包含金属盐的组合的组合物，以及制备和使用它们的方法。
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公开(公告)号：WO2010141693A3
公开(公告)日：2012-12-27
申请号：PCT/US2010037220
申请日：2010-06-03
Applicant: COLGATE PALMOLIVE CO , PORTER VENDA , MORGAN ANDRE , JARACZ STANISLAV , GRONLUND JENNIFER , XU GUOFENG , WU DONGHUI , PRENCIPE MICHAEL , SUBRAMANYAM RAVI
Inventor： PORTER VENDA , MORGAN ANDRE , JARACZ STANISLAV , GRONLUND JENNIFER , XU GUOFENG , WU DONGHUI , PRENCIPE MICHAEL , SUBRAMANYAM RAVI
CPC classification number: A61Q11/00 , A61K8/58 , A61K31/69 , A61Q17/005 , Y10S514/835
Abstract: A stabilized oral care composition comprising a borinic acid derivative, e.g., a borinic ester.
Abstract translation: 一种稳定的口腔护理组合物，其包含硼酸衍生物，例如硼酸酯。
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