公开(公告)号：WO1995034341A1

公开(公告)日：1995-12-21

申请号：PCT/US1995005998

申请日：1995-05-12

Applicant: C.R. BARD, INC.

Inventor： C.R. BARD, INC. ,  PATTERSON, Frank ,  ZHANG, John ,  PURTELL, George ,  CULHANE, James

IPC: A61M39/00

CPC classification number: A61M25/0662 ,  A61M39/0606 ,  A61M2039/062 ,  A61M2039/0633 ,  A61M2039/064 ,  A61M2039/0653 ,  A61M2039/066

Abstract: An improved self-sealing gasket provides hemostasis while reducing the force required to move a catheter or guidewire positioned within the gasket. Slits formed on one surface of the gasket intersect with a central aperture formed on the opposite face of the gasket. An annular ring formed on the gasket assists in retaining the gasket within a catheter introducer. An annular shelf may be provided distally of the gasket to prevent dislodgement of the gasket if an instrument is inserted into the introducer off axially.

Abstract translation: 改进的自密封衬垫提供止血，同时减少移动位于垫圈内的导管或导丝所需的力。 在垫圈的一个表面上形成的狭缝与形成在垫片的相对面上的中心孔相交。 形成在垫圈上的环形圈有助于将垫圈保持在导管引导器内。 如果将仪器从轴向插入引导器中，则可以在垫片的远侧设置环形搁架以防止垫圈的移位。

公开(公告)号：WO1995033511A1

公开(公告)日：1995-12-14

申请号：PCT/US1995007266

申请日：1995-06-07

Applicant: C.R. BARD, INC.

Inventor： C.R. BARD, INC. ,  LEE, Clarence, C.

IPC: A61M31/00

CPC classification number: A61K9/0024 ,  A61K9/0034 ,  A61K9/0092 ,  A61M31/002

Abstract: The present invention is an implantable device that is capable of delivering a therapeutic agent to a tissue or organ over a long period of time. The implantable device is especially suited for treating tissues and organs that are comprised of smooth muscle. The implantable device can deliver either a single therapeutic agent or a plurality of therapeutic agents to the tissue or organ at zero order kinetics.

Abstract translation: 本发明是能够长时间将治疗剂递送至组织或器官的可植入装置。 可植入装置特别适用于治疗由平滑肌组成的组织和器官。 可植入装置可以以零级动力学将单一治疗剂或多种治疗剂递送至组织或器官。

公开(公告)号：WO1995017223A1

公开(公告)日：1995-06-29

申请号：PCT/US1994014604

申请日：1994-12-21

Applicant: C.R. BARD, INC.

Inventor： C.R. BARD, INC. ,  FAGAN, John, R. ,  KLING, Jeffrey

IPC: A61M25/10

CPC classification number: A61M25/1002 ,  A61M25/104 ,  A61M2025/1086

Abstract: A dilatation balloon having at least one helical groove disposed in at least a portion of the dilating surface of the dilatation balloon is mounted on the distal end of a catheter shaft. Multiple helical grooves may be provided in the dilatation balloon extending parallel to each other or opposite to each other in the dilating surface. Each helical groove has a pitch, width and depth. According to one aspect of the invention, the pitch, width and depth of the helical groove, as well as the number of grooves, are selected to allow perfusion of blood past the dilatation catheter when the dilatation balloon is inflated in a blood vessel. According to another aspect of the invention, the pitch, width, and depth of the helical groove, as well as the number of grooves, are selected so that the dilatation balloon conforms to a tortuous blood vessel and does not straighten the blood vessel during dilation. According to another aspect of the invention, the pitch, width, and depth of the helical groove, as well as the number of grooves, are selected to control the diametrical compliance of the dilatation balloon. The pitch, width, and depth of the helical groove may be selected to provide both conformance to the shape of tortuous blood vessels and diametrical compliance. The helical groove also permits the dilatation balloon to deflate without "winging", i.e., forming undesirable flat folds that extend outward from the rest of the catheter.

Abstract translation: 具有设置在扩张球囊的扩张表面的至少一部分中的至少一个螺旋槽的扩张球囊安装在导管轴的远端。 可以在膨胀气囊中设置多个螺旋槽，该膨胀气囊在扩张表面中彼此平行延伸或彼此相对延伸。 每个螺旋槽具有间距，宽度和深度。 根据本发明的一个方面，选择螺旋槽的间距，宽度和深度以及凹槽的数量，以便当膨胀球囊在血管中膨胀时允许血液经过扩张导管灌注。 根据本发明的另一方面，选择螺旋槽的间距，宽度和深度以及凹槽的数量，使得膨胀球囊符合曲折的血管，并且在扩张期间不使血管伸直 。 根据本发明的另一方面，选择螺旋槽的间距，宽度和深度以及凹槽的数量以控制膨胀气囊的直径依从性。 可以选择螺旋槽的螺距，宽度和深度以提供符合曲折血管形状和直径依从性。 螺旋槽还允许扩张气囊在没有“翼”的情况下放气，即形成从导管的其余部分向外延伸的不期望的平折。

公开(公告)号：WO1994004601A1

公开(公告)日：1994-03-03

申请号：PCT/US1993007761

申请日：1993-08-20

Applicant: C.R. BARD, INC.

Inventor： C.R. BARD, INC. ,  OSTAPCHENKO, George, Joseph ,  GODAIRE, Raymond, Edmund

IPC: C08J07/00

CPC classification number: C08J7/02 ,  A61L29/06 ,  C08J7/12 ,  C08J2367/02 ,  C08L67/02

Abstract: There is disclosed herein a process for preparing an oriented polyethylene terephthalate article, by (a) surface treating the article to obtain good adhesive bonding by increasing the concentration of surface polar groups, and then (b) contacting the treated surface with suitable solvent that preserves the good adhesive bonding characteristics but removes undesirable blocking characteristics.

Abstract translation: 本文公开了一种制备取向的聚对苯二甲酸乙二醇酯制品的方法，其通过（a）通过增加表面极性基团的浓度来表面处理制品以获得良好的粘合剂粘合，然后（b）使经处理的表面与合适的溶剂接触， 良好的粘合特性，但消除不希望的阻塞特性。

公开(公告)号：WO1993017635A1

公开(公告)日：1993-09-16

申请号：PCT/US1993002006

申请日：1993-03-04

Applicant: C.R. BARD, INC.

Inventor： C.R. BARD, INC. ,  LICHTENSTEIN, Irving, L. ,  TURNQUIST, Carl, R.

IPC: A61F02/00

CPC classification number: A61F2/0063 ,  A61B2090/0816 ,  A61F2002/0068 ,  A61F2210/0004 ,  A61F2250/0051

Abstract: A composite prosthesis (10) and method for limiting the incidence of postoperative adhesions. The composite (10) includes a mesh fabric (12) and a barrier (14) which prevents exposure of the mesh fabric (12) to areas of potential adhesion. The interstices of the mesh fabric (12) are infiltrated by tissue which secures the prosthesis in place. The composite is positioned with the barrier (14) relative to the region of potential adhesion, such as the abdominal viscera.

Abstract translation: 复合假体（10）和限制术后粘连发生率的方法。 复合材料（10）包括网眼织物（12）和防止网眼织物（12）暴露于潜在粘附区域的阻挡层（14）。 网状织物（12）的间隙被固定在适当位置的组织渗透。 复合物相对于潜在粘附区域（例如腹部内脏）与屏障（14）定位。

公开(公告)号：WO1992007623A1

公开(公告)日：1992-05-14

申请号：PCT/US1991007474

申请日：1991-10-10

Applicant: C.R. BARD, INC.

Inventor： C.R. BARD, INC. ,  SINOFSKY, Edward ,  ANDRUS, W., Scott ,  MADDEN, Michael

IPC: A61N05/06

CPC classification number: A61B8/12 ,  A61B5/02007 ,  A61B8/0833 ,  A61B8/0858 ,  A61B8/445 ,  A61B8/4483 ,  A61B18/245 ,  A61B2017/00106

Abstract: Apparatus (14) for use in removing atherosclerotic plaque (10) deposits in a blood vessel (12) comprises a high power laser (42), an elongated, flexible catheter (18) adapted to be inserted into and advanced through the blood vessel (12), a plurality of circumferentially arrayed optical fibers (22) extending axially through the catheter, and an ultrasonic transducer (26) at the distal end of the catheter for transmitting acoustical energy toward a selected area of the inner surface of a blood vessel (12) in response to laser energy coupled through any one of the optical fibers (22) and impinging upon the transducer (26). A detector (32, 34, 36) proximal of the ultrasonic transducer is responsive to ultrasonic energy reflected from the blood vessel (12) and produces a signal indicative of the tissue interfaces of the blood vessel. Laser energy can be transmitted from the high power laser (42) through the same optical fiber used for the diagnostic procedure to ablate plaque in the blood vessel.

公开(公告)号：WO1986004247A1

公开(公告)日：1986-07-31

申请号：PCT/US1986000133

申请日：1986-01-21

Applicant: C.R. BARD, INC.

Inventor： C.R. BARD, INC. ,  FELIX, Augustus ,  UHOCH, John

IPC: A61N01/30

CPC classification number: A61M1/0064 ,  A61M1/0045 ,  Y10S604/902

Abstract: A handpiece (10) for a surgical irrigation and suction device includes a trigger operated valving mechanism which controls the release of irrigation fluid. The valving mechanism includes a flexible tube (38) which defines a portion of the irrigation conduit (40). The valving mechanism further includes a hook and rib arrangement (84, 86, 88) in which the flexible tube (38) can be drawn into a V-shaped kinked configuration which closes off flow through the tube. The spring (90) is connected to a trigger (24) which, when squeezed, shifts positions of the spring (90) to release the kink and permit liquid flow. An irrigation wand (16) may be provided with a special nozzle (108) which directs a plurality of streams of irrigation fluid in a single plane spray pattern. A retainer clip (74) may be provided to prevent inadvertent separation of the wands (16, 18).