公开(公告)号：AU2018250497A1

公开(公告)日：2018-11-15

申请号：AU2018250497

申请日：2018-10-19

Applicant: STRECK INC

Inventor： KREIFELS MATTHEW R ,  WHITNEY SCOTT E ,  WILDER GREGG ,  FLANAGAN JOHN ,  DOWLING JAMES ,  HILL PHILIP ,  TILLEMAN MICHAEL ,  JACKSON JEREMIE

IPC: G01N21/64 ,  B01L7/00 ,  C12Q1/68

Abstract: DEVICES FOR REAL-TIME POLYMERASE CHAIN REACTION An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate detection of stationary samples, reduced sample read time, and simultaneous reading of multiple light wavelengths. 13-7

公开(公告)号：SI2814981T1

公开(公告)日：2017-11-30

申请号：SI201330792

申请日：2013-02-13

Applicant: STRECK INC

Inventor： RYAN WAYNE L ,  FERNANDO M ROHAN ,  DAS KAUSIK

IPC: C12Q1/00

公开(公告)号：DE202010018569U1

公开(公告)日：2017-09-26

申请号：DE202010018569

申请日：2010-02-11

Applicant: STRECK INC

IPC: C12Q1/68

Abstract: Blutsammelröhrchen zur Stabilisierung von Nukleinsäuren innerhalb einer entnommenen Blutprobe, wobei das Blutsammelröhrchen ein Schutzmittel enthält, welches – ein Konservierungsmittel ausgewählt aus Diazolidinylharnstoff, Imidazolidinylharnstoff und einer beliebigen Kombination davon, und – einen Nukleasehemmer ausgewählt aus der Gruppe bestehend aus Diethylpyrocarbonat, Ethanol, Aurintricarbonsäure (ATA), Formamid, Vanadyl-Ribonukleosid-Komplexe, Macaloid, Ethylendiamintetraessigsäure (EDTA), Proteinase K, Heparin, Hydroxylamin-Sauerstoff-Kupfer(II)ion, Bentonit, Ammoniumsulfat, Dithiothreitol (DTT), Beta-Mercaptoethanol, Cystein, Dithioerythrit, Tris-(2-carboxyethyl)phosphen-Hydrochlorid oder ein zweiwertiges Kation wie Mg+2, Mn+2, Zn+2, Fe+2, Ca+2, Cu+2 und eine beliebige Kombination davon umfasst; wobei die Innenwand des Blutsammelröhrchens eine Polymerbeschichtung aufweist ausgewählt aus siliciumhaltigen Polymeren, Polyolefinen, Polyethylenterephthalat, fluorierten Polymeren, Polyvinylchlorid, Polystyrol und einer beliebigen Kombination davon.

公开(公告)号：DE202010018545U1

公开(公告)日：2017-08-07

申请号：DE202010018545

申请日：2010-01-20

Applicant: STRECK INC

IPC: C12Q1/68

Abstract: Blutsammelröhrchen für nichtinvasives pränatales Screening zur Identifizierung fötaler Merkmale, enthaltend: ein Nukleinsäureschutzmittel, welches Imidazolidinylharnstoff und Ethylendiamintetraessigsäure (EDTA) enthält; wobei das Schutzmittel verhindert, dass Blutzellen (i) genomische Nukleinsäuren in eine Blutprobe freisetzen und (ii) Nukleaseaktivität erfahren, die fötale Nukleinsäure abbaut.

公开(公告)号：ES2617147T3

公开(公告)日：2017-06-15

申请号：ES10000518

申请日：2010-01-20

Applicant: STRECK INC

Inventor： FERNANDO M ROHAN ,  CHAO-WEI CHEN KATE

IPC: C12Q1/68

Abstract: Un procedimiento exploratorio no invasivo prenatal para la identificación de características fetales, que comprende las etapas de: poner en contacto una muestra de sangre materna extraída, que incluye una pluralidad de células sanguíneas, con un agente protector de ácido nucleico, para evitar que las células sanguíneas (i) liberen ácidos nucleicos genómicos a la muestra de sangre y (ii) experimenten una actividad nucleasa que degrade los ácidos nucleicos fetales; aislar los ácidos nucleicos fetales de la muestra de sangre materna; y analizar los ácidos nucleicos fetales aislados para identificar una característica fetal en el que el agente protector incluye glicina e imidazolidinil urea, y ácido etilendiaminotetraacético en el que el agente protector contiene menos del 1 % en peso de formaldehído.

公开(公告)号：CA2538968C

公开(公告)日：2015-03-31

申请号：CA2538968

申请日：2006-03-08

Applicant: STRECK INC

Inventor： HUNSLEY BRADFORD A ,  RYAN WAYNE L

IPC: A61B5/153 ,  G01N15/05

Abstract: Improvements in blood collection and testing. In one aspect, an improved method of manufacturing a blood collection tube, particularly illustrated for use in sedimentation rate testing, including providing an elongated glass tube with an open first end for receiving a venipuncture blood sample of at least 1 ml, formed with a closed end opposite the first end; and applying to a substantial portion of the receptacle a containment barrier. The improvements also pertain to resulting blood collection tubes, additives for blood collection tubes that permit reliable sedimentation test data after 8 hours from the blood draw, and methods of administering health care using the aforenoted tubes, additives or both.

公开(公告)号：CA2917912A1

公开(公告)日：2015-01-29

申请号：CA2917912

申请日：2014-07-22

Applicant: STRECK INC

Inventor： FERNANDO M ROHAN ,  RYAN WAYNE L ,  HUNSLEY BRAD

IPC: A01N1/02 ,  G01N33/574

Abstract: Compositions and Methods for Stabilizing Circulating Tumor Cells Methods and compositions for stabilizing a biological sample for analysis, comprising the steps of obtaining in a sample collection device a biological sample from a subject, especially blood, the biological sample including at least one circulating tumor cell from the subject. The methods may include a step of contacting the biological sample with a protective agent composition that includes a preservative agent, an optional anticoagulant, and a quenching agent to form a mixture that includes the protective agent composition and the sample.

公开(公告)号：CA2879638A1

公开(公告)日：2014-02-13

申请号：CA2879638

申请日：2013-03-15

Applicant: STRECK INC

Inventor： KREIFELS MATTHEW R ,  WHITNEY SCOTT E ,  TERMAAT JOEL R

IPC: G01N21/64

Abstract: A device and system for facilitating polymerase chain reaction analysis including a light source (46), photodiodes (44), multi- branched waveguides (32), and filters (40) that occupy minimal space and allow reduced sample read time and rapid reading of multiple light wavelengths.

公开(公告)号：CA2690651A1

公开(公告)日：2011-01-22

申请号：CA2690651

申请日：2010-01-21

Applicant: STRECK INC

Inventor： FERNANDO M ROHAN ,  CHAO-WEI CHEN KATE

IPC: C12N15/10 ,  C12Q1/68

Abstract: A method for preserving and processing fetal nucleic acids located within maternal plasma is disclosed, wherein a sample of maternal blood containing fetal nucleic acids is treated to reduce both cell lysis of the maternal blood cells and deoxyribonuclease (DNase) and ribonuclease (RNase) activity within the fetal nucleic acids. The treatment of the sample aids in increasing the amount of fetal nucleic acids that can be identified and tested while maintaining the structure and integrity of the fetal nucleic acids.

公开(公告)号：US20230302454A1

公开(公告)日：2023-09-28

申请号：US18020893

申请日：2021-08-13

Applicant: STRECK, INC.

Inventor： Sean Salamifar ,  Nick George ,  Brad Hunsley

IPC: B01L3/00

CPC classification number: B01L3/5082 ,  B01L2200/16 ,  B01L2300/16

Abstract: The present teachings relate to a method of making a biological sample collection container, an internally coated biological sample collection container, and uses of the same, particularly for omic analysis. A reagent (or a reagent precursor) is deposited in a liquid state at least partially along at least one side wall of the container. The reagent precursor is dried to form a dried coating having a predefined pattern and topology along at least a portion of the at least one side wall. A container thus results having a coating that includes, in a dried state, a stabilizer agent, or reaction product of a stabilizer agent and an anticoagulant, and upon collection of a sample enables stabilization of any present white blood cells, cell-free nucleic acids, extracellular vesicles, circulating tumor cells, proteins, metabolites, lipids, or any combination thereof, and preserving them in sufficient quantity and quality for omic analysis.