公开(公告)号：WO2007004195A2

公开(公告)日：2007-01-11

申请号：PCT/IB2006052247

申请日：2006-07-04

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  KOEHLER THOMAS ,  FORTHMANN PETER

Inventor： KOEHLER THOMAS ,  FORTHMANN PETER

CPC classification number: G06T11/006 ,  A61B6/027 ,  G06T2211/432

Abstract: CT scanners have a certain scan-field-of-view defined by the fan-angle of the system. According to an exemplary embodiment of the present invention, object points outside the scan-field-of-view may be reconstructed on the basis of a system of linear equations which may be solved iteratively and with reasonable effort. Therefore, explicit regularization techniques may be applied to recover the unknown object function.

Abstract translation: CT扫描仪具有由系统的扇角定义的特定扫描视场。 根据本发明的示例性实施例，可以基于线性方程式的系统重建扫描视野外的物点，其可以以合理的努力迭代地求解。 因此，可以应用明确的正则化技术来恢复未知对象的功能。

公开(公告)号：WO2006067671A3

公开(公告)日：2006-09-14

申请号：PCT/IB2005054198

申请日：2005-12-13

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  FORTHMANN PETER ,  KOEHLER THOMAS ,  MANZKE ROBERT ,  GRASS MICHAEL ,  ZIEGLER ANDY

Inventor： FORTHMANN PETER ,  KOEHLER THOMAS ,  MANZKE ROBERT ,  GRASS MICHAEL ,  ZIEGLER ANDY

IPC: A61B6/00 ,  A61B6/03

CPC classification number: A61B6/541 ,  A61B6/027 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/503

Abstract: A method of recording images of the heart in computed tomography is provided in which, in order to prevent movement artifacts, the images are reconstructed on the basis of similar movement states of the heart and different radiation intensities are used for different movement states. During recording operation low-resolution images are continually reconstructed from the recorded data. The movement state of the heart is determined from the low- resolution images, preferably by comparing successive images. During the desired heart phase with little heart movement the power of the X-ray tube is increased. A high-resolution reconstruÌtion is carried out retrospectively from data recorded with a high radiation intensity in similar movement states with little heart movement. Also disclosed are a CT apparatus and a computer program for carrying out the method.

Abstract translation: 提供了一种在计算机断层摄影中记录心脏图像的方法，其中为了防止运动伪像，基于心脏的相似运动状态重建图像，并且不同的辐射强度用于不同的运动状态。 在记录操作期间，从记录的数据中连续重建低分辨率图像。 优选地，通过比较连续图像，从低分辨率图像确定心脏的移动状态。 在期望的心脏移动期间，X射线管的功率增加。 从具有较小的心脏运动的相似运动状态下以高辐射强度记录的数据追溯地进行高分辨率重建。 还公开了一种用于执行该方法的CT装置和计算机程序。

公开(公告)号：WO2005023114A8

公开(公告)日：2006-06-29

申请号：PCT/IB2004051523

申请日：2004-08-23

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  BONTUS CLAAS ,  KOEHLER THOMAS ,  GRASS MICHAEL

Inventor： BONTUS CLAAS ,  KOEHLER THOMAS ,  GRASS MICHAEL

IPC: A61B6/00 ,  A61B6/03 ,  G06T11/00

CPC classification number: A61B6/5217 ,  A61B6/027 ,  A61B6/032 ,  A61B6/4028 ,  A61B6/5264 ,  A61B6/527 ,  A61B6/541 ,  G06T11/005 ,  G06T11/006 ,  G06T2211/412

Abstract: The invention relates to a computer tomography method in which an examination area is passed through by a cone-shaped bundle of rays. The bundle of rays comes from a radiation source location which moves around the examination area on an overall trajectory. The overall trajectory consists of a first, closed partial trajectory, at least one second, closed partial trajectory and at least one third partial trajectory which connects the first and the at least one second partial trajectories to one another. Measured values which depend on the intensity in the bundle of rays on the other side of the examination area are acquired by means of a detector unit while the radiation source location is moving on the overall trajectory, and a CT image of the examination area is reconstructed from these measured values.

Abstract translation: 本发明涉及一种计算机断层摄影方法，其中检查区域通过锥形束的光束通过。 一束光线来自在总体轨迹上围绕检查区域移动的辐射源位置。 整个轨迹由第一，闭合的部分轨迹，至少一个第二，闭合的部分轨迹和至少一个将第一和第二部分轨迹相互连接的第三部分轨迹组成。 在辐射源位置在整个轨迹上移动的同时，通过检测器单元获取取决于检查区另一侧的光线束强度的测量值，并且重建检查区域的CT图像 从这些测量值。

公开(公告)号：WO2012104770A2

公开(公告)日：2012-08-09

申请号：PCT/IB2012050418

申请日：2012-01-30

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  ROESSL EWALD ,  KOEHLER THOMAS

Inventor： ROESSL EWALD ,  KOEHLER THOMAS

IPC: G21K1/06

CPC classification number: G21K1/065 ,  G01N23/04 ,  G21K1/06 ,  G21K2207/005

Abstract: The present invention relates to X-ray differential phase-contrast imaging, in particular to a deflection device for X-ray differential phase-contrast imaging. In order to provide differential phase-contrast imaging with improved dose efficiency, a deflection device (28) for X-ray differential phase-contrast imaging is provided, comprising a deflection structure (41) with a first plurality (44) of first areas (46), and a second plurality (48) of second areas (50). The first areas are provided to change the phase and/or amplitude of an X- ray radiation; and wherein the second areas are X-ray transparent. The first and second areas are arranged periodically such that, in the cross section, the deflection structure is provided with a profile arranged such that the second areas are provided in form of groove-like recesses (54) formed between first areas provided as projections (56). The adjacent projections form respective side surfaces (58)partly enclosing the respective recess arranged in between. The side surfaces of each recess have a varying distance (60) across the depth (62) of the recess.

Abstract translation: X射线差分相位对比成像技术领域本发明涉及X射线差分相位对比成像，尤其涉及一种用于X射线差分相位对比成像的偏转装置。 为了提供具有改善的剂量效率的差分相衬成像，提供了用于X射线差分相衬成像的偏转装置（28），其包括具有第一多个（44）第一区域（44）的偏转结构（41） 46）和第二多个（48）第二区域（50）。 提供第一区域以改变X射线辐射的相位和/或振幅; 并且其中第二区域是X射线透明的。 第一区域和第二区域周期性地布置，使得在该横截面中，偏转结构设置有轮廓，该轮廓布置成使得第二区域以形成在作为凸起设置的第一区域之间的凹槽状凹部（54） 56）。 相邻的凸出部分形成相应的侧表面（58），部分地包围设置在其间的相应凹槽。 每个凹槽的侧表面在凹槽的深度（62）上具有变化的距离（60）。

公开(公告)号：WO2010041193A2

公开(公告)日：2010-04-15

申请号：PCT/IB2009054353

申请日：2009-10-05

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  FORTHMANN PETER ,  KOEHLER THOMAS ,  VAN STEVENDAAL UDO ,  BERTRAM MATTHIAS ,  WIESNER STEFFEN ,  SCHRETTER COLAS

Inventor： FORTHMANN PETER ,  KOEHLER THOMAS ,  VAN STEVENDAAL UDO ,  BERTRAM MATTHIAS ,  WIESNER STEFFEN ,  SCHRETTER COLAS

IPC: G01N23/04 ,  A61B6/03

CPC classification number: A61B6/032 ,  A61B5/107 ,  A61B6/027

Abstract: A method and apparatus are provided to improve CT image acquisition using a displaced acquisition geometry. A CT apparatus may be used having a source (102) and a detector (104) transversely displaced from a center (114) of a field of view (118) during acquisition of the projection data. The amount of transverse displacement may be determined based on the size of the object (108). The source and the detector may be adjusted to vary the size of the transverse field of view. The first data set acquired by the detector may be reconstructed and used to simulate missing projection data that could not be acquired by the detector at each projection angle. The measured projection data and the simulated projection data may be used to obtain a second data set. The second data set may be compared to the first data set to produce a corrected data set.

Abstract translation: 提供了一种方法和装置，用于改善使用位移采集几何形状的CT图像采集。 可以使用CT装置，在获取投影数据期间具有从视场（118）的中心（114）横向移位的源（102）和检测器（104）。 可以基于物体（108）的尺寸来确定横向位移量。 源和检测器可以被调节以改变横向视场的大小。 由检测器获取的第一数据集可以被重构并用于模拟在每个投影角度不能由检测器获取的丢失的投影数据。 所测量的投影数据和模拟投影数据可用于获得第二数据集。 可以将第二数据集与第一数据集进行比较以产生校正数据集。

公开(公告)号：WO2009034508A3

公开(公告)日：2009-06-18

申请号：PCT/IB2008053611

申请日：2008-09-05

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  KOEHLER THOMAS ,  WIEMKER RAFAEL

Inventor： KOEHLER THOMAS ,  WIEMKER RAFAEL

IPC: G06T7/00

CPC classification number: G06T7/0012 ,  G06T11/008 ,  G06T2207/10072 ,  G06T2207/30064

Abstract: The invention relates to a method and an image processing device (10) for the evaluation of image raw-data of a body region generated with an imaging device like a CT scanner (30). From the image raw-data, a first image (ICAD) is reconstructed with a reconstruction module (12) according to reconstruction parameters (p) set optimally by a computer aided detection and/or diagnosis (CAD) module (13). This module can then evaluate an image (ICAD) that was reconstructed optimally according to its own requirements, for example with respect to image size and/or resolution, to find features of interest.

Abstract translation: 本发明涉及一种用于评估由CT扫描仪（30）等成像装置生成的身体部位的图像原始数据的方法和图像处理装置（10）。 根据图像原始数据，根据通过计算机辅助检测和/或诊断（CAD）模块（13）最优地设置的重建参数（p），利用重建模块（12）重建第一图像（ICAD）。 然后，该模块可以评估根据其自身要求（例如关于图像大小和/或分辨率）最优重建的图像（ICAD），以找到感兴趣的特征。

公开(公告)号：WO2008075267A3

公开(公告)日：2008-08-14

申请号：PCT/IB2007055083

申请日：2007-12-13

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  SHECHTER GILAD ,  GLASBERG SHMUEL ,  VAN STEVENDAAL UDO ,  FORTHMANN PETER ,  KOEHLER THOMAS ,  BONTUS CLAAS

Inventor： SHECHTER GILAD ,  GLASBERG SHMUEL ,  VAN STEVENDAAL UDO ,  FORTHMANN PETER ,  KOEHLER THOMAS ,  BONTUS CLAAS

IPC: A61B6/06

CPC classification number: A61B6/06

Abstract: An imaging device (100,200) for imaging a volume of interest (5,45) of a subject (4,44) comprises a radiation source (1) for emitting radiation (6), which is arranged for rotational movement around an axis (8) of the subject (4,44), a collimator (3) for collimating the radiation (6) at least in the axial direction of the subject (4,44) before traversing through the subject (4,44), a detector (2) for receiving the collimated radiation (11,12,13,14,15,16) that has traversed through the subject (4,44), and a control unit (7) for controlling the collimator (3) based on at least one geometry parameter that defines a geometrical relationship between the volume of interest (5,45) and the imaging device (100,200). The imaging device (100,200) provides for a reduced dose of radiation applied to the subject (4,44).

Abstract translation: 用于对受试者（4,44）感兴趣的体积（5,45）进行成像的成像装置（100,200）包括用于发射辐射（6）的辐射源（1），其布置成围绕轴线（8 ），用于在穿过被摄体（4,44）之前至少在被检体（4,44）的轴向上校准辐射（6）的准直器（3），检测器（4,44） 2），用于接收已经穿过被摄体的准直辐射（11,12,13,14,15,16），以及用于至少基于控制单元（7）控制准直仪（3）的控制单元（7） 一个几何参数，其定义感兴趣的体积（5,45）和成像装置（100,200）之间的几何关系。 成像装置（100,200）提供施加到对象的减少剂量的辐射（4,44）。

公开(公告)号：WO2008059434A3

公开(公告)日：2008-07-24

申请号：PCT/IB2007054593

申请日：2007-11-12

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  ZIEGLER ANDY ,  KOEHLER THOMAS ,  NIELSEN TIM ,  VAN DER MARK MARTINUS B ,  VAN BEEK MICHAEL C

Inventor： ZIEGLER ANDY ,  KOEHLER THOMAS ,  NIELSEN TIM ,  VAN DER MARK MARTINUS B ,  VAN BEEK MICHAEL C

IPC: A61B5/00 ,  G01J3/44

CPC classification number: A61B5/4312 ,  A61B5/0091 ,  G01N21/4795 ,  G01N21/6456

Abstract: The invention relates to a system, a medical image acquisition system, and a method for imaging an interior of a turbid medium (25). The invention also relates to a marker (60) for use in the method for imaging an interior of a turbid medium (25). The system, the medical image acquisition system, and the method may be used for obtaining an image of an interior of a turbid medium (25) by: accommodation of a turbid medium (25) inside a receiving volume (20); irradiation of the receiving volume (20) with light from a light source; detection of light emanating from the receiving volume (20) as a result of irradiating the receiving volume (20) with light from the light source through the use of a photodetector unit. The detected light is then used to reconstruct an image of an interior of the turbid medium (25). According to the invention, the system, the medical acquisition system, and the method are adapted such that during a measurement the receiving volume (20) comprises at least one marker (60) comprising a predetermined concentration of a chosen fluorescent agent. The light source is arranged for generating excitation light that causes fluorescent emission in the marker (60) and the photodetector is arranged to detect light emanating from the receiving volume (20) as a result of irradiating the receiving volume (20) with excitation light. The use of a marker (60) according to the invention enables obtaining information relating to the geometry of the turbid medium (25). If the turbid medium (25) comprises an unknown concentration of a second fluorescent agent, and the light source and the photodetector unit are arranged for causing fluorescence in the second fluorescent agent and detecting the resulting fluorescence light, respectively, the use of a marker (60) according to the invention enables calibration of the signal resulting from this fluorescence light.

Abstract translation: 本发明涉及一种用于对混浊介质（25）的内部进行成像的系统，医学图像采集系统和方法。 本发明还涉及用于对混浊介质（25）的内部进行成像的方法中使用的标记（60）。 该系统，医学图像采集系统和方法可以用于通过以下操作来获得混浊介质（25）的内部的图像：在容纳体积（20）内容纳混浊介质（25）; 用来自光源的光照射接收体积（20） 作为通过使用光电探测器单元以来自光源的光照射接收体积（20）的结果检测从接收体积（20）发出的光。 然后使用检测到的光重建混浊介质（25）内部的图像。 根据本发明，系统，医疗采集系统和方法适于使得在测量期间，接收容积（20）包括至少一个包含预定浓度的所选荧光剂的标记（60）。 光源被设置用于产生在标记（60）中引起荧光发射的激发光，并且光检测器被设置为检测由于用激发光照射接收体积（20）而从接收体积（20）发出的光。 根据本发明使用标记（60）能够获得与浑浊介质（25）的几何形状有关的信息。 如果混浊介质（25）包含未知浓度的第二荧光剂，并且光源和光电检测器单元被设置为分别在第二荧光剂中引起荧光并检测所得到的荧光，则使用标记（ 60）根据本发明能够校准由该荧光产生的信号。

公开(公告)号：WO2008044188A3

公开(公告)日：2008-07-24

申请号：PCT/IB2007054081

申请日：2007-10-08

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  NIELSEN TIM ,  KOEHLER THOMAS

Inventor： NIELSEN TIM ,  KOEHLER THOMAS

IPC: G01N21/47 ,  A61B5/00

CPC classification number: A61B5/4312 ,  A61B5/0091 ,  G01N21/4795 ,  G01N2021/1787

Abstract: An imaging system for imaging a turbid medium comprises a radiation source to illuminate an object to be imaged. A detection system to detect radiation from the object to produce a plurality of detected radiation levels at respective positions relative to the object. A distinction is made between (i) a central radiation component having passed mainly through an inner region of the object and (ii) a boundary radiation component having passed mainly through a boundary region of the object. On the basis of a comparison of the central radiation component and the boundary radiation component the optical properties, notably optical scattering and optical absorption are derived. From the detected radiation from the object and the optical properties an image of the interior or the object is reconstructed.

Abstract translation: 用于对混浊介质进行成像的成像系统包括照射待成像物体的辐射源。 检测系统检测来自物体的辐射，以在相对于物体的相应位置产生多个检测到的辐射水平。 （i）主要通过物体的内部区域的中心辐射分量和（ii）主要通过物体的边界区域的边界辐射分量之间进行区分。 在比较中心辐射分量和边界辐射分量的基础上，得到光学性质，特别是光学散射和光学吸收。 从检测到的来自物体的辐射和光学特性，重建了内部或物体的图像。

公开(公告)号：WO2007110795A3

公开(公告)日：2008-01-31

申请号：PCT/IB2007050879

申请日：2007-03-14

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  KOEHLER THOMAS ,  SCHLOMKA JENS-PETER

Inventor： KOEHLER THOMAS ,  SCHLOMKA JENS-PETER

IPC: G01T1/29 ,  G01V5/00

CPC classification number: G01T1/2985 ,  A61B6/032 ,  A61B6/037 ,  A61B6/4021 ,  A61B6/4028 ,  A61B6/482 ,  G01V5/0041 ,  G01V5/005 ,  Y10S378/901

Abstract: It is described a method and a CT system for measuring dual-energy X- ray attenuation data of an object. The CT system comprises a rotatable holder, an X-ray source comprising two different X-ray focus points, and an X-ray detection device comprising a plurality of detector elements exhibiting different spectral sensitivities. The method comprises the steps of (a) adjusting the X-ray source such that it emits X-rays originating a first focus point, (b) acquiring first attenuation data separately with first detector elements and with second detector elements, (c) moving the X-ray focus discretely to a second focus point, and (d) acquiring second attenuation data separately with both types of detector elements. Thereby the two focus points are spatially separated from each such that a first beam path originating from the first focus point penetrates a certain voxel within the object and impinges on a first detector element and a second beam path originating from the second X-ray focus point penetrates the same voxel and impinges on a second detector element.

Abstract translation: 描述了用于测量物体的双能X射线衰减数据的方法和CT系统。 CT系统包括可旋转保持器，包括两个不同X射线焦点的X射线源和包括表现出不同光谱灵敏度的多个检测器元件的X射线检测装置。 该方法包括以下步骤：（a）调整X射线源，使其发射源自第一焦点的X射线，（b）分别用第一检测器元件和第二检测器元件获取第一衰减数据，（c）移动 所述X射线焦点离散地到达第二焦点，以及（d）分别用两种类型的检测器元件获取第二衰减数据。 从而两个聚焦点在空间上分离开，使得源自第一聚焦点的第一光束路径穿透物体内的某个体素并撞击在第一X射线焦点上的第一检测器元件和第二光束路径 穿透相同的体素并撞击在第二检测器元件上。