公开(公告)号：WO2009111834A1

公开(公告)日：2009-09-17

申请号：PCT/AU2009/000295

申请日：2009-03-13

Applicant: RUNCIE, John, W.

Inventor： RUNCIE, John, W.

IPC: G01N21/64 ,  G01N21/01

CPC classification number: G01J1/044 ,  G01N21/645 ,  G01N21/6486 ,  G01N2021/635 ,  G01N2201/0627 ,  G01N2201/0648

Abstract: An automated shutter for dark acclimating a sample, comprising a base and a head mounted to the base and movable between an open and closed position. The automated shutter further comprises one or more artificial light sources and one or more optical detectors disposed in said head or base, and wherein the head is contiguous with the sample when moved into the closed position. Another embodiment comprises an enclosure placed over a sample to be dark acclimatised, with one or more artificial light sources and optical detectors disposed within or closely adjacent to said enclosure which is configured to be transformed between an optically transparent state and an optically opaque state.

Abstract translation: 一种用于暗适应样品的自动快门，包括基座和安装在基座上的头部，可在打开和关闭位置之间移动。 自动快门还包括一个或多个人造光源和设置在所述头部或底座中的一个或多个光学检测器，并且其中当移动到关闭位置时，头部与样品邻接。 另一个实施例包括放置在样本上以适于深色适应的外壳，其中一个或多个人造光源和光学检测器设置在所述外壳内或紧邻所述外壳中，该检测器被配置为在光学透明状态和光学不透明状态之间转换。

公开(公告)号：JP6088510B2

公开(公告)日：2017-03-01

申请号：JP2014520747

申请日：2012-07-20

Applicant: バイオセンシア パテンツ リミテッド

Inventor： モイナハン, シェーン ,  フラビン, ダーミッド

IPC: G01N21/78 ,  G01N33/543

CPC classification number: G01N21/6486 ,  G01N21/645 ,  G01N33/5302 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N21/278 ,  G01N21/6452 ,  G01N2201/0624 ,  G01N2201/0627 ,  G01N2201/0648 ,  G01N2201/0693

公开(公告)号：JP2004519667A

公开(公告)日：2004-07-02

申请号：JP2002567812

申请日：2002-02-27

Applicant: イメージング リサーチ, インク.

Inventor： イエクタ，アーメド ,  ザラテ，カルロス ,  ドンダース，ポール ,  マソウミ，ザーラ ,  ラム，ピーター

IPC: G01N21/64 ,  G01N21/78 ,  G01N33/483

CPC classification number: G01N21/6408 ,  G01N2201/0648

Abstract: 本発明は、生化学的及び医学的サンプルにおける時間分解蛍光をイメージングするための装置及び方法に関する。 主要な態様において、本装置は． アパーチャが大きいレンズと、照明経路にあるフラッシュランプと、発光経路にある高速ソリッドステートシャッタまたはゲート検出器と、マイクロウェルプレート内に分布する複数のウェルに均質な単色照明を送達するための装置と、高量子効率のデジタルカメラと、コンピュータとを含む。 コンピュータ制御下で、ランプは短い間隔でパルシングする。 高速発光シャッタまたはゲート検出器は、カメラの露出を各ランプパルスの消光後数マイクロ秒の期間に制限し、その間に遅延蛍光のみをカメラに伝送する。 本発明は、高感度及び高スループットで複数のサンプルの同時時間分解イメージングを達成する。

公开(公告)号：KR1019970003276B1

公开(公告)日：1997-03-17

申请号：KR1019880003989

申请日：1988-04-08

Applicant: 가부시끼가이샤 메이덴샤

Inventor： 후꾸오까마사요시 ,  마쯔유끼아끼라

IPC: G01N21/62

CPC classification number: G01N21/76 ,  G01N2021/0375 ,  G01N2201/0231 ,  G01N2201/0253 ,  G01N2201/0648

Abstract: 내용없음.

公开(公告)号：KR1019960005091B1

公开(公告)日：1996-04-20

申请号：KR1019920021558

申请日：1992-11-17

Applicant: 가부시키가이샤 신가와

Inventor： 스가하라겐지

IPC: H01L21/66

CPC classification number: H01L24/85 ,  G01N21/8806 ,  G01N2021/887 ,  G01N2201/0648 ,  G01N2201/067 ,  G01R31/2853 ,  G01R31/311 ,  H01L24/45 ,  H01L24/48 ,  H01L24/49 ,  H01L24/78 ,  H01L2224/05554 ,  H01L2224/05624 ,  H01L2224/45144 ,  H01L2224/4809 ,  H01L2224/48091 ,  H01L2224/48245 ,  H01L2224/48247 ,  H01L2224/48465 ,  H01L2224/48624 ,  H01L2224/49171 ,  H01L2224/49175 ,  H01L2224/73265 ,  H01L2224/78 ,  H01L2224/85424 ,  H01L2224/859 ,  H01L2924/00014 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/01019 ,  H01L2924/01039 ,  H01L2924/01079 ,  H01L2924/014 ,  H01L2924/10162 ,  H01L2924/3025 ,  H01L2924/00 ,  H01L2224/05599

Abstract: A bonded wire inspection apparatus for inspecting wires bonded between the pads of a semiconductor chip and the leads of a lead frame including: a vertical illuminator that illuminates an object of inspection from above; an optical assembly that images particular portions of the object such as the ball at one end of a wire and the crescent at another end of the wire, by receiving the light that is emitted from the vertical illuminator and reflected by the object; a camera that photographs the image obtained by the optical assembly; and a diaphragm that is provided beneath the vertical illuminator and electrically changeable in its opening diameter. Thus, by adjusting the opening diameter of the diaphragm, clear images of the object are constantly obtained despite the differences of surface smoothness of the portions to be inspected.

Abstract translation: 一种接合线检查装置，用于检查接合在半导体芯片的焊盘和引线框的引线之间的引线，包括：从上方照射检查对象的垂直照明器; 光学组件，其通过接收从垂直照明器发射并被物体反射的光，对线的一端处的物体（例如球）的特定部分和线的另一端的新月形进行成像; 拍摄由光学组件获得的图像的照相机; 以及设置在垂直照明器下方并且其开口直径可电变化的隔膜。 因此，通过调节隔膜的开口直径，尽管要检查的部分的表面平滑度的差异，仍然始终获得物体的清晰图像。

公开(公告)号：KR1020150016384A

公开(公告)日：2015-02-11

申请号：KR1020147036825

申请日：2013-05-23

Applicant: 지멘스 헬쓰케어 다이아그노스틱스 인크.

Inventor： 재스퍼스,제프리,알.

IPC: G03B9/14

CPC classification number: G02B26/04 ,  G01N21/64 ,  G01N21/645 ,  G01N33/50 ,  G01N2201/0221 ,  G01N2201/0648 ,  G01N2201/068 ,  G03B9/14 ,  G03B11/043 ,  H01J43/00

Abstract: 셔터 어셈블리(shutter assembly)는, 제 1 셔터 블레이드(shutter blade) ― 상기 제 1 셔터 블레이드는 상기 제 1 셔터 블레이드로부터 연장되는 제 1 톱니형 아암(toothed arm) 및 상기 제 1 셔터 블레이드 내의 제 1 광 전송 애퍼처(light transmitting aperture)를 가짐 ―, 및 상기 제 1 셔터 블레이드 근처에 그리고 상기 제 1 셔터 블레이드에 평행하게 포지셔닝(position)된 제 2 셔터 블레이드를 포함한다. 상기 제 2 셔터 블레이드는 상기 제 2 셔터 블레이드로부터 연장되는 제 2 톱니형 아암 및 상기 제 2 셔터 블레이드 내의 제 2 광 전송 애퍼처를 갖는다. 상기 제 1 및 제 2 셔터 블레이드들은 평행 선형 움직임을 허용하도록 지지된다. 모터 기어(motor gear)는, 상기 기어의 회전이, 상기 제 1 및 제 2 광 전송 애퍼처들이 서로에 관하여 오버랩핑 관계(overlapping relationship)에 있는 개방 포지션(open position)과 상기 제 1 및 제 2 광 전송 애퍼처들이 서로에 관하여 비-오버랩핑 관계(non-overlapping relationship)에 있는 폐쇄 포지션(closed position) 사이에서 반대 방향들로 선형으로 상기 제 1 및 제 2 셔터 블레이드들이 움직이게 초래하도록, 상기 제 1 및 제 2 톱니형 아암들 사이에 배치되고, 상기 제 1 및 제 2 톱니형 아암들과 맞물린다.

公开(公告)号：WO2013181052A1

公开(公告)日：2013-12-05

申请号：PCT/US2013/042372

申请日：2013-05-23

Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC. ,  JASPERSE, Jeffrey, R.

Inventor： JASPERSE, Jeffrey, R.

IPC: G03B9/14

CPC classification number: G02B26/04 ,  G01N21/64 ,  G01N21/645 ,  G01N33/50 ,  G01N2201/0221 ,  G01N2201/0648 ,  G01N2201/068 ,  G03B9/14 ,  G03B11/043 ,  H01J43/00

Abstract: A shutter assembly includes a first shutter blade having a first toothed arm extending therefrom and a first light transmitting aperture therein, and a second shutter blade positioned adjacent and parallel to the first shutter blade. The second shutter blade has a second toothed arm extending therefrom and a second light transmitting aperture therein. The first and second shutter blades are supported to allow parallel linear motion. A motor gear is disposed between, and meshed with, the first and second toothed arms such that rotation of the gear causes the first and second shutter blades to move linearly in opposite directions between an open position in which the first and second light transmitting apertures are in an overlapping relationship with respect to one another, and a closed position in which the first and second light transmitting apertures are in a non-overlapping relationship with respect to one another.

Abstract translation: 快门组件包括第一快门叶片，其具有从其延伸的第一齿形臂和其中的第一透光孔，以及邻近并平行于第一快门叶片定位的第二快门叶片。 第二快门叶片具有从其延伸的第二齿形臂和其中的第二透光孔。 支撑第一和第二快门叶片以允许平行线性运动。 马达齿轮设置在第一和第二齿形臂之间并与之啮合，使得齿轮的旋转使得第一和第二快门叶片在第一和第二透光孔之间的打开位置之间沿相反方向线性移动 相对于彼此具有重叠关系，以及闭合位置，其中第一和第二透光孔彼此处于非重叠关系。

公开(公告)号：WO2013014540A3

公开(公告)日：2013-03-28

申请号：PCT/IB2012001907

申请日：2012-07-20

Applicant: BIOSENSIA PATENTS LTD ,  MOYNIHAN SHANE ,  FLAVIN DIARMUID

Inventor： MOYNIHAN SHANE ,  FLAVIN DIARMUID

IPC: G01N21/64 ,  G01N3/44 ,  G01N33/53 ,  G01N33/543 ,  G01N33/58

CPC classification number: G01N21/6486 ,  G01N21/278 ,  G01N21/645 ,  G01N21/6452 ,  G01N33/5302 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2201/0624 ,  G01N2201/0627 ,  G01N2201/0648 ,  G01N2201/0693

Abstract: The present disclosure, among other things, describes a reader system for analyzing one or more analytes in a fluid sample, comprising a casing (204) with at least one port (201) leading to a holster (301) which is configured to receive a cartridge (107) comprising a vertically oriented immunoassay device for analyzing one or more analytes in a fluid sample, an optical system (121) with excitation optics comprising a light source (302) and an excitation lens (305) configured to transmit light from the light source (302) and thereby excite a region of the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), and collection optics comprising a photosensor (306) and a collection lens (307) configured to collect emitted light from the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), an electromechanical motor system (106) configured to move the holster (301) in a vertical direction with respect to the optical system (121) so that the optical system (121) can interrogate different regions of the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), and one or more digital processors (104a, 104b) and associated electronics configured to receive data from and control the optical system (121) and to control the electromechanical motor system (106).

Abstract translation: 本公开尤其描述了一种用于分析流体样品中的一种或多种分析物的读取器系统，其包括具有至少一个通向皮套（301）的端口（201）的壳体（204），所述壳体被配置为接收 盒（107）包括用于分析流体样品中的一种或多种分析物的垂直取向的免疫测定装置，具有激发光学元件的光学系统（121），其包括光源（302）和激发透镜（305），所述光学系统被配置为透射来自 并且由此当盒（107）被放置在机架（301）中时激发垂直取向的免疫测定装置的区域，并且收集光学器件包括光电传感器（306）和收集透镜（307），其被配置为收集 当盒（107）被放置在机架（301）中时，来自垂直取向的免疫测定装置的光发射;机构电动机系统（106），被配置成相对于光学装置在垂直方向上移动机架 cal系统（121），使得当盒（107）被放置在机架（301）中时，光学系统（121）可以询问垂直定向的免疫测定装置的不同区域，以及一个或多个数字处理器（104a，104b）和 配置为从光学系统（121）接收数据和控制光学系统（121）并控制机电马达系统（106）的相关电子设备。

公开(公告)号：WO2007075341A3

公开(公告)日：2007-09-07

申请号：PCT/US2006047581

申请日：2006-12-13

Applicant: HACH CO

Inventor： MITCHELL THOMAS OWEN

IPC: G01N21/64

CPC classification number: G01N21/643 ,  G01N21/8507 ,  G01N2201/0648

Abstract: A method and apparatus for visually detecting when a luminescent dissolved oxygen sensor is operating is disclosed. In one example embodiment of the invention, a shutter (216) is placed into the light tight container. When the shutter (216) is open, a user can see into the light tight container and verify probe operation. When the shutter (216) is closed, external light is prevented from entering the light tight container and affecting measurement accuracy. In another example embodiment of the invention, one end of a light pipe (526) is placed on the outside of the light tight container, and the other end is positioned to view the light source (504) of the probe. In another example embodiment of the invention a second light source (628), visible on the outside of the light tight container, is used to verify operation of the probe. In another example embodiment of the invention, a predetermined area is left open in the optically opaque hydrostatically transparent (814) on the face of the sensor window, allowing a user to see light from the sensor when the sensor is operating properly.

Abstract translation: 公开了一种视觉检测发光溶解氧传感器何时工作的方法和装置。 在本发明的一个示例性实施例中，将快门（216）放置在不透光容器中。 当快门（216）打开时，用户可以看到不透光的容器并验证探头操作。 当快门（216）关闭时，防止外部光进入不透光容器并影响测量精度。 在本发明的另一示例性实施例中，光管（526）的一端放置在不透光容器的外侧，另一端定位成观察探针的光源（504）。 在本发明的另一个示例性实施例中，在不透光容器的外侧可见的第二光源（628）用于验证探针的操作。 在本发明的另一示例性实施例中，在传感器窗口的表面上的光学不透明的静态透明（814）中，预定区域保持打开，从而允许用户在传感器正常工作时看到来自传感器的光。

公开(公告)号：WO00050860A1

公开(公告)日：2000-08-31

申请号：PCT/US2000/004193

申请日：2000-02-18

IPC: G01N21/64 ,  G01J3/30 ,  G01J1/58 ,  G01N21/25

CPC classification number: G01N21/6452 ,  G01N2201/0648

Abstract: An apparatus for measuring light in samples using a high intensity light source (12), is presented. The system utilizes bifurcated fiber bundle (26) to transmit light at the excitation and emission wavelength bands. It also uses a band-pass filter (36) for eliminating extraneous light, including that which corresponds to the excitation wavelength range, while permitting the emitted light to pass to a detector (41) for quantitation. The system employs a shutter (39) to shield the detector (41) while the laser light source is activated, and a controller to intermittently activate the laser light and close the shutter. The apparatus preferably includes lenses (16, 17, 37) for better illumination and read out conditions. The apparatus is employed in Luminescence Oxygen Channeling Immunoassays. The method has high sensitivity, accuracy and precision, and the apparatus is highly compact. Accordingly, the analyzer can perform assays in nanoliter to microliter sample volumes in standard microplates having at least 96, 384 or 1536 wells.

Abstract translation: 提出了一种使用高强度光源（12）测量样品中的光的装置。 该系统利用分叉纤维束（26）在激发和发射波长带发射光。 它还使用带通滤波器（36）来消除包括对应于激发波长范围的外来光，同时允许发射的光通过检测器（41）进行定量。 该系统在激活激光源的同时采用挡板（39）屏蔽检测器（41），并且控制器间歇地激活激光并关闭快门。 该装置优选地包括用于更好地照明和读出条件的透镜（16,17,37）。 该装置用于发光氧通道免疫测定。 该方法灵敏度高，精度高，精度高，设备结构紧凑。 因此，分析仪可以在具有至少96个，384个或1536个孔的标准微孔板中进行纳升至微升样品体积的测定。