公开(公告)号：EP4400603A3

公开(公告)日：2024-09-04

申请号：EP24159811.9

申请日：2017-02-10

Applicant: Jumpcode Genomics, Inc.

Inventor： BROWN, Keith

IPC: C12Q1/68 ,  C12N15/10

CPC classification number: C12Q1/6869 ,  C12Q2521/30120130101 ,  C12Q2525/14320130101 ,  C12Q2535/12220130101

Abstract: Disclosed herein are methods of long range target specific amplification and sequencing using an RNA intermediate synthesized directly from the target to eliminate clonal amplification of early synthesis errors. Approaches allow for the identification of target-adjacent sequence, such as sequence adjacent to a repeat element target. Also disclosed herein are compositions and kits for amplification and sequencing.

公开(公告)号：EP4400603A2

公开(公告)日：2024-07-17

申请号：EP24159811.9

申请日：2017-02-10

Applicant: Jumpcode Genomics, Inc.

Inventor： BROWN, Keith

IPC: C12Q1/6869

CPC classification number: C12Q1/6869 ,  C12Q2521/30120130101 ,  C12Q2525/14320130101 ,  C12Q2535/12220130101

Abstract: Disclosed herein are methods of long range target specific amplification and sequencing using an RNA intermediate synthesized directly from the target to eliminate clonal amplification of early synthesis errors. Approaches allow for the identification of target-adjacent sequence, such as sequence adjacent to a repeat element target. Also disclosed herein are compositions and kits for amplification and sequencing.

公开(公告)号：EP4314325A1

公开(公告)日：2024-02-07

申请号：EP22782126.1

申请日：2022-03-30

Applicant: Jumpcode Genomics, Inc.

Inventor： BROWN, Keith ,  ARMSTRONG, Jon ,  SIDDIQUE, Azeem

IPC: C12Q1/68

公开(公告)号：EP4196604A2

公开(公告)日：2023-06-21

申请号：EP21856630.5

申请日：2021-08-11

Applicant: Jumpcode Genomics, Inc.

Inventor： BROWN, Keith

IPC: C12Q1/6806 ,  C12N15/10 ,  C12Q1/6869 ,  C12Q1/6851 ,  C12Q1/6855

公开(公告)号：EP3943615A1

公开(公告)日：2022-01-26

申请号：EP21184021.0

申请日：2015-02-27

Applicant: Jumpcode Genomics, Inc.

Inventor： BROWN, Keith

IPC: C12Q1/6869 ,  C12Q1/6809 ,  C12Q1/6886 ,  G16H15/00

Abstract: Methods and compositions related to the use of Mobile Element Insertions and their adjacent genomic sequences. Methods using MEIs as markers for cellular proliferation, as targets for pharmaceuticals, as markers for tissue fingerprinting and in related methods and compositions are disclosed herein. Methods and compositions relate to the detection, treatment and ongoing monitoring of cell proliferation events, cancer, and deleterious effects of mobile elements in aging, and to the selection, use and monitoring of the success of treatment regimens to address these conditions.

公开(公告)号：EP3924476A1

公开(公告)日：2021-12-22

申请号：EP20754937.9

申请日：2020-02-11

Applicant: Jumpcode Genomics, Inc.

Inventor： BROWN, Keith

IPC: C12N9/22 ,  C12Q1/68 ,  C12Q1/6806