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公开(公告)号：KR1020120087732A
公开(公告)日：2012-08-07
申请号：KR1020110009110
申请日：2011-01-28
Applicant: 한국과학기술연구원
CPC classification number: B82Y15/00 , A61K49/186 , A61K49/1866 , G01N33/54353
Abstract: PURPOSE: A bio-imaging nanoparticle is provided to ensure excellent water solubility, target selectivity, and bio affinity and to early diagnose diseases. CONSTITUTION: A bio-imaging nanoparticle contains: a core nanoparticle; a binding layer which contains organic ligand(20), surfactant(14) and a polyoxyalkylene derivative(16) of fatty acid ester and covers the core nanoparticle; and a functional molecule(18). The organic ligand is conjugated on the surface of the core nanoparticle. The surfactant is conjugated on a part of the surface, in which organic ligand is not conjugated. The core nanoparticle contains a core(10) and a shell(12). The functional molecule is a bio affinity molecule, target-oriented molecule, or a conjugate or mixture thereof.
Abstract translation: 目的：提供生物成像纳米颗粒，以确保优异的水溶性，目标选择性和生物亲和力，以及早期诊断疾病。 构成：生物成像纳米颗粒包含：核心纳米颗粒; 包含脂肪酸酯的有机配体（20），表面活性剂（14）和聚氧化烯衍生物（16）并覆盖核心纳米颗粒的结合层; 和功能性分子（18）。 有机配体在芯纳米颗粒的表面上共轭。 表面活性剂在表面的一部分上共轭，其中有机配体不共轭。 核心纳米颗粒含有核（10）和壳（12）。 功能分子是生物亲和分子，靶向分子或其缀合物或混合物。
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公开(公告)号：KR101083006B1
公开(公告)日：2011-11-15
申请号：KR1020090059930
申请日：2009-07-01
Applicant: 한국과학기술연구원
Abstract: 본발명은형광파장이보존되고내구성및 형광세기가증대된나노입자-기공체복합비드및 그제조방법에관한것으로서, 기공체비드와; 상기기공체비드의표면에가까운내부의동심구상에방사상으로정전기적인력에의해결합되어있는나노입자들을포함하고, 상기나노입자는발광나노입자, 또는발광나노입자와이종나노입자가혼합되어있는것이며, 상기이종나노입자는자성나노입자, 금속나노입자및 금속산화물나노입자로이루어진군에서선택되는어느하나또는둘 이상이혼합되어있는것인것을특징으로하는나노입자-기공체복합비드및 그제조방법을제공한다.
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公开(公告)号：KR1020050120498A
公开(公告)日：2005-12-22
申请号：KR1020040045864
申请日：2004-06-19
Applicant: 한국과학기술연구원
CPC classification number: C07F3/06 , B82B3/00 , C07F3/08 , C09K11/06 , C09K2211/18
Abstract: 본 발명은 반도체 나노입자용 단일 유기금속 전구체 및 그 합성방법을 제공한다. 상기 방법은 열분해 온도가 300℃ 이하로 낮으며, 상기 단일 유기금속전구체로부터 얻어지는 반도체 나노입자는 입자의 내부결함이 적어서 양자효율이 높고, 입도균일성이 우수하여 반높이 나비 값이 20 nm 이하의 형광을 낼 수 있다.
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公开(公告)号：KR100502882B1
公开(公告)日：2005-07-25
申请号：KR1020020040175
申请日：2002-07-11
Applicant: 한국과학기술연구원
Inventor： 우경자
IPC: C07F1/08
Abstract: 본 발명은 고온 초전도체 물질의 구성성분 중 하나인 산화 구리 박막을 제조하기 위해 사용되는 신규한 유기 구리 화합물 전구체 및 그의 제조 방법에 관한 것이다. 보다 구체적으로, 본 발명은 리간드로서 헥사플루오로아세틸아세토네이트 두 분자와 t-부틸아민 한 분자를 함께 갖는 신규한 유기 구리 화합물 전구체 및 그의 제조 방법에 관한 것이다. 본 발명에 따른 유기 구리 화합물 전구체는 녹는점이 낮고, 기화성이 우수하며, 기화시 열분해 등의 변화가 없어 잔류물이 남지 않고, 기판 위에 순수한 산화 구리 박막을 형성하며, 대기 및 수분에도 안정하여 취급과 보관이 용이하다.
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公开(公告)号：KR100482278B1
公开(公告)日：2005-04-14
申请号：KR1020020064314
申请日：2002-10-21
Applicant: 한국과학기술연구원
Abstract: 본 발명은 값이 싼 저급의 계면활성제와 용매 내에서 쉽고 간편한 방법으로 저급의 철 펜타카르보닐[Fe(CO)
5 ]을 열분해하고 잔류 산소에 의한 산화반응을 진행시켜 2가와 3가의 혼합 산화철 나노분말을 제조하거나, 이 분말 용액에 공기를 주입시켜 산화 반응이 더욱 진행된 마그헤마이트(γ-Fe
2 O
3 ) 나노분말을 제조함으로써, 산화상태에 관계없이 직경이 20 nm 이하로 균일하고 초상자성을 가지며, 입자 사이에 뭉침이 없어 의료용으로 활용이 적합한 구형 산화철 나노분말의 경제적인 합성법을 제공한다.-
Patent Agency Ranking
公开(公告)号：KR1020040029871A
公开(公告)日：2004-04-08
申请号：KR1020020060309
申请日：2002-10-02
Applicant: 한국과학기술연구원
CPC classification number: B82Y30/00 , C01G49/06 , C01P2002/72 , C01P2004/04 , C01P2004/64 , C01P2006/42 , Y10S977/773 , Y10S977/775 , Y10S977/777 , Y10S977/811
Abstract: PURPOSE: Maghemite (γ-Fe2O3) nanopowder used as ultra high density magnetic recording materials by having superior shape anisotropy and magnetic characteristics, hematite (α-Fe2O3) nanopowder used as precursor or catalyst of the maghemite and nanopowder in which the maghemite and hematite are mixed, and a preparation method of shape anisotropic metal oxide nanopowder are provided. CONSTITUTION: In a method for preparing nano sized metal oxide powder having superior magnetic characteristics, the method comprises the steps of precipitating and separating gel shaped amorphous metal oxide powder by adding protonic scavenger to the reverse micelle solution after forming a reverse micelle solution by adding distilled water, surfactant and solvent to metal salts of trivalence or more; controlling a mole ratio of metal oxide to surfactant by cleaning the gel shaped amorphous metal oxide powder using polar solvent; and crystallizing nano sized metal oxide particles through heating or reflux reaction by dispersing the gel shaped amorphous metal oxide powder into a non-polar solvent having high boiling point.
Abstract translation: 目的：通过具有优异的形状各向异性和磁特性，用作赤铁矿（α-Fe2O3）纳米粉末作为磁赤铁矿和纳米粉末的磁赤铁矿和赤铁矿的前驱体或催化剂，用作超高密度磁记录材料的磁赤铁矿（γ-Fe2O3）纳米粉末 提供了形状各向异性金属氧化物纳米粉末的制备方法。 构成：在制备具有优异磁特性的纳米尺寸金属氧化物粉末的方法中，该方法包括以下步骤：通过加入蒸馏器形成反胶束溶液后，通过向反胶束溶液中加入质子清除剂来沉淀和分离凝胶状无定形金属氧化物粉末 水，表面活性剂和溶剂与三价或更多的金属盐; 通过使用极性溶剂清洗凝胶状无定形金属氧化物粉末来控制金属氧化物与表面活性剂的摩尔比; 并通过将凝胶状无定形金属氧化物粉末分散到具有高沸点的非极性溶剂中，通过加热或回流反应结晶纳米尺寸的金属氧化物颗粒。
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公开(公告)号：KR100367574B1
公开(公告)日：2003-01-15
申请号：KR1019990036896
申请日：1999-09-01
Applicant: 한국과학기술연구원
Abstract: PURPOSE: A chromatography separation method using radially directed electric field is provided, which can control residence time of object material in the radial electric field according to the strength of electric field and relative polarity of an object material, a solvent and a packing material and can increase separation efficiency. Therefore the system can achieve high efficiency and high separation performance and also can be applied to chromatography of industrial scale. CONSTITUTION: The method comprises: i) applying voltage of more than 1V to chromatography column to form an electric field radially 1-10 minutes before charging sample; and ii) controlling residence time of the object material by controlling the strength of electric field. The equipment is characterized by a chromatography column (5), wherein an inside electrode (7) and an outside electrode (8) are installed inside and outside of the column respectively to charge electric field for separating an object material from a solvent and a packing material, the column having a channel with an inlet (11) and an outlet (12) for a coolant or heating media to flow.
Abstract translation: 目的：提供一种利用径向电场的色谱分离方法，该方法可以根据电场强度和目标物质，溶剂和包装材料的相对极性来控制目标物质在径向电场中的停留时间，并且可以 提高分离效率。 因此该系统可以实现高效率和高分离性能，也可以应用于工业规模的色谱。 构成：该方法包括：i）在填充样品之前，向色谱柱施加大于1V的电压以在放电1-10分钟之前形成电场; 和ii）通过控制电场的强度来控制目标材料的停留时间。 该设备的特征在于色谱柱（5），其中内部电极（7）和外部电极（8）分别安装在色谱柱的内部和外部以填充用于从溶剂和填料中分离目标物质的电场 材料，该塔具有带有用于冷却剂或加热介质流动的入口（11）和出口（12）的通道。
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公开(公告)号：KR100296738B1
公开(公告)日：2001-10-27
申请号：KR1019980015784
申请日：1998-05-01
Applicant: 한국과학기술연구원
IPC: C08B37/08
Abstract: PURPOSE: Provided is a process for producing chitosan oligosaccharide from polymer chitosan by hydrolysis using an edible organic acid useful for human bodies, which can be used for food additives and medical supplies. CONSTITUTION: The chitosan oligosaccharide is produced by dissolving the polymer chitosan in a water solution of the edible organic acid and performing the hydrolysis in an autoclave by applying microwave, wherein the edible organic acid is selected from the group consisting of tartaric acid, pyruvic acid, ascorbic acid, citric acid, lactic acid, propionic acid, acetic acid, and a mixture thereof and the concentration of the water solution of the organic acid is 3-8wt.%.
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公开(公告)号：KR1020000050905A
公开(公告)日：2000-08-05
申请号：KR1019990001053
申请日：1999-01-15
Applicant: 한국과학기술연구원 , 에스케이케미칼주식회사
IPC: C07C7/10
Abstract: PURPOSE: A method for separating 2,6-dimethylnaphthalene with high purity is provided which solves the problem of loss of 2,6-dimethylnaphthalene and economical efficiency due to addition of the pre-treatment process and easily obtains the 2,6-dimethylnaphthalene with high purity. CONSTITUTION: A method comprises steps of: (i) selectively separating the mixture of dimethylnaphthalene isomer containing 2,6-dimethylnaphthalene from naphthalene mixture containing dimethylnaphthalene isomers by fractional distillation or recrystallization; and (ii) separating the 2,6-dimethylnaphthalene from the mixture of dimethylnaphthalene isomer containing 2,6-dimethylnaphthalene by pressure crystallization using solvent.
Abstract translation: 目的：提供一种分离高纯度2,6-二甲基萘的方法，其解决了由于加入预处理过程而导致2,6-二甲基萘损失和经济性的问题，并且容易地获得2,6-二甲基萘与 高纯度 构成：一种方法包括以下步骤：（i）通过分馏或重结晶从包含二甲基萘异构体的萘混合物中选择性地分离含有2,6-二甲基萘的二甲基萘异构体的混合物; 和（ii）通过使用溶剂的压力结晶从2,6-二甲基萘的二甲基萘异构体的混合物中分离出2,6-二甲基萘。
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