公开(公告)号：WO2022212559A1

公开(公告)日：2022-10-06

申请号：PCT/US2022/022619

申请日：2022-03-30

Applicant: JUMPCODE GENOMICS, INC.

Inventor： BROWN, Keith ,  ARMSTRONG, Jon ,  SIDDIQUE, Azeem

IPC: C12Q1/68

Abstract: Disclosed herein are compositions and methods related to the detection and/or elimination of a first nucleic acid and enrichment of a second nucleic acid in a sample, for example to exclude the first nucleic acid from downstream analysis or sequencing, or to exclude such sequences from a downstream data set.

公开(公告)号：EP3262175A1

公开(公告)日：2018-01-03

申请号：EP16756382.4

申请日：2016-02-25

Applicant: Jumpcode Genomics, Inc. ,  The Scripps Research Institute

Inventor： BROWN, Keith ,  SALOMON, Daniel R. ,  HEAD, Steven ,  SIDDIQUE, Azeem ,  ORDOUKHANIAN, Phillip

IPC: C12N15/113

CPC classification number: C40B40/08 ,  C12N15/1093

Abstract: Methods, compositions and kits are provided herein for insertional modification of nucleic acids by, for example transposase-mediated covalent insertion of insertion sequence into a sample nucleic acid molecule. Using sequence of the insertion to direct amplification of adjacent nucleic acid sequence, and using bar codes to map amplified sequence to partitions, one can map sample nucleic acid sequence to single molecules of the nucleic acid sample that are derived directly from the sample nucleic acid molecule.

公开(公告)号：EP4314325A1

公开(公告)日：2024-02-07

申请号：EP22782126.1

申请日：2022-03-30

Applicant: Jumpcode Genomics, Inc.

Inventor： BROWN, Keith ,  ARMSTRONG, Jon ,  SIDDIQUE, Azeem

IPC: C12Q1/68