公开(公告)号：NO169133B

公开(公告)日：1992-02-03

申请号：NO872015

申请日：1987-05-14

Applicant: HOECHST AG

Inventor： BADER HUBERT ,  RUEPPEL DIETHER ,  WALCH AXEL ,  MAGERSTAEDT MICHAEL

IPC: A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22 ,  A61K47/00 ,  A61K47/34 ,  C08G69/02 ,  C08G69/10 ,  C08G69/44 ,  C08G69/36

Abstract: Polyamides in which amino acids are incorporated in the polymer backbone via two amino or carboxyl groups and which carry in the alpha -position to the amide structure a functional group which is responsible for degradation and active compound release are highly suitable for the preparation of biologically degradable active compound depot preparations having controlled release of the active compound.

公开(公告)号：CA2035279A1

公开(公告)日：1991-08-01

申请号：CA2035279

申请日：1991-01-30

Applicant: HOECHST AG

Inventor： KRONE VOLKER ,  WALCH AXEL

IPC: A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/52 ,  A61K9/58 ,  A61K47/34 ,  C07D207/416 ,  C07D211/76 ,  C08G73/10 ,  C08G73/14 ,  C08G69/10 ,  A61K9/22

Abstract: - 1 - HOE 90/F 033 of the disclosure "Biologically degradable polymers, process for their preparation and use thereof for depot preparations having controlled delivery of active compound" The invention relates to biologically degradable polymers, in particular polyaminodicarboxylic acid-co-anhydroaminodicarboxylic acid derivatives, to a process for their preparation and to the use thereof for depot preparations having controlled delivery of active compound.

公开(公告)号：IE903404A1

公开(公告)日：1991-04-10

申请号：IE340490

申请日：1990-09-20

Applicant: HOECHST AG

Inventor： BUCHHOLZ RAINER ,  GIANI CARLO ,  FRICKE ULRICH ,  RUEPPEL DIETER ,  WALCH AXEL ,  BAYER THOMAS ,  KURRLE ROLAND ,  KRAUSE DIETER ,  LANG WIEGAND ,  REICHE ASMUS

IPC: C12N11/04 ,  C12N5/00 ,  C12N5/04 ,  C12N5/06

Abstract: The invention relates to a process for the culture of cells which are entrapped in hollow microbeads and are densely packed in a fixed bed and are supplied with nutrients discontinuously or continuously in a vessel by the medium flow. The suitable hollow microbeads have a membrane composed of a polysaccharide gel or of a polyelectrolyte.

公开(公告)号：ES2017955B3

公开(公告)日：1991-03-16

申请号：ES87106203

申请日：1987-04-29

Applicant: HOECHST AG

Inventor： BADER HUBERT ,  RUPPEL DIETHER ,  WALCH AXEL

IPC: A61K9/16 ,  A61K9/50 ,  B01J13/02 ,  B01J13/08 ,  C12N11/04

公开(公告)号：NO872015A

公开(公告)日：1987-11-16

申请号：NO872015

申请日：1987-05-14

Applicant: HOECHST AG

Inventor： BADER HUBERT ,  RUEPPEL DIETHER ,  WALCH AXEL ,  MAGERSTAEDT MICHAEL

IPC: A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22 ,  A61K47/00 ,  A61K47/34 ,  C08G69/02 ,  C08G69/10 ,  C08G69/44 ,  C08G69/00 ,  A61L15/03 ,  A61L27/00

CPC classification number: C08G69/44 ,  A61K9/1641 ,  A61K9/2045 ,  C08G69/02 ,  C08G69/10

公开(公告)号：CA1225806A

公开(公告)日：1987-08-25

申请号：CA417365

申请日：1982-12-09

Applicant: HOECHST AG

Inventor： WALCH AXEL ,  WILDHARDT JUERGEN ,  BEISSEL DIETER

IPC: C08L39/00 ,  B01D67/00 ,  B01D71/44 ,  B01D71/56 ,  B01D71/68 ,  C08J9/28 ,  C08L39/06 ,  C08L77/00 ,  C08L81/00

Abstract: Disclosed are asymmetrical macroporous membranes based on a synthetic polymer comprising a polymeric mixture of 5 to 70% by weight polyvinylpyrrolidone having a molecular weight ? 100,000 Dalton and 95 to 30% by weight of a polymer selected from a group consisting of a polysulfone, a polyether sulfone and an aromatic or araliphatic polyamide, each of the percentages by weight being relative to the total weight of the polymeric mixture. The membrane has a water absorbency of at least 11% by weight of water, relative to its total weight, at 100% relative humidity and 25.degree.C. Also disclosed is a process for preparation of the membranes.

公开(公告)号：NO872015D0

公开(公告)日：1987-05-14

申请号：NO872015

申请日：1987-05-14

Applicant: HOECHST AG

Inventor： BADER HUBERT ,  RUEPPEL DIETHER ,  WALCH AXEL ,  MAGERSTAEDT MICHAEL

IPC: A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22 ,  A61K47/00 ,  A61K47/34 ,  C08G69/02 ,  C08G69/10 ,  C08G69/44 ,  C08G69/00 ,  A61L15/03 ,  A61L27/00

Abstract: Polyamides in which amino acids are incorporated in the polymer backbone via two amino or carboxyl groups and which carry in the alpha -position to the amide structure a functional group which is responsible for degradation and active compound release are highly suitable for the preparation of biologically degradable active compound depot preparations having controlled release of the active compound.

公开(公告)号：DK223887D0

公开(公告)日：1987-05-01

申请号：DK223887

申请日：1987-05-01

Applicant: HOECHST AG

Inventor： BADER HUBERT ,  RUEPPEL DIETER ,  WALCH AXEL

IPC: A61K9/16 ,  A61K9/50 ,  B01J13/02 ,  B01J13/08 ,  C12N11/04 ,  C12N11/10

公开(公告)号：AU9147482A

公开(公告)日：1983-06-23

申请号：AU9147482

申请日：1982-12-14

Applicant: HOECHST AG

Inventor： WALCH AXEL ,  WILDHARDT JUERGEN ,  BEISSEL DIETER

IPC: C08L39/00 ,  B01D67/00 ,  B01D71/44 ,  B01D71/56 ,  B01D71/68 ,  C08J9/28 ,  C08L39/06 ,  C08L77/00 ,  C08L81/00 ,  B01D13/04

Abstract: Disclosed are asymmetrical macroporous membranes based on a synthetic polymer comprising a polymeric mixture of 5 to 70% by weight polyvinylpyrrolidone having a molecular weight >/=100,000 Dalton and 95 to 30% by weight of a polymer selected from a group consisting of a polysulfone, a polyether sulfone and an aromatic or araliphatic polyamide, each of the percentages by weight being relative to the total weight of the polymeric mixture. The membrane has a water absorbency of at least 11% by weight of water, relative to its total weight, at 100% relative humidity and 25 DEG C. Also disclosed is a process for preparation of the membranes.

公开(公告)号：NO824236A

公开(公告)日：1983-06-20

申请号：NO824236

申请日：1982-12-16

Applicant: HOECHST AG

Inventor： WALCH AXEL ,  WILDHARDT JUERGEN ,  BEISSEL DIETER

IPC: C08L39/00 ,  B01D67/00 ,  B01D71/44 ,  B01D71/56 ,  B01D71/68 ,  C08J9/28 ,  C08L39/06 ,  C08L77/00 ,  C08L81/00 ,  B01D ,  A61M

CPC classification number: B01D67/0011 ,  B01D69/02 ,  B01D71/44 ,  B01D71/56 ,  B01D71/68 ,  B01D2323/12 ,  B01D2325/022 ,  B01D2325/34 ,  B01D2325/36 ,  C08L39/06 ,  C08L2666/14