리그난 유도체를 함유하는 세라마이드 대사관련 효소에 의해 매개되는 질환의 예방 또는 치료용 조성물
    61.
    发明公开
    리그난 유도체를 함유하는 세라마이드 대사관련 효소에 의해 매개되는 질환의 예방 또는 치료용 조성물 有权
    用于预防或治疗包含作为活性成分的Larianan衍生物的CERAMIDE代谢相关酶介导的疾病的组合物

    公开(公告)号:KR1020100059050A

    公开(公告)日:2010-06-04

    申请号:KR1020080117688

    申请日:2008-11-25

    CPC classification number: A61K31/192 A61K31/343

    Abstract: PURPOSE: A composition containing lignin derivative is provided to treat atopic dermatitis or xerosis to also treat diseases mediated by ceramide metabolic enzyme. CONSTITUTION: A composition for preventing or treating diseases mediated by ceramide metabolic enzyme contains rosmarinic acid of chemical formula 1, lithospermic acid of chemical formula 2, 9"-methyl lithospermate of chemical formula 2, or lignin derivative of 9'-methyl lithospermate of chemical formula 2 as an active ingredient. The composition enhances ceramide content on the epidermis.

    Abstract translation: 目的:提供含有木质素衍生物的组合物治疗特应性皮炎或干性病,还可治疗由神经酰胺代谢酶介导的疾病。 构成:用于预防或治疗由神经酰胺代谢酶介导的疾病的组合物含有化学式1的迷迭香酸,化学式2的化学式2,化学式2的9“ - 甲基紫精的化学式,或化学式为9'-甲基紫苏的木质素衍生物 配方2作为活性成分。组合物增强表皮上的神经酰胺含量。

    항산화 물질의 산화촉진 부작용을 감소시키는 방법
    63.
    发明授权
    항산화 물질의 산화촉진 부작용을 감소시키는 방법 有权
    用于预防抗氧化剂的氧化副作用的方法

    公开(公告)号:KR100835866B1

    公开(公告)日:2008-06-09

    申请号:KR1020070001413

    申请日:2007-01-05

    Abstract: A method for reducing the pro-oxidant side effects of an antioxidant substance is provided to enhance the effects of an antioxidant composition in health promotion and aging prevention. A method for reducing the pro-oxidant side effects of an antioxidant substance comprises: mixing saccharide to a composition containing an antioxidant substance. The saccharide is selected from the group consisting of monosaccharide such as dextrose, disaccharide such as lactose, and alcohol sugar such as maltitol. The antioxidant substance comprises vitamin C, epigallocatechin-3-gallate(EGCG), proanthocyanidin, or gallic acid. The weight of the saccharide is equal to or more than that of the antioxidant substance contained in the composition.

    Abstract translation: 提供降低抗氧化剂的促氧化剂副作用的方法,以增强抗氧化剂组合物在健康促进和防老化中的作用。 减少抗氧化剂的促氧化剂副作用的方法包括:将糖与含有抗氧化物质的组合物混合。 糖类选自单糖如葡萄糖,二糖如乳糖和醇糖如麦芽糖醇。 抗氧化物质包括维生素C,表没食子儿茶素-3-没食子酸酯(EGCG),原花青素或没食子酸。 糖的重量等于或大于组合物中所含的抗氧化剂物质的重量。

    수용성 항산화 물질 및 지용성 항산화 물질을 동시에함유하는 항산화 조성물
    64.
    发明公开
    수용성 항산화 물질 및 지용성 항산화 물질을 동시에함유하는 항산화 조성물 无效
    含有可溶性抗氧化材料和脂溶性材料的防氧化组合物

    公开(公告)号:KR1020080049610A

    公开(公告)日:2008-06-04

    申请号:KR1020070103465

    申请日:2007-10-15

    Abstract: An anti-oxidative composition is provided to show synergetic effect as an antioxidizing agent by mixing a water-soluble anti-oxidative material with an oil-soluble anti-oxidative material, reduce possible side effects caused by taking a single anti-oxidative material and increase the maintenance time of in vivo anti-oxidation efficacy. An anti-oxidative composition comprises a water-soluble anti-oxidative material such as vitamin C, epigallocatechin-3-gallate(EGCG), proanthocyanidin and gallic acid and an oil-soluble anti-oxidative material such as vitamin E, curcumin, carotene, lipoic acid and coenzyme Q10. Further, the water-soluble anti-oxidative material and the oil-soluble anti-oxidative material are mixed at a weight rate of 1:2 to 4:1.

    Abstract translation: 提供抗氧化组合物以通过将水溶性抗氧化剂材料与油溶性抗氧化材料混合来显示作为抗氧化剂的协同作用,减少由于使用单一抗氧化材料而引起的可能的副作用并增加 维持时间的体内抗氧化功效。 抗氧化组合物包含水溶性抗氧化物质如维生素C,表没食子儿茶-3-没食子酸酯(EGCG),原花青素和没食子酸,以及油溶性抗氧化物质如维生素E,姜黄素,胡萝卜素, 硫辛酸和辅酶Q10。 此外,将水溶性抗氧化剂材料和油溶性抗氧化剂材料以1:2至4:1的重量比混合。

    GCG 고함량 녹차 및 그 제조방법
    65.
    发明公开
    GCG 고함량 녹차 및 그 제조방법 无效
    含有GCG(GALLOCATECHIN-3-GALLATE)的高含量的绿茶及其制备方法

    公开(公告)号:KR1020080006895A

    公开(公告)日:2008-01-17

    申请号:KR1020060066207

    申请日:2006-07-14

    Abstract: A method of manufacturing green tea with a high content of Gallocatechin-3-gallate(GCG) by subjecting green tea leaf to steam treatment at high temperature and pressure to epimerize epigallocatechin-3-gallate(EGCG) after steaming or roasting treatment of the green tea leaf is provided to increase the content of GCG by a thermal conversion method. To make green tea with a high content of Gallocatechin-3-gallate, green tea leaf is treated with steam or roasted. In the process, the steam treatment is performed more than 2 times or roasting time is increased by more than 20%. The steam treatment or roasting is performed within 30min. After the steam treatment or roasting, steam sterilization treatment is additionally performed for 1 to 240min.

    Abstract translation: 一种通过在高温高压下对绿茶叶进行蒸汽处理来制造具有高含量的Gallocatechin-3-没食子酸酯(GCG)的绿茶的方法,以在对绿色的蒸汽或焙烧处理后对表没食子儿茶素-3-没食子酸酯(EGCG)进行差向异构化 提供茶叶以通过热转化方法增加GCG的含量。 为了制备高含量的Gallocatechin-3-没食子酸酯的绿茶,用蒸汽或焙烤处理绿茶叶。 在此过程中,蒸汽处理时间超过2次,焙烧时间提高20%以上。 蒸汽处理或焙烧在30分钟内进行。 蒸汽处理或焙烧后,进行1〜240分钟的蒸汽灭菌处理。

    이성질체화를 통한 갈로카테킨 갈레이트 제조방법
    66.
    发明公开
    이성질체화를 통한 갈로카테킨 갈레이트 제조방법 无效
    通过反应制备GALLOCATECHIN GALLATE的制备方法

    公开(公告)号:KR1020080004906A

    公开(公告)日:2008-01-10

    申请号:KR1020060063824

    申请日:2006-07-07

    CPC classification number: C07D311/58

    Abstract: A method for preparing gallocatechin gallate is provided to increase the solubility of epigallocatechin gallate into a reaction solvent by using an organic solvent and increase the conversion rate into the gallocatechin gallate through epimerization by adjusting the pH, thereby capable of increasing the production amount of the gallocatechin gallate. A method for preparing gallocatechin gallate comprises a step of converting epigallocatechin gallate into the gallocatechin gallate by dissolving the epigallocatechin gallate in an alcohol-based solvent such as ethanol and methanol or a polyol based solvent such as butylene glycol, propylene glycol and polyethylene glycol and then heating the solution at a temperature of about 120 deg.C for 30-60 minutes.

    Abstract translation: 提供了没食子儿茶素没食子酸酯的制备方法,以通过使用有机溶剂提高表没食子儿茶素没食子酸酯在反应溶剂中的溶解度,并通过调节pH提高通过差向异构化得到的儿茶素没食子酸酯的转化率,从而能够增加喜树碱的产生量 没食子酸酯。 没食子酸儿茶素没食子酸酯的制备方法包括将表没食子儿茶素没食子酸酯溶解在醇类溶剂如乙醇和甲醇或多元醇类溶剂如丁二醇,丙二醇和聚乙二醇中,将表没食子儿茶素没食子酸酯转化为喜树碱没食子酸酯,然后 在约120℃的温度下加热溶液30-60分钟。

    피지분비 억제용 조성물
    67.
    发明公开
    피지분비 억제용 조성물 有权
    能够抑制皮脂分泌的组合物

    公开(公告)号:KR1020070094340A

    公开(公告)日:2007-09-20

    申请号:KR1020060024905

    申请日:2006-03-17

    Abstract: 본발명은녹차성분및 백자인추출물을함유하여피지분비억제효과를나타내는화장료조성물에관한것으로, 더욱상세하게는녹차추출물또는녹차구성성분인카테킨(catechins)류, 플라보놀 (flavonols)류및 그유도체로이루어진군에서선택된 1종이상과백자인추출물을일정한성분비로함유함으로써과잉피지억제효과및 여드름완화효과를갖는화장료조성물에관한것이다.

    Abstract translation: 提供化妆品组合物,以一定比例包含绿茶或绿茶提取物中含有的成分和东方蓟马提取物,以一定比例控制皮脂的代谢,从而有效减轻或改善痤疮并抑制过多的皮脂。 化妆品组合物包含0.001-30.0重量%的绿茶成分,例如绿茶,儿茶素,黄酮醇或其衍生物作为有效成分的提取物,以及Thujae orientalis Semen的提取物,其中儿茶素是表没食子儿茶素(EGCG) ,并且没食子儿茶素没食子酸gallocatechin(GCG)和黄酮醇是槲皮素,山奈酚和杨梅素。

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