SYSTEMS AND METHODS FOR DETECTING PARTICLES OF INTEREST USING SPECTRAL ANALYSIS

    公开(公告)号:US20240027266A1

    公开(公告)日:2024-01-25

    申请号:US18358798

    申请日:2023-07-25

    Abstract: An example method includes receiving a first set of data that includes spectral metrics provided by a spectral acquisition apparatus that obtains the spectral metrics based on interactions of electromagnetic radiation with a sample. The first set of data is processed to obtain a second set of data that includes the spectral metrics. One or more trained models are applied to the spectral metrics or a set of values based on the spectral metrics to obtain a result. Based on the result, either a positive particle of interest detection or a negative particle of interest detection for the particle of interest for the sample is determined. A particle of interest detection notification that indicates either the positive particle of interest detection or the negative particle of interest detection for the particle of interest for the sample may be generated and provided.

    SAMPLE HOLDER
    52.
    发明申请
    SAMPLE HOLDER 审中-公开

    公开(公告)号:US20180340823A1

    公开(公告)日:2018-11-29

    申请号:US15986894

    申请日:2018-05-23

    Inventor: Eric Schäfer

    CPC classification number: G01J3/0267 G01J3/50 G09F5/04 G09F5/042

    Abstract: There is disclosed a sample holder comprising: a base member; a holder member attached to the base member, the holder member having at least one flexible tab resiliently biased towards the base member; wherein one of the base member and the tab comprises a first formation provided on a face thereof so that a sample having a corresponding second formation can be located between the tab and the base member and retained by cooperation of the first and second formations.

    Biopolymer optical analysis device and method
    54.
    发明授权
    Biopolymer optical analysis device and method 有权
    生物聚合物光学分析装置及方法

    公开(公告)号:US09562809B2

    公开(公告)日:2017-02-07

    申请号:US13812801

    申请日:2011-07-21

    Abstract: The present invention provides a device and method for analyzing the characteristics of a biopolymer with excellent mechanical stability, high spatial resolution and sensitivity using a simple device construction. Specifically, the Raman scattered light of a biopolymer is measured and the properties of monomer units forming the biopolymer are analyzed by using a biopolymer property analysis chip (100a) characterized by comprising: a solid substrate (110); at least one nanopore (120) disposed in the solid substrate (110); and one or more electrically conductive thin films (130a, 130b) disposed on the solid substrate (110). The biopolymer property analysis chip (100a) is characterized in that the electrically conductive thin films (130a, 130b) are disposed partially on the solid substrate (110) where the nanopore (120) is formed and a biopolymer which has penetrated into the nanopore (120) is caused to generate Raman scattered light by means of irradiation with external light.

    Abstract translation: 本发明提供一种使用简单的装置结构分析具有优异机械稳定性,高空间分辨率和灵敏度的生物聚合物的特性的装置和方法。 具体地,测量生物聚合物的拉曼散射光,并通过使用生物聚合物性质分析芯片(100a)分析形成生物聚合物的单体单元的性质,其特征在于包括:固体基材(110); 设置在所述固体基板(110)中的至少一个纳米孔(120); 以及设置在固体基板(110)上的一个或多个导电薄膜(130a,130b)。 生物聚合物性质分析芯片(100a)的特征在于,导电薄膜(130a,130b)部分地设置在形成有纳米孔(120)的固体基板(110)上,并且已经渗透到纳米孔中的生物聚合物 120)通过外部光照射产生拉曼散射光。

    Gas cell for the optical analysis of gases
    58.
    发明申请
    Gas cell for the optical analysis of gases 有权
    用于气体光学分析的气室

    公开(公告)号:US20150185075A1

    公开(公告)日:2015-07-02

    申请号:US14637425

    申请日:2015-03-04

    Abstract: A measuring cell for a gas analysis spectrometer has an inner chamber (23) for a sample gas to be analyzed and an inlet (21) and an outlet (22) which are connected thereto. A traversing optical path for a measuring beam (14) is formed in the inner chamber (23). The measuring cell is tubular, the inlet (21) and the outlet (22) are arranged at opposite ends, and the inner chamber (23) of the measuring cell has a cross-sectional shape that is monotonic over the length of the tube and which has an oval-shape at the start, which disappears toward the end. That special shape results in fast gas exchange and thus high dynamics, even with larger measuring cells, which have high sensitivity due to the long optical paths thereof. Two characteristics which until now appeared to be conflicting are thereby combined.

    Abstract translation: 用于气体分析光谱仪的测量池具有用于待分析样品气体的内室(23)和与其连接的入口(21)和出口(22)。 用于测量光束(14)的横穿光路形成在内腔(23)中。 测量单元是管状的,入口(21)和出口(22)布置在相对端,并且测量单元的内室(23)具有在管的长度上单调的横截面形状, 它在开始时具有椭圆形,最终消失。 这种特殊形状导致快速的气体交换,从而导致高动力学,即使是由于其长的光程而具有高灵敏度的更大的测量单元。 因此,到目前为止,两个特征似乎是相互矛盾的。

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