Abstract:
본발명은대두추출물및 헤마토코쿠스추출물을포함하는피부주름예방또는개선용조성물에대한것으로보다상세하게는대두추출물과헤마토코쿠스플루비알리스추출물을포함하는피부주름예방또는개선용식품용조성물과화장료조성물에대한것이다. 본발명의조성물은독성이거의없고, 대두추출물과헤마토코쿠스추출물각각에비하여자외선으로유발되는콜라겐분해효소의발현억제와주름방지의효과가탁월하여적은양으로도효과적으로광노화등으로인한주름을개선할수 있다. 따라서본 발명의조성물을다양하게제형화하여주름예방또는개선용기능성식품또는화장품을개발하는데유용하게이용될수 있다.
Abstract:
본 발명은 데하이드로글리아스페린 디(dehydroglyasperin D; DHGA-D)를 유효성분으로 포함하는 것을 특징으로 하는 피부질환 예방 또는 치료용 조성물에 관한 것으로, DHGA-D가 MMP-1과 직접 결합하여, MMP-1의 활성을 감소시키고, S-UV 조사에 의해 증가한 MMP-1의 발현을 억제함이 확인되었다. 또한, S-UV의 조사에 의해 증가한 COX-2의 발현과 p38과 JNK의 인산화를 감소시키는 효과도 확인되었다. 따라서, 본 발명의 DHGA-D는 피부질환 예방 또는 치료용 조성물로 개발되어 사용될 수 있다.
Abstract:
PURPOSE: A pharmaceutical composition containing dehydroglyasperin C is provided to suppress nerve cell injury and apoptosis and to improve cognitive function. CONSTITUTION: A pharmaceutical composition for treating cognitive function reduction contains dehydroglyasperin C of chemical formula 1 as an active ingredient. The cognitive function reduction is caused by stroke, dementia, Alzheimer's disease, Parkinson's disease, Huntington' disease, Pick disease, or Creutzfeldt-Jakob disease. A health functional food for reducing cognitive function reduction contains dehydroglyasperin C of chemical formula 1. The health functional food is a tablet, capsule, pill, or liquid.
Abstract:
PURPOSE: A pharmaceutical composition containing sulforaphane or sulforaphane precursors or derivatives is provided to effectively prevent or treat obesity. CONSTITUTION: A pharmaceutical composition for preventing or treating obesity contains 0.1-50 wt% of sulforaphane of chemical formulas 1-9 or sulforaphane precursors or derivatives as an active ingredient. The concentration of the sulforaphane, precursors, or derivatives is 10 uM-1mM. The pharmaceutical composition is used in a form of plasters, granules, lotions, liniments, lemonades, aromatic waters, powders, syrups, liquids and solutions, aerosols, extracts, elixirs, ointments, fluid extracts, emulsions, suspensions, decoctions, infusions, tablets, suppositories, injections, spirits, cataplasma, capsules, creams, pastes, pills, or soft or hard gelatin capsules.
Abstract:
PURPOSE: A composition containing dehydroglyasperin D(DHGA-D) for preventing or treating cutaneous disorders is provided to suppress MMP-1 expression and reduce p38 and JNK phosphorylation. CONSTITUTION: A composition for preventing or treating cutaneous disorders contains 10uM-1mM of dehydroglyasperin D(DHGA-D) as an active ingredient. The cutaneous disorders include skin aging, dermatitis, or skin cancer. The composition is a pharmaceutical composition. The formulation of the pharmaceutical composition includes plasters, granules, lotions, liniments, lemonades, aromatic waters, powders, syrups, ophthalmic ointments, liquids and solutions, aerosols, extracts, elixirs, ointments, fluid extracts, emulsions, suspensions, decoctions, infusions, pills, or soft or hard gelatin capsules.
Abstract:
PURPOSE: An obesity prevention food composition containing hirsutenone, an obesity treating pharmaceutical composition, and an obesity treating composition for animals are provided to offer an anti-obesity effect of a natural active material. CONSTITUTION: An obesity prevention food composition contains 0.000001-50wt% of hirsutenone. An obesity treating pharmaceutical composition also contains 0.000001-50wt% of hirsutenone, and is selected from the group consisting of plasters, granules, lotions, liniments, aromatic water, powder, syrup, ophthalmic ointments, liquid solutions, aerosol, extracts, elixirs, emulsion, suspension, tablets, injections, and other types of medical agents. An obesity treating composition for animals also contain 0.000001-50wt% of hirsutenone.