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    SYSTEM AND METHOD FOR MANAGING CASE DATABASE
    5.
    发明申请
    SYSTEM AND METHOD FOR MANAGING CASE DATABASE 审中-公开
    用于管理病例数据库的系统和方法

    公开(公告)号：US20130253954A1

    公开(公告)日：2013-09-26

    申请号：US13848661

    申请日：2013-03-21

    Applicant: FUJIFILM CORPORATION ,  SHIZUOKA PREFECTURE

    Inventor： Keiji Sugihara ,  Masahiro Endo

    IPC: G06F19/00 ,  G06Q50/24

    CPC classification number: G16H10/60 ,  G06F19/321 ,  G06Q50/24 ,  G16H50/70

    Abstract: There is provided a system and method for managing a case database that can enhance the quality of information to be registered. Once a user performs an operation to request registration of a case, it is first searched whether or not a case that can be determined to be similar to the case has already been registered in a case database. A result of the search is then reported, while executable processing options determined based on the result of the search are also reported. If the case that can be determined to be similar has already been registered, the executable processing options include processing of registering as a new case, processing of registering by adding into an existing case, and processing of cancelling registration. If the case that can be determined to be similar has not been registered, the executable processing options include processing of registering as a new case and processing of cancelling registration. The user selects processing to be executed out of the reported executable processing options. Accordingly, only the cases truly needed by the user can be registered into the case database.

    Abstract translation: 提供了一种用于管理案例数据库的系统和方法，其可以提高要注册的信息的质量。 一旦用户执行请求案件注册的操作，首先搜索可以确定为与案例类似的情况是否已经被注册在案例数据库中。 然后报告搜索的结果，同时报告基于搜索结果确定的可执行处理选项。 如果可以确定为相似的情况已经被注册，则可执行处理选项包括作为新情况的注册处理，通过添加到现有情况下的注册处理以及取消注册的处理。 如果可以确定为相似的情况尚未登记，则可执行处理选项包括作为新情况的注册处理和取消注册的处理。 用户从报告的可执行处理选项中选择要执行的处理。 因此，仅将用户真正需要的情况登记到案件数据库中。

    SYSTEM AND METHOD FOR RETRIEVAL TREATMENT OF PROTEINS IN FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUE SECTION
    7.
    发明申请
    SYSTEM AND METHOD FOR RETRIEVAL TREATMENT OF PROTEINS IN FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUE SECTION 审中-公开
    蛋白质固定化嵌合嵌体组织蛋白质检索系统及方法

    公开(公告)号：US20160153872A1

    公开(公告)日：2016-06-02

    申请号：US14978115

    申请日：2015-12-22

    Applicant: SHIMADZU CORPORATION ,  SHIZUOKA PREFECTURE

    Inventor： Yutaka AOKI ,  Yukari UMINO ,  Taka-Aki SATO ,  Isamu HAYASHI ,  Keiichi HATAKEYAMA ,  Shun-ichiro OGURA

    IPC: G01N1/30 ,  G01N33/68

    CPC classification number: G01N1/30 ,  G01N33/68 ,  G01N33/6848

    Abstract: A protein retrieval treatment system used for activating proteins contained in a deparaffinized tissue section obtained by removing paraffin from a formalin-fixed paraffinembedded tissue section. The protein retrieval treatment system includes: a dispensing unit for dispensing a retrieval treatment solution over a dispensing area including a measurement area on the deparaffinized tissue section; and a moist-heat treatment unit for heating, in a saturated water vapor, the deparaffinized tissue section with the dispensing area covered with the retrieval treatment solution.

    Abstract translation: 一种蛋白质回收处理系统，用于激活通过从福尔马林固定的石蜡包裹的组织切片中除去石蜡而获得的脱石蜡组织切片中所含的蛋白质。 蛋白质回收处理系统包括：分配单元，用于在包括脱蜡组织部分上的测量区域的分配区域上分配回收处理溶液; 以及湿热处理单元，用于在饱和水蒸汽中加热脱蜡组织部分，其中所述分配区域被所述回收处理溶液覆盖。

    METHOD FOR DETECTING THE DEGREE OF MALIGNANCY OF EACH OF THE CIRCULATING TUMOR CELLS, AND A KIT FOR THE SAME
    8.
    发明申请
    METHOD FOR DETECTING THE DEGREE OF MALIGNANCY OF EACH OF THE CIRCULATING TUMOR CELLS, AND A KIT FOR THE SAME 审中-公开
    检测循环肿瘤细胞恶性程度的方法及其相关试剂盒

    公开(公告)号：US20150064722A1

    公开(公告)日：2015-03-05

    申请号：US14388445

    申请日：2013-03-28

    Applicant: ON-CHIP BIOTECHNOLOGIES CO., LTD. ,  SHIZUOKA PREFECTURE

    Inventor： Kazuo Takeda ,  Namiko Yamashita ,  Yuu Fujimura ,  Kaori Nishio ,  Yasuhiro Koh ,  Masaru Watanabe ,  Fumiaki Koizumi ,  Yuri Uehara

    IPC: G01N33/574

    CPC classification number: G01N33/57492 ,  C12N5/0693 ,  G01N33/574 ,  G01N33/58 ,  G01N33/582

    Abstract: The object of the present invention is to provide an evaluation method capable of accurately determining a metastasis of cancer, the stage of cancer progression, or the malignancy of cancer.The object can be solved by a method for detecting the degree of malignancy of each of the circulating tumor cells, characterized by the following steps: (a) bringing an epithelial cell-binding component, which specifically binds to a marker molecule expressed on epithelial cells and is fluorescently-labeled or luminescent enzyme-labeled, and a mesenchymal cell-binding component, which specifically binds to a marker molecule expressed on mesenchymal cells and is fluorescently-labeled or luminescent enzyme-labeled, into contact with a sample that possibly contains circulating tumor cells, (b) detecting a fluorescence signal or a luminescence signal of the epithelial cell-binding component and a fluorescence signal or a luminescence signal of the mesenchymal cell-binding component of each of the cells, and (c) determining the degree of epithelial-mesenchymal transition of circulating tumor cells based on the signal amount of the epithelial cell-binding component (E) and the signal amount of the mesenchymal cell-binding component (M).

    Abstract translation: 本发明的目的是提供能够准确地确定癌症转移，癌症进展阶段或癌症恶性的评价方法。 可以通过检测每个循环肿瘤细胞的恶性程度的方法来解决该问题，其特征在于以下步骤：（a）使上皮细胞结合成分与上皮细胞上表达的标志物分子特异性结合 并且被荧光标记或发光酶标记，和间充质细胞结合组分，其特异性结合于在间充质细胞上表达并被荧光标记或发光酶标记的标记分子与可能含有循环的样品接触 肿瘤细胞，（b）检测上皮细胞结合成分的荧光信号或发光信号，以及每个细胞的间充质细胞结合成分的荧光信号或发光信号，（c） 基于上皮细胞结合组分（E）的信号量和循环肿瘤细胞的信号量的上皮 - 间质转化 的间充质细胞结合成分（M）。

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