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公开(公告)号：KR1020140130383A
公开(公告)日：2014-11-10
申请号：KR1020140124116
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
CPC classification number: C12Q1/6844 , C12Q1/6813
Abstract: 민감성 피부에 대해서 특이적으로 유전자 발현량이 증가 또는 억제되는 바이오 마커가 개시된다. 상기 민감성 피부에 특이적인 바이오 마커를 이용하여 민감성 피부 진단 키트 및 자극감 완화제의 스크리닝 방법 등에 활용할 수 있다.
Abstract translation: 公开了具有基因表达的生物标志物，其对于敏感性皮肤特异性地增加或减少。 敏感皮肤特异性的生物标志物用于敏感皮肤的这种诊断试剂盒和刺激释放剂的筛选方法。 诊断试剂盒包括：一种或多种作为ATF4转录因子基因多核苷酸的多核苷酸或其片段，其中所述片段包含十个或更多个连续核苷酸，或与该片段互补的多核苷酸和多核苷酸; 和具有多核苷酸结合表面的固体支持物。
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公开(公告)号：KR1020140130381A
公开(公告)日：2014-11-10
申请号：KR1020140124113
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
CPC classification number: C12Q1/6844
Abstract: 민감성 피부에 대해서 특이적으로 유전자 발현량이 증가 또는 억제되는 바이오 마커가 개시된다. 상기 민감성 피부에 특이적인 바이오 마커를 이용하여 민감성 피부 진단 키트 및 자극감 완화제의 스크리닝 방법 등에 활용할 수 있다.
Abstract translation: 公开了具有基因表达的生物标志物，其对于敏感性皮肤特异性增加或降低。 敏感皮肤特异性的生物标志物用于敏感皮肤的这种诊断试剂盒和刺激释放剂的筛选方法。 诊断试剂盒包括：一种或多种多核苷酸作为LPL基因的多核苷酸或其片段，其中该片段包含十个或更多个连续核苷酸，或与片段互补的多核苷酸和多核苷酸; 和具有多核苷酸结合表面的固体支持物。
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公开(公告)号：KR101349249B1
公开(公告)日：2014-01-10
申请号：KR1020070085431
申请日：2007-08-24
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 사람 유래 세포 표면 및 세포배양액에서 발현되는 지표를 측정하여 화장품 원료 또는 기타 물질의 피부 감작성을 평가하는 시험관내 피부 감작성 평가방법과 이 평가방법을 통해 도출된 데이터로부터 물질의 감작성 유발 가능성을 등급화하는 방법에 관한 것이다.
피부 감작성, CD86, CD54, CD83-
公开(公告)号：KR1020100060679A
公开(公告)日：2010-06-07
申请号：KR1020080119374
申请日：2008-11-28
Applicant: (주)아모레퍼시픽
IPC: A61K36/534 , A61P17/00
Abstract: PURPOSE: A composition containing plant extract having different irritation relief mechanism is provided to suppress prostaglandin-E2 and activate secretion of alpha-melanocyte stimulating hormone. CONSTITUTION: A composition for relieving skin irritation and inflammation contains Rubus Idaeus fruit extract, Mentha piperita extract, and Boerhavia diffusa Root Extract as an active ingredient. The weight ration of the mixture is 1-4:1-8:1-8. The active ingredient relieves skin irritation and inflammation by retinoic acid or sldium lauryl sulfate. The composition is used in the form of an external use skin formulation. The composition is used in the form of skin, lotion, massage cream, nutrition cream, pack, gel, or skin additive cosmetic.
Abstract translation: 目的：提供含有不同刺激缓解机制的植物提取物的组合物，以抑制前列腺素E2，并激活α-黑素细胞刺激激素的分泌。 构成：用于缓解皮肤刺激和炎症的组合物含有Rubus Idaeus水果提取物，Mentha piperita提取物和Boerhavia diffusa Root Extract作为活性成分。 混合物的重量比为1-4：1-8：1-8。 活性成分通过视黄酸或十二烷基硫酸钠缓解皮肤刺激和炎症。 组合物以外用皮肤制剂的形式使用。 该组合物以皮肤，洗剂，按摩霜，营养霜，包装，凝胶或皮肤添加剂化妆品的形式使用。
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Patent Agency Ranking
公开(公告)号：KR1020100060599A
公开(公告)日：2010-06-07
申请号：KR1020080119251
申请日：2008-11-28
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition containing Glechoma hederacea extract, peppermint extract, and biosaccharide gum-2 is provided to protect skin from outer irritation and to normalize sensitive skin. CONSTITUTION: A cosmetic composition for relieving irritation contains 0.01-5 weight% of mixture perppermint extract and biosaccharide gum-2 as active ingredients. The cosmetic composition is used in the form of skin, lotion, massage cream, nutrition cream, pack, gel, ointment, gel, cream, patch, or spray. The cosmetic composition further contains active ingredients for skin whitening, anti-aging, or anti-wrinkle.
Abstract translation: 目的：提供含有Glechoma hederacea提取物，薄荷提取物和生物糖胶-2的化妆品组合物，以保护皮肤免受外部刺激和使皮肤正常化。 构成：用于缓解刺激的化妆品组合物含有0.01-5重量％的混合珍珠提取物和生物糖胶-2作为活性成分。 化妆品组合物以皮肤，洗剂，按摩霜，营养霜，包装，凝胶，软膏，凝胶，霜，贴剂或喷雾剂的形式使用。 化妆品组合物还含有用于皮肤美白，抗衰老或抗皱的活性成分。
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公开(公告)号：KR1020090123049A
公开(公告)日：2009-12-02
申请号：KR1020080048930
申请日：2008-05-27
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
CPC classification number: C12Q1/6883 , C12Q2600/136
Abstract: PURPOSE: A biomarker of which expression is specifically decreased or suppressed in the sensitive skin is provided to quickly diagnose sensitive skin and used for screening a relieving agent. CONSTITUTION: A biomarker for diagnosing sensitive skin contains gene of which expression is decreased or increased in the sensitive skin compared to healthy skin or a protein encoding the gene. A method for screening a relieving agent of sensitivity comprises: a step of conjugating a candidate agent to a protein encoded by a gene of which expression is increased or decreased in the sensitive skin; and a step of confirming the suppression of protein activity.
Abstract translation: 目的：提供敏感皮肤中特异性降低或抑制表达的生物标志物，以快速诊断敏感皮肤并用于筛选缓解剂。 构成：与健康皮肤或编码该基因的蛋白质相比，用于诊断敏感皮肤的生物标志物含有敏感皮肤中表达降低或增加的基因。 用于筛选敏感性缓释剂的方法包括：将候选试剂与由敏感皮肤中表达增加或减少的基因编码的蛋白质缀合的步骤; 以及确认蛋白质活性抑制的步骤。
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公开(公告)号：KR1020080024653A
公开(公告)日：2008-03-19
申请号：KR1020060089036
申请日：2006-09-14
Applicant: (주)아모레퍼시픽
IPC: G06Q50/22
CPC classification number: G06Q50/22
Abstract: A method for calculating a dangerous level of skincare claim and an information providing system thereof are provided to determine precisely and grade the dangerous level of the skincare claim caused by cosmetics, analyze the skincare claim easily in real-time, and transfer an analysis result quickly to a related department. A receiver(10) receives skincare claim from customers and manages a one-time skincare side effect claim, and a main server(20) communicates with the receiver through the network. A database(30) stores product information, consultation information, a score of each monitoring item, a skincare side effect score, a skincare side effect claim ratio, and management information of each dangerous level. An analysis system(40) includes an algorithm scoring the skincare side effect claim based on the score of each monitoring item and the consultation information, an engine calculating the skincare side effect claim ratio based on the consultation and product information, and a matrix grading the dangerous level from the skincare side effect score and the skincare side effect claim ratio according to a fuzzy logic. A related department(50) receives the management in an alarm type according to the dangerous level from the main server.
Abstract translation: 提供了一种计算危险级别的护肤品及其信息提供系统的方法，用于精确地确定化妆品引起的护肤品的危险等级，并轻松地分析护肤品要求并快速转移分析结果 到相关部门。 接收器（10）从客户接收护肤声明并管理一次性护肤副作用声明，并且主服务器（20）通过网络与接收器通信。 数据库（30）存储每个危险等级的产品信息，咨询信息，每个监视项目的得分，护肤副作用评分，护肤副作用声明比率和管理信息。 分析系统（40）包括基于每个监视项目的分数和咨询信息对护肤副作用声明进行评分的算法，基于咨询和产品信息计算护肤副作用声称比率的引擎，以及对 根据模糊逻辑从护肤副作用评分和护肤副作用索赔比率的危险水平。 相关部门（50）根据主服务器的危险等级接收报警类型的管理。
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公开(公告)号：KR1020070069625A
公开(公告)日：2007-07-03
申请号：KR1020050131954
申请日：2005-12-28
Applicant: (주)아모레퍼시픽
Abstract: A cosmetic composition containing the extract of Mentha Piperita for reducing skin irritation caused by retinoid is provided to inhibit expression of inflammation-causing materials such as ICAM-1 (intercellular adhesion molecule-1) and IL-1alpha(interleukin-1 alpha) factor. The cosmetic composition for reducing skin irritation and inflammation caused by retinoid contains 0.1-1 wt.% of the extract of Mentha Piperita which inhibits expression of IL-1alpha factor, and erythema and edema formation responses irritated by retinoid, wherein the retinoid is retinol, retinal or retinoic acid; and the Mentha Piperita extract contains 0.9-1.8 g/l of polyphenols having antioxidizing effects.
Abstract translation: 提供含有薄荷提取物的化妆品组合物，用于减少由类视黄醇引起的皮肤刺激，以抑制致炎物质如ICAM-1（细胞间粘附分子-1）和IL-1α（白细胞介素-1α）因子的表达。 用于减少由类视黄醇引起的皮肤刺激和炎症的化妆品组合物含有0.1-1重量％的抑制IL-1α因子表达的薄荷提取物，以及类视黄醇刺激的红斑和水肿形成反应，其中类视黄醇是视黄醇， 视网膜或视黄酸; 薄荷提取物含有0.9-1.8克/升的具有抗氧化作用的多酚。
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公开(公告)号：KR1020050080480A
公开(公告)日：2005-08-12
申请号：KR1020040008305
申请日：2004-02-09
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 피부자극 및 염증을 완화시키는 효능을 갖는 민감성 화장료 조성물에 관한 것으로, 보다 상세하게는 수박(Citrullus Vulgaris) 내피 추출물을 함유함으로써, 레티놀 및 자외선 자극에 대항하여 피부 세포에서 염증매개인자인 인터페론-γ에 의한 ICAM-1의 발현 및 IL-1α, TNF-α 및 IL-8의 생합성을 억제하는 것을 통해, 자극완화 기능 및 사이토카인(cytokine)의 생성 조절기능에 의해 민감성 피부를 개선하며 이들을 환경에 적응하도록 하는 효능이 뛰어난 민감성 피부용 화장료 조성물에 관한 것이다.
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