Abstract:
PURPOSE: A cosmetic composition containing melanin for preventing and relieving skin irritation is provided to regulate the expression of inflammatory cytokine and to prevent and treat skin irritation such as dermatitis, skin dryness, smarting, itching, and burning sensation. CONSTITUTION: A cosmetic composition for preventing and treating skin irritation contains 0.01-10 wt% of melanin as an active ingredient. Melanin is derived from a Mucuna pruriens extract. Melanin suppresses the expression of inflammatory cytokine by all-trans retinoic acid. Melanin is prepared by pretreating the Mucuna pruriens extract at pH 8-10 and oxidizing at 15-35 deg. C. for 3-5 days. The cosmetic composition is manufactured in the form of a lotion, a nutrition cream, a massage cream, an essence, an eye cream, a cleansing foam, a pack, or a body lotion. [Reference numerals] (AA) MCP-1 expressed amount(pg/ml); (BB) 500ppm, embodiment 1; (CC) 100ppm, embodiment 2; (DD) 1ppm comparative embodiment 1; (EE) 1uM comparative embodiment 2; (FF) Control group
Abstract:
PURPOSE: A method for preparing lipid-coated hydrogel particles is provided to prevent reduction of sealing efficiency of a drug. CONSTITUTION: A method for preparing lipid-coated hydrogel particles comprises: a step of preparing hydrogel particles using water soluble polymers and water soluble crosslinking agent; a step of dissolving the lipid in organic solvent; a step of dispersing the hydrogel particles to the organic solvent; and a step of adding water to the dispersed liquid and performing reduced pressure distillation. The organic solvent is main organic solvent or alcohol of C1-C6.
Abstract:
PURPOSE: A composition for preventing or treating acne is provided to ensure high stability and excellent usability. CONSTITUTION: A composition for preventing or treating acne contains 0.001-50 weight% of benzoyl peroxide, derivative thereof, hydrous form, or pharmaceutically salt thereof; 0.001-50 weight% of clindamycin, derivative thereof, hydrous form, or pharmaceutically acceptable salt thereof; and 0.01-10 weight% of sodium pyrosulfite.
Abstract:
PURPOSE: A composition containing Phellodendri Cortex extract is provided to suppress acne pigmentation in a cosmetic, food, or medical field. CONSTITUTION: A composition for suppressing pigmentation by acne contains 0.5-20 weight% of Phellodendri Cortex extract as an active ingredient. An external use skin composition contains the composition for suppressing pigmentation. The composition is a cosmetic formulation. A composition for aftercare of acne contains Phellodendri Cortex extract as an active ingredient. A food additive or health food composition contains the composition for suppressing pigmentation or aftercare.
Abstract:
PURPOSE: A composition containing Glycyrrhiza Uralensis Fischer extract is provided to suppress pigmentation and/or scar by acne and to be used in cosmetic or medical field. CONSTITUTION: A composition for suppressing pigmentation or scar by acne contains Glycyrrhiza Uralensis Fischer extract as an active ingredient. The Glycyrrhiza Uralensis Fischer extract suppresses gelatinase. An external use composition contains the composition for suppressing pigmentation or scar. The composition is a cosmetic formulation. An aftercare composition for acne sequel contains Glycyrrhiza Uralensis Fischer extract as an active ingredient.
Abstract:
PURPOSE: A composition containing Saururus chinensis extract is provided to suppress pigmentation and/or scar. CONSTITUTION: A composition for preventing pigmentation or scar by acne contains 0.5-2.0 weight% of Saururus chinensis extract. An external use skin composition contains the composition for preventing pigmentation or scar by acne. The composition is a cosmetic formulation. A food additive or health food composition contains the composition for preventing pigmentation or scar or after care composition.
Abstract:
PURPOSE: A skin external composition for preventing or treating inflammatory dermatitis containing natural products is provided to ensure anti-inflammation and skin moisturization. CONSTITUTION: A skin external composition for preventing or treating inflammatory dermatitis contains 0.001-20 weight% of green tea, 0.05-3 weight% of sophora root, 0.05-3 weight% of Portulaca oleracea L., and 0.5-30 weight% of Polygonatum officinale as active ingredient. The skin external composition additionally contains 1-50 weight% of starch, 1-10 weight% of cacao bean, 1-10 weight% of Cnidii Rhizoma or 0.5-5 weight% of Angelicae gigantis Radix. The composition is cosmetic composition or pharmaceutical composition.