Abstract:
A screening method of anti-gray hair ingredient is provided to improve accuracy of screening, and reduce the time and expenses to be required for the screening, thereby efficiently preventing gray hair. The screening method of anti-gray hair ingredient comprises the steps of: treating the transformed cell line with the candidate anti-gray hair ingredient, and culturing the treated cell line in the culture medium; measuring the production amount of GLuc(Gaussia luciferase) gene existing in the culture medium; removing hairs from the back of vitiligo mouse and spreading the candidate anti-gray hair ingredient on the hair-removed back of mouse; and measuring the melanin amount in the new born hair from the back of vitiligo mouse, wherein the transformed cell line is produced by transforming a host cell line with an expression vector pMITF-GLuc containing microphtalmia-associated factor(MITF) promoter, GLuc gene, NeoR(neomycin resistant) gene and AmpR(ampicilin resistant) gene.
Abstract:
본 발명은 녹차다당체의 제조방법에 관한 것으로, 보다 상세하게는 a) 용매를 이용하여 녹차 분말에서 엽록소 및 저분자량의 폴리페놀을 제거하는 단계; b) 상기 a)단계의 녹차 잔사로부터 수용성 활성성분을 열수 추출하는 단계; 및 c) 상기 b)단계의 열수 추출물로부터 한외여과 및 에탄올 침전 반응으로 녹차다당체를 분리하는 단계를 포함하는 것을 특징으로 하는 녹차다당체의 제조방법에 관한 것이다. 본 발명에 따라 제조한 녹차다당체를 함유하는 화장료 조성물은 우수한 피부 미백, 보습 및 주름 개선 효과를 나타낸다.
Abstract:
본 발명은 백화고 유래의 에르고스테롤을 함유하는 피부 외용제 조성물에 관한 것으로서, 보다 상세하게는 백화고 추출물로부터 분리 정제하여 수득한 에르고스테롤인 3 β ,5 α ,9 α -트리하이드록시-(22 E ,24 R )-에르고스타-7,22-디엔-6-온을 함유함으로써 우수한 미백 효능을 나타내는 피부 외용제 조성물에 관한 것이다.
Abstract:
PURPOSE: A composition containing a mixture extract of Lycium chinense Miller and Pinus densiflora Siebold et Zuccarini for antiaging through activation of a retinoic acid receptor is provided to ensure excellent skin antiaging or anti-wrinkling. CONSTITUTION: A cosmetic composition for antiaging contains a mixture extract of Lycium chinense Miller and Pinus densiflora Siebold et Zuccarini as an active ingredient. The mixture extract contains 40-60 wt% of the Lycium chinense Miller extract and 40-60 wt% of the Pinus densiflora Siebold et Zuccarini extract. The composition activates a retinoic acid receptor. The composition also prevents wrinkles by suppressing collagenase expression.
Abstract translation:目的:提供含有枸杞子和松果松混合提取物的组合物,用于通过活化视黄酸受体进行抗衰老以确保优异的皮肤抗衰老或抗皱纹。 构成:用于抗衰老的化妆品组合物含有枸杞的混合物提取物和松果松(Siebold et Zuccarini)作为活性成分。 混合物提取物含有40-60重量%的枸杞提取物和40-60重量%的松属松属Siebold和Zuccarini提取物。 该组合物激活视黄酸受体。 该组合物还通过抑制胶原酶表达来防止皱纹。
Abstract:
PURPOSE: A composition for skin anti-aging is provided to suppress matrix metalloprotease activation without skin irritation. CONSTITUTION: A composition for skin anti-aging contains 0.01-20 weight% of compound of chemical formula 1, isomer or pharmaceutically acceptable salt thereof as an active ingredient. The composition is used for preventing or treating wrinkling and skin aging. The composition is a pharmaceutical composition or cosmetic composition. The pharmaceutical composition is manufactured in the form of lotion, ointment, gel, cream, patch or spray. The cosmetic composition is used in the form of essence, nutrition cream, massage cream, pack, gel, essence, eye cream, cleansing cream, cleansing foam, pack, and powder.