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公开(公告)号：KR1020080110943A
公开(公告)日：2008-12-22
申请号：KR1020050102895
申请日：2005-10-31
Applicant: (주)아모레퍼시픽
IPC: A61K31/335 , A61P19/02 , A61K8/49
Abstract: A composition for promoting the generation of hyaluronic acid containing Musk T is provided to realize the prevention and treatment of the degenerative arthritis. A composition for promoting the generation of hyaluronic acid contains Musk T with the concentration of 1.0 ~ 10 mug/ml as an active ingredient. The composition is for the oral or external use. The composition for treating degenerative arthritis contains a composition for promoting the generation of hyaluronic acid. A skin anti-aging composition contains a composition for promoting the generation of hyaluronic acid.
Abstract translation: 提供了用于促进含有Musk T的透明质酸的产生的组合物，以实现对退行性关节炎的预防和治疗。 用于促进透明质酸产生的组合物含有浓度为1.0〜10ug / ml的Musk T作为活性成分。 组合物用于口服或外用。 用于治疗退行性关节炎的组合物含有促进透明质酸产生的组合物。 皮肤抗衰老组合物含有促进透明质酸产生的组合物。
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公开(公告)号：KR100867596B1
公开(公告)日：2008-11-10
申请号：KR1020070034924
申请日：2007-04-10
Applicant: (주)아모레퍼시픽
IPC: G01N33/48 , G01N33/533
Abstract: 본 발명은 피부 각질 박리량을 정량할 수 있는 평가법으로서, 기존의 형광염색을 통해 육안적으로 각질 박리량을 평가하는 부분을 개선하여 이미지 분석 프로그램을 이용함으로써 각질박리량을 수치화하고, 객관적으로 각질 박리량을 검증할 수 있는 방법에 관한 것이다. 보다 상세하게는 피부 표면의 각질층을 형광염색시약으로 염색한 다음, 형광염색된 피부 표면에 각질 박리용 시료를 도포한 후 사진을 촬영하여 형광이미지를 얻음으로써 추적 관찰을 실시하고, 촬영한 사진의 형광이미지는 이미지 분석 프로그램을 이용함으로써 형광강도를 수치화하고, 형광이미지를 이용하여 3차원 이미지화 할 수 있다. 이를 통해 기존의 육안 판정에 의존하던 각질 박리 평가를 수치적으로 객관화 할 수 있으며, 3차원 이미지 변환을 통해 각질 박리 효과를 가시화 할 수 있다.
각질 박리, 형광염색, 댄실 클로라이드(Dansyl chloride), 디히드록시아세톤(Dihydroxyacetone), 이미지 분석, 형광강도, 흑백 전환-
公开(公告)号：KR1020080091901A
公开(公告)日：2008-10-15
申请号：KR1020070034924
申请日：2007-04-10
Applicant: (주)아모레퍼시픽
IPC: G01N33/48 , G01N33/533
Abstract: A method for measuring the amount of human stratum corneum exfoliation is provided to digitize the stratum corneum exfoliation amount using an image analysis program by improving a conventional technique of evaluating the stratum corneum exfoliation amount visually through fluorescence staining, thereby verifying the stratum corneum amount objectively. A method for measuring the amount of human stratum corneum exfoliation comprises the steps of: (a) coating a fluorescent staining sample such as Dansyl chloride and dihydroxyacetone on a stratum corneum of skin surface for fluorescence-staining; (b) coating a sample for exfoliation such as glycolic acid, lactic acid, malic acid, citric acid, tartaric acid, salicylic acid and papain enzyme on the fluorescent-stained stratum corneum for 4-14 days to perform exfoliation; (c) fluorescence-photographing the exfoliated stratum corneum to obtain a fluorescent image; and (d) setting up an analysis area of the fluorescent image and digitizing fluorescence strength of the analysis by using an image analysis program. Further, the step (a) of coating a fluorescent staining sample is performed for 6 hrs.
Abstract translation: 提供了用于测量人角质层脱落量的方法，通过改进通过荧光染色目视评估角质层剥离量的常规技术，通过图像分析程序对角质层去角质量进行数字化，从而客观地验证角质层数量。 用于测量人角质层剥离量的方法包括以下步骤：（a）将荧光染色样品如丹酰氯和二羟基丙酮涂覆在皮肤表面的角质层上用于荧光染色; （b）在荧光染色的角质层上涂覆乙醇酸，乳酸，苹果酸，柠檬酸，酒石酸，水杨酸和木瓜蛋白酶等剥离性样品4-14天，进行剥离; （c）荧光拍摄剥离的角质层以获得荧光图像; 和（d）通过使用图像分析程序设置荧光图像的分析区域和数字化分析的荧光强度。 此外，涂布荧光染色样品的步骤（a）进行6小时。
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公开(公告)号：KR1020050052839A
公开(公告)日：2005-06-07
申请号：KR1020030086405
申请日：2003-12-01
Applicant: (주)아모레퍼시픽
IPC: A61K36/26 , A61K36/535 , A61P17/00
CPC classification number: A61K36/268 , A61K9/06 , A61K36/36 , A61K36/535 , A61K36/71 , A61K36/81 , A61K2300/00 , Y10S514/861 , Y10S514/863
Abstract: 본 발명은 생약재 추출물을 함유하는 피부 외용제 조성물에 관한 것으로, 더욱 상세하게는, 세신(
Asiasari Radix ), 소엽(
Perillae Herba ), 소자(
Perillae Semen ), 승마(
Cimicifugae Rhizoma ), 왕불유행(
Melandrii Herba ), 용규(
Solani Nigri Herba ), 우방자(
Arctii Semen ), 위릉채(
Potentillae Radix ), 육계(
Cinnamomi Cortex Spissus ), 적복령(
Hoelen rubra ), 적소두(
Phaseoli angularis Semen ), 초과(
Ammomi Tsao-ko Frucuts ), 초두구(
Alpiniae Katsumadaii Semen ), 메밀(
Fagopyrum esculentum ), 명아주(
Chenopodium album var. centrorubrum ), 범꼬리(
Bistorta manshuriensis ), 상사화(
Lycoris squamigera ), 섬백리향(
Thymus quinquecostatus var. japonica ), 쑥방망이(
Senecio argunensis ) 및 참나물(
Pimpinella brachycarpa ) 중에서 선택된1종 이상의 생약재 추출물을 유효성분으로 함유하는 피부 외용제로서, T 임파구 매개성 면역반응 억제능력에 의해 아토피성 피� �염, 접촉성 피부염, 건선 등의 피부질환을 치료 또는 예방하기 위해 사용될 수 있다.-
公开(公告)号：KR1020040071963A
公开(公告)日：2004-08-16
申请号：KR1020030007885
申请日：2003-02-07
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/981 , A61K2800/75 , A61Q19/00 , Y10S514/857
Abstract: PURPOSE: A composition containing musk having effects of strengthening the formation and maintenance of a natural moisturizing factor present in the stratum corneum of the skin and naturally increasing synthesis of lipid between cells is provided. It can be used as a therapeutic agent for preventing skin diseases such as atopic contact dermatitis as well as xeroderma or improving its symptoms. CONSTITUTION: The composition for external for improving the drying of the skin is characterized in that it contains 0.0001 to 20% by weight of musk as an effective ingredient, based on the total weight of the composition. The musk is musk 781 or musk T. The improvement in drying of the skin contains inducing the cell growth of keratinocyte, recovering a skin barrier, promoting the expression of filaggrin, activating PPAR(Peroxisome Proliferator Activated Receptor)-α, increasing biosynthesis of ceramide, improving skin moisturization, preventing atopic, contact dermatitis or improving its symptoms.
Abstract translation: 目的：提供一种含有麝香的组合物，其具有加强皮肤角质层中天然保湿因子的形成和维持的作用，并且天然增加细胞之间的脂质合成。 它可以用作预防皮肤疾病如特应性接触性皮炎以及干性皮炎或改善其症状的治疗剂。 构成：用于改善皮肤干燥的外用组合物的特征在于，基于组合物的总重量，其含有0.0001至20重量％的麝香作为有效成分。 麝香是麝香781或麝香T.皮肤干燥的改善包括诱导角质形成细胞的细胞生长，恢复皮肤屏障，促进丝聚蛋白的表达，激活PPAR（过氧化物酶体增殖物激活受体）-α，增加神经酰胺的生物合成 改善皮肤保湿，预防特应性，接触性皮炎或改善其症状。
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Patent Agency Ranking
公开(公告)号：KR1020040058848A
公开(公告)日：2004-07-05
申请号：KR1020020085361
申请日：2002-12-27
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/342 , A61K9/0014 , A61K2236/331 , A61K2236/51 , Y10S514/857
Abstract: PURPOSE: Provided is a composition of external application to the skin containing extract of Adenophorea radix, thereby preventing dryness of the skin, improving moisture retaining property of the skin, and preventing and treating atopic dermatitis and skin inflammation. CONSTITUTION: A composition of external application to the skin is characterized by containing, as an active ingredient, 0.0001-60 wt.% of extract of Adenophorea radix. The composition moisturizes the skin, improves atopic dermatitis or skin inflammation, facilitates the differentiation of keratinocyte and expression of filaggrin, promotes the generation of ceramide, and activates PPAR-alpha.
Abstract translation: 目的：提供外用于含有Adenophorea根的提取物的皮肤的组合物，从而防止皮肤干燥，改善皮肤的保湿性，以及预防和治疗特应性皮炎和皮肤炎症。 构成：外用于皮肤的组合物的特征在于含有0.0001-60重量％的Adenophorea根的提取物作为活性成分。 组合物润湿皮肤，改善特应性皮炎或皮肤炎症，促进角质形成细胞的分化和丝聚蛋白的表达，促进神经酰胺的产生，并激活PPAR-α。
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公开(公告)号：KR101493316B1
公开(公告)日：2015-02-16
申请号：KR1020080070986
申请日：2008-07-22
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 기호성이 우수한 다리 부종 개선용 기능성 차에 관한 것으로서, 보다 상세하게는 다리 부종의 예방 및 완화 효과를 나타내는 적포도잎 추출물(Red Vine Leaf Extract)과 녹차 추출분말, 과실 추출분말, 과실향, 당류, 비타민 및 미네랄을 혼합함으로써 적포도잎 추출물 특유의 떫은맛을 마스킹하고 달콤한 맛과 향을 첨가하여 다리 부종 개선 효과뿐만 아니라 우수한 기호성을 갖는 기능성 차에 관한 것이다.
적포도잎추출물*녹차추출분말*과실추출분말*과실향*당류*비타민*미네랄*다리부종*기능성차-
58.发明公开
公开(公告)号：KR1020140122533A
公开(公告)日：2014-10-20
申请号：KR1020130039328
申请日：2013-04-10
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 황기 부정근의 대량생산방법에 관한 것으로서, (a)황기 종자를 멸균하여 무균화하는 단계; (b)상기 무균화된 황기 종자의 발아를 유도하는 단계; (c)발아된 황기로부터 식물호르몬을 사용하여 부정근을 유도하는 단계; (d)상기 유도된 부정근을 액체배양하는 단계;및 (e)상기 배양된 부정근을 엘리시터(Elicitor)로 처리하고 생물반응기(Bioreactor)에서 배양하는 단계를 포함함으로써 아스트라갈로사이드 IV(Astragaloside IV)의 함량을 현저히 증가시킨 황기 부정근을 대량으로 생산할 수 있다.
Abstract translation: 本发明涉及一种大规模生产黄芪不定根的方法。 该方法包括：（a）通过对黄芪的种子进行灭菌来除去微生物的步骤; （b）诱导灭菌的黄芪种子发芽的步骤; （c）使用植物激素从发芽的黄芪中诱导不定根的步骤; （d）液体培养诱导的不定根的步骤; 和（e）用激发剂处理培养的不定根并在生物反应器中孵育的步骤，从而能够大规模生产黄芪的黄芪甲苷IV不定根。
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公开(公告)号：KR1020130078387A
公开(公告)日：2013-07-10
申请号：KR1020110147304
申请日：2011-12-30
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/82
Abstract: PURPOSE: A composition containing a Camellia sinensis leaf extract, a Camellia sinensis flower extract, and a Camellia sinensis seed extract as active ingredients is provided to activate AMP-activated protein kinase (AMPK), to suppress fatty acid synthesis, and to promote fatty acid oxidation and glucose absorption, thereby preventing and treating metabolic syndrome. CONSTITUTION: A composition for preventing or treating metabolic syndrome contains a Camellia sinensis leaf extract, a Camellia sinensis flower extract, and a Camellia sinensis seed extract as active ingredients, in a weight ratio of 4-12:0.3-4:0.3-4. The composition contains the Camellia sinensis leaf extract and the Camellia sinensis flower and seed extracts in a weight ratio of 4-12:0.2-8. The metabolic syndrome is a glucoside metabolic syndrome or a lipid metabolic syndrome. The metabolic syndrome includes one or more among obesity, hyperlipidemia, type 2 diabetes, arteriosclerosis, myocardial infarction, and angina pectoris. The composition is a pharmaceutical composition. [Reference numerals] (AA) Mixture of Camellia sinensis leaf, flower, and seed extracts; (BB) Camellia sinensis flower extract; (CC) Camellia sinensis seed extract; (DD) Camellia sinensis leaf extract
Abstract translation: 目的：提供含有山茶叶提取物，山茶花提取物和山茶种子提取物作为活性成分的组合物，以激活AMP活化蛋白激酶（AMPK），抑制脂肪酸合成，促进脂肪酸 氧化和葡萄糖吸收，从而预防和治疗代谢综合征。 构成：用于预防或治疗代谢综合征的组合物含有山茶花提取物，山茶花提取物和山茶种子提取物作为活性成分，重量比为4-12:0.3-4:0.3-4。 该组合物含有山茶叶提取物和山茶花和种子提取物，重量比为4-12：0.2-8。 代谢综合征是葡萄糖苷代谢综合征或脂代谢综合征。 代谢综合征包括肥胖，高脂血症，2型糖尿病，动脉硬化，心肌梗塞和心绞痛中的一种或多种。 组合物是药物组合物。 （参考号）（AA）山茶叶，花和种子提取物的混合物; （BB）山茶花提取物; （CC）山茶籽提取物; （DD）山茶叶提取物
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公开(公告)号：KR1020120136583A
公开(公告)日：2012-12-20
申请号：KR1020110055599
申请日：2011-06-09
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing soybean extract, Biota orientalis extract, linseed extract, or Glycyrrhiza uralensis extract is provided to improve blood circulation and to promote hair growth. CONSTITUTION: A composition for preventing hair loss or promoting hair growth contains soybean extract, Biota orientalis extract, linseed extract, or Glycyrrhiza uralensis extract as an active ingredient. A composition for promoting hair growth contains soybean extract, Biota orientalis extract, linseed extract, or Glycyrrhiza uralensis extract as an active ingredient. The extract is prepared using C1-C5 alcohols. [Reference numerals] (AA) Control group; (BB) Comparative embodiment; (CC) Embodiment 5
Abstract translation: 目的：提供含有大豆提取物，东方alis提取物，亚麻子提取物或甘草提取物的组合物，以改善血液循环和促进毛发生长。 构成：用于防止脱发或促进毛发生长的组合物含有大豆提取物，生物多角体提取物，亚麻子提取物或甘草提取物作为活性成分。 用于促进毛发生长的组合物含有大豆提取物，东方生物提取物，亚麻子提取物或甘草提取物作为活性成分。 使用C1-C5醇制备提取物。 （附图标记）（AA）对照组; （BB）比较实施例; （CC）实施例5
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