64.
    发明专利
    未知

    公开(公告)号:DE69330153T2

    公开(公告)日:2001-09-06

    申请号:DE69330153

    申请日:1993-10-15

    Abstract: An apparatus comprising: a sprayer for inoculating a microbe on a first division divided from at least one sample of a plant to be examined; sample leaving device for leaving a second division divided from the sample not inoculated with the microbe and the first division inoculated with the microbe, for a predetermined period of time under a predetermined condition; first and second photodetector for respectively measuring the quantities of luminescence emitted from the first and second divisions which have been left standing by the sample leaving device; and a computer for comparing the quantities of the luminescence measured by the first and second photodetector, thereby to examine the resistance or sensitivity of the plant to the microbe.

    ANTI-B7-H4 ANTIBODY
    66.
    发明公开
    ANTI-B7-H4 ANTIBODY 审中-公开

    公开(公告)号:EP3492591A1

    公开(公告)日:2019-06-05

    申请号:EP17834307.5

    申请日:2017-07-25

    Abstract: An object is to produce a new anti-B7-H4 antibody having high specificity and affinity and provide a composition for treating cancer making use thereof. A monoclonal antibody that specifically binds to an extracellular domain protein of a human B7-H4 protein is newly produced and an "anti-B7-H4 antibody-effector cell complex" in which the monoclonal antibody and an effector cell are bound in order to enhance the antibody-dependent cellular cytotoxicity of the monoclonal antibody or a bispecific antibody comprising an antigen recognition region of the monoclonal antibody and an effector cell antigen recognition region is further produced and used as a composition for treating cancer.

    METHOD AND KIT FOR DISTINGUISHING BETWEEN PROSTATE CARCINOMA AND BENIGN PROSTATIC HYPERPLASIA
    67.
    发明公开
    METHOD AND KIT FOR DISTINGUISHING BETWEEN PROSTATE CARCINOMA AND BENIGN PROSTATIC HYPERPLASIA 审中-公开
    方法和试剂盒用于之间前列腺癌和良性前列腺增生DISTINCTION

    公开(公告)号:EP2908136A4

    公开(公告)日:2016-06-01

    申请号:EP13846084

    申请日:2013-10-09

    Abstract: An object of the present invention is to provide a method for distinguishing between prostate carcinoma and benign prostatic hyperplasia with high sensitivity and good reproducibility using a small amount of an analyte sample. The method for distinguishing between prostate carcinoma and benign prostatic hyperplasia according to the present invention as a solution means thereof comprises: bringing an analyte sample containing a prostate-specific antigen (PSA) into contact with a carrier having an anti-free PSA antibody immobilized thereon, thereby binding free PSA to the anti-free PSA antibody immobilized on the carrier; thereafter bringing the carrier in which the free PSA is bound to the immobilized anti-free PSA antibody into contact with a monoclonal antibody capable of specifically recognizing a glycan in which a terminal sialic acid residue is bound to galactose through an ±(2,3) bond, thereby binding the monoclonal antibody capable of specifically recognizing a glycan in which a terminal sialic acid residue is bound to galactose through an ±(2, 3) bond to the free PSA bound to the anti-free PSA antibody immobilized on the carrier; measuring the amount of the free PSA having an N-type glycan in which a terminal sialic acid residue is bound to galactose through an ±(2, 3) bond; comparing the measured amount thus obtained with a preset cutoff value for prostate carcinoma and benign prostatic hyperplasia, thereby determining that when the measured amount is larger than the cutoff value, prostate carcinoma is developed or the probability of developing prostate carcinoma is high, and when the measured amount is smaller than the cutoff value, benign prostatic hyperplasia is developed or the probability of developing benign prostatic hyperplasia is high.

    LASER MARKING METHOD
    68.
    发明公开
    LASER MARKING METHOD 审中-公开
    LASERKENNZEICHNUNGSVERFAHREN

    公开(公告)号:EP2392471A4

    公开(公告)日:2014-04-09

    申请号:EP10735795

    申请日:2010-01-26

    Abstract: This invention provides a laser marking method that can form a very minute mark of a predetermined shape, such as a letter or pattern, with clarity and high solidity, on the surface of a substrate. The laser marking method of the invention comprises the steps of (1) depositing a coloring material on the surface of a substrate of thermoplastic material to form a thin film of the coloring material, and (2) applying a laser beam to the thin film of the coloring material in conformity with a predetermined marking shape to cause the portions of the substrate irradiated with the laser beam to soften and to cause the thus softened portions to mix with the coloring material, thereby developing the predetermined marking shape on the surface of the substrate.

    Abstract translation: 本发明提供一种激光打标方法,其能够在基板的表面上形成具有清晰度和高固体性的预定形状(例如字母或图案)的非常微小的标记。 本发明的激光打标方法包括以下步骤:(1)在热塑性材料的基材的表面上沉积着色材料以形成着色材料的薄膜,和(2)将激光束施加到薄膜上 该着色材料与预定的标记形状一致,使得被激光束照射的基板的部分软化并使这些软化部分与着色材料混合,由此在基板的表面上显现出预定的标记形状 。

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