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公开(公告)号:KR790000006B1
公开(公告)日:1979-02-26
申请号:KR740002855
申请日:1974-06-21
Applicant: CIBA GEIGY AG
Inventor: ORBAN I , BRUNETTI H , LIND H , RODY J , RASBERGER M
Abstract: 2,2,6,6-Tetramethyl-4-oxopiperidine (I) was prepd. by the reaction of 2,2,4,4,6-pentamethyl-2,3,4,5-tetrahydro pyrimidine (II) with Me2Co, or diaceton alc. 43g IIH2O was reacted with 75g Me2Co and 10 g EtOH at 55≦̸C for 12hr to yield 82% I.
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公开(公告)号:KR780000586B1
公开(公告)日:1978-11-23
申请号:KR780001669
申请日:1978-10-13
Applicant: CIBA GEIGY AG
Inventor: RICCARDO SCARTAZZINI
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公开(公告)号:KR780000293B1
公开(公告)日:1978-08-10
申请号:KR700001001
申请日:1970-07-18
Applicant: CIBA GEIGY AG
Inventor: HUGELSHOFER P
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公开(公告)号:KR880000499B1
公开(公告)日:1988-04-08
申请号:KR850003739
申请日:1985-05-30
Applicant: CIBA GEIGY AG
Inventor: BACK GERHARD , MOSIMANN WALTER
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公开(公告)号:KR840002309B1
公开(公告)日:1984-12-17
申请号:KR800002130
申请日:1980-05-29
Applicant: CIBA GEIGY AG
Inventor: DAVE KRISHNA G , GEORGE THOMAS
IPC: C07D401/12 , A61K31/395 , A61K31/435 , A61P3/08 , A61P3/10 , C07D211/16 , C07D225/02 , C07D295/215 , C07D403/12 , C07D413/12 , C07D419/12
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公开(公告)号:KR840002123B1
公开(公告)日:1984-11-19
申请号:KR790002204
申请日:1979-07-03
Applicant: CIBA GEIGY AG
Inventor: REMPFLER HERMANN , SCHURTER ROLF , BOEHNER BEAT
IPC: C07D213/64 , A01N43/40 , C07D213/643
Abstract: Esters of o-(pyridyloxy-phenyl)-lactic acids[I were prepd. from the reaction of 4-(5-halogenopyridyl-2-oxy) phenol[II ! and esters of - halogenopropionic acids[III in inert organic solvent with the same quantities of base, at 0≦̸C boiling point and normal pressure. Hal is a hlogen atom, X is H or Cl. Y is O or S. Z is substituted or unsubstituted C1-2 alkylene by methyl, cyano, methylcarbonyl or ethoxycarbonyl. Q is OH, C1-2 alkoxy, NH2 or NHC2H5.
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公开(公告)号:KR840001134B1
公开(公告)日:1984-08-09
申请号:KR840002950
申请日:1984-05-29
Applicant: CIBA GEIGY AG
Inventor: WALKER GORDON NOTHROP
IPC: A61K31/40 , A61P29/00 , C07D207/32 , C07D207/337 , C07D207/34 , C07D207/40 , C07D207/416 , C07D261/18
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公开(公告)号:KR820002280B1
公开(公告)日:1982-12-13
申请号:KR790002646
申请日:1979-08-03
Applicant: CIBA GEIGY AG
Inventor: SRINIVASACHARI RAAJARPA , VASUDEVAN SUDARSANAM
IPC: C07D417/06 , A61K31/425 , A61P33/10 , C07D277/42 , C07D295/21
Abstract: Anthelmintic benzimidazoles I(R1 = aliph. or arom. hydro carbon; R2 = H. aliph. hydrocarbon; R3, R4 = H, aliph. or cyclic or arom. hydrocarbon) were prepd. by the reaction of ophenylene diamine and compd. III (Rx = H, COOR1; Ry = CH, substituted methylene). Thus, 4.5 g S-methy1-isothiourea sulfate and 3.5 g ethy1 chloroformate were reacted with 4.5 g 1,2-diamino- 4 - (4-methy1-2-ethylamino-5 - thiazoloy1)-benzene to give 2-carboethoxyamino-5(6)-(4-methy1-2-methylamino-5-thiazoloy1)-benzimid azole(m.p. 250-255oC).
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公开(公告)号:KR820002098B1
公开(公告)日:1982-11-05
申请号:KR790000682
申请日:1979-03-06
Applicant: CIBA GEIGY AG
Inventor: MARXER A
IPC: A61K31/415 , A61K31/4164 , A61P35/00 , C07D233/06 , C07D233/20 , C07D233/22 , C07D233/24 , C07D233/50 , C07D239/42 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/12 , C07D233/04
Abstract: Title compds. I(R1,R2=monocyclic aryl, carbocyclic aryl, hetero aryl; n=0, 1; m=1, 2; p=1, 2; R2=H or lower alkyl; Alk=lower alkylene group; X=H, S; Y=imino group), useful for treating ulcer, were prepd. by reacting compd. II and acid(III). Thus, a mixt. of 1-aminoethyl-2-(2,6-dichloro-anilinomethyl)-2-imidazoline and p-tollyl isocyanate in anhydrous toluene was stirred for 3 hrs at 90≦̸C and condensed to give 1-[2-[2-(2,6-dichloroanilinomethyl)-2-imidazolin-1-yl -ethyl -3-(p-tollyl)-urea, which was dissolved with maleic acid in acetone to give its salt.
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公开(公告)号:KR820000257B1
公开(公告)日:1982-03-10
申请号:KR780003540
申请日:1978-11-23
Applicant: CIBA GEIGY AG
Inventor: BECKER C
IPC: C09B67/00
Abstract: Aq. storage-stable, low-viscosity dispersions of dyes & fluorescent whiteners with particle size 65% ethylene oxide with mol. wt.> 1200, polyol, and auxiliaries. Thus, 400 parts I(dried to a low electrolyte content) was milled with a sulfonated kraft lignin 10, polyethylene-propylene glycol (mol. wt. 16500, 80% ethylene oxide) 20, H2O 398, propylene glycol 170, and preservative 2 parts to give a dye.
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