公开(公告)号：SE8306994L

公开(公告)日：1983-12-16

申请号：SE8306994

申请日：1983-12-16

Applicant: HOECHST AG

Inventor： DURCKHEIMER W ,  BORMANN D ,  EHLERS E ,  SCHRINNER E ,  HAYMES R

IPC: A61K31/397 ,  A61K31/435 ,  A61K31/505 ,  A61K31/535 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  B25J15/08 ,  C07D205/08 ,  C07D277/20 ,  C07D277/40 ,  C07D277/42 ,  C07D277/50 ,  C07D463/00 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04 ,  C07D501/20 ,  C07D501/24 ,  C07D501/36 ,  C07D505/00 ,  C07D519/06 ,  C07F9/6561 ,  C07D501/48

Abstract: Cephem derivatives of the general formula in which the R2O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.

公开(公告)号：NZ189266A

公开(公告)日：1981-12-15

申请号：NZ18926678

申请日：1978-12-21

Applicant: HOECHST AG

Inventor： BLUMBACH J ,  DUERCKHEIMER W ,  SCHRINNER E

IPC: C07D501/06 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/46 ,  C07D501/34

Abstract: Cephalosporin derivatives of the formula I processes for their manufacture and their use for combating bacterial infections.

公开(公告)号：DK578978A

公开(公告)日：1979-06-25

申请号：DK578978

申请日：1978-12-22

Applicant: HOECHST AG

Inventor： BLUMBACH J ,  DUERCKHEIMER W ,  SCHRINNER E

IPC: C07D501/06 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/46 ,  C07D501/34 ,  C07D

Abstract: Cephalosporin derivatives of the formula I processes for their manufacture and their use for combating bacterial infections.

公开(公告)号：ZA7802168B

公开(公告)日：1979-03-28

申请号：ZA7802168

申请日：1978-04-14

Applicant: HOECHST AG

Inventor： SCHRINNER E ,  SELIGER H ,  DUERCKHEIMER W ,  EHLERS E

IPC: A61K20060101 ,  A61K31/545 ,  A61K31/546 ,  A61K31/675 ,  A61K31/695 ,  A61P31/04 ,  B23K1/18 ,  B23Q5/033 ,  C07D20060101 ,  C07D277/20 ,  C07D277/40 ,  C07D501/00 ,  C07D501/20 ,  C07D501/24 ,  C07D501/34 ,  C07D501/36 ,  C07D501/46 ,  C07D501/59 ,  C07D501/60 ,  C07D519/06

CPC classification number: C07D501/20 ,  Y02P20/55

公开(公告)号：ZA7801433B

公开(公告)日：1979-02-28

申请号：ZA7801433

申请日：1978-03-10

Applicant: HOECHST AG

Inventor： SCHRINNER E ,  BORMANN D ,  KNABE B ,  WORM M

IPC: A61K31/44 ,  A61K31/535 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/38 ,  C07D277/40 ,  C07D463/00 ,  C07D501/20 ,  C07D505/00 ,  A61K31/00

CPC classification number: C07D277/20 ,  C07D277/587

公开(公告)号：SE7803660A

公开(公告)日：1978-10-03

申请号：SE7803660

申请日：1978-03-31

Applicant: HOECHST AG

Inventor： DURCKHEIMER W ,  BORMANN D ,  EHLERS E ,  SCHRINNER E ,  HAYMES R

IPC: A61K31/397 ,  A61K31/435 ,  A61K31/505 ,  A61K31/535 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  B25J15/08 ,  C07D205/08 ,  C07D277/20 ,  C07D277/40 ,  C07D277/42 ,  C07D277/50 ,  C07D463/00 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04 ,  C07D501/20 ,  C07D501/24 ,  C07D501/36 ,  C07D505/00 ,  C07D519/06 ,  C07F9/6561 ,  C07D487/02 ,  C07D501/34

CPC classification number: C07D277/20 ,  A61K31/435 ,  A61K31/505 ,  A61K31/535 ,  A61K31/545 ,  C07D277/40 ,  C07D277/42 ,  C07D277/50 ,  C07D277/587 ,  C07D463/22 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04 ,  C07D505/00

公开(公告)号：SE7802853L

公开(公告)日：1978-09-13

申请号：SE7802853

申请日：1978-03-13

Applicant: HOECHST AG

Inventor： BORMANN D ,  KNABE B ,  SCHRINNER E ,  WORM M

IPC: A61K31/44 ,  A61K31/535 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/38 ,  C07D277/40 ,  C07D463/00 ,  C07D501/20 ,  C07D505/00 ,  C07D501/24 ,  C07D498/04

Abstract: Cephem derivatives of the formula in which R1 denotes hydrogen or low-molecular alkoxy, R2 denotes hydrogen, optionally substituted alkyl, phthalide or a cation, X denotes sulfur, oxygen or CH2 and A denotes hydrogen, alkoxy, halogen or a group -CH2Y, in which Y represents hydrogen, acyloxy, alkoxy, optionally substituted carbamoyloxy or a group -SR3, in which R3 can represent acyl, alkyl or an optionally substituted 5-membered or 6-membered heterocyclic structure are disclosed as valuable antibiotics which are well suited for combating Gram-positive and in particular Gram-negative infections and also have an unexpectedly good action against penicillinase-forming staphylococci.

公开(公告)号：SE390538B

公开(公告)日：1976-12-27

申请号：SE491272

申请日：1972-04-14

Applicant: HOECHST AG

Inventor： SCHORR M ,  SCHRINNER E

IPC: A61K20060101 ,  A61K31/43 ,  C07D20060101 ,  C07D499/12 ,  C07D499/34 ,  C07D499/48 ,  C07D501/06 ,  C07D501/26 ,  C07D501/32 ,  C07D501/60

Abstract: Acylaminocephalosporanic acids of the formula I wherein R1, R2 and R3 each represents hydrogen or lower alkyl radicals in which case R1 and R2 may also form together an optionally substituted alkylene radical, A represents an optionally substituted phenylene or thienyl radical, and X represents an oxygen atom or a single bond, the physiologically tolerable salts thereof, pharmaceutical preparations effective against bacterial infections containing these compounds, and a process for the manufacture.

公开(公告)号：ZA7407594B

公开(公告)日：1975-12-31

申请号：ZA7407594

申请日：1974-11-28

Applicant: HOECHST AG

Inventor： SCHRINNER E ,  WORM M ,  BORMANN D ,  KNABE B

IPC: A61K20060101 ,  A61K31/43 ,  A61K31/545 ,  C01D20060101 ,  C07D20060101 ,  C07D501/04 ,  C07D501/06 ,  C07D501/20 ,  C07D501/24 ,  C07D501/36 ,  C07D501/40 ,  C07D501/42 ,  C07D501/46 ,  C07D501/48 ,  C07D501/56 ,  C07D501/60 ,  C07D519/00 ,  C07D521/00 ,  C07D

CPC classification number: C07D501/36 ,  Y02P20/55

公开(公告)号：ZA747042B

公开(公告)日：1975-11-26

申请号：ZA747042

申请日：1974-11-01

Applicant: HOECHST AG

Inventor： SCHRINNER E ,  GERHARDS H ,  HARTUNG H ,  DUERCKHEIMER W

IPC: C07D295/14 ,  A61K20060101 ,  A61K31/65 ,  C07C20060101 ,  C07C67/00 ,  C07C231/00 ,  C07C231/08 ,  C07C237/26 ,  C07D20060101 ,  C07D207/16 ,  C07D211/34 ,  C07D211/62 ,  C07D227/00 ,  C07D235/12 ,  C07D269/00 ,  C07D295/02 ,  C07D295/04 ,  C07C ,  C07D

Abstract: 2-Carboxamido-substituted tetracyclines of the general formula A PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THESE COMPOUNDS.