Abstract:
PURPOSE: An artificial eardrum using a silk protein and a method for manufacturing the same are provided to have strengths in bio compatibility and transparency. CONSTITUTION: An artificial eardrum using a silk protein comprises a silk film shape by desalinating and drying silk protein or silk protein compound solution obtained after removing ceracin from cocoons or fibroin Silk protein or silk protein compound solution are dissolved using chaotropic salt or one compound of bromination lithium, lithium chloride, zinc chloride, or calcium chloride. At least one additive of gelatin, collagen, chitosan, alginic acid, hyaluronic acid, pluronic 127 or PEG is added to the silk film.
Abstract:
A composition for preventing and treating osteoporosis comprising silk peptide as an active ingredient is provided to suppress the differentiation of osteoclast by using natural protein. A composition for preventing and treating osteoporosis comprises silk peptide as an active ingredient. The silk peptide is an acid of silk or hydrolysate of enzyme. The silk peptide is the pyrolysate of cocoon containing sericin. An amino acid composition of the silk peptide are 80 weight% or greater based on the total content of glycine 40-45 weight%, alanine 20-30 weight% and serine 10-20 weight%.
Abstract:
A simple purifying method of bee venom is provided to minimize the change of bee venom ingredients in case that the bee venom is stored for long time and enable the continuous supply of bee venom. Therefore, the purified bee venom can be used for the development of food and medical supplies including bee venom as the ingredients. A method for purifying the bee venom collected from a glass collection board of a bee venom collecting apparatus comprises the steps of: a first process for dissolving the collected bee venom in a thirdly sterilized distilled water for 5~15min, wherein the weight ratio of the bee venom and the distilled water is 1:45~55; a second process for centrifuging 300g of the solution obtained from the first process at 4°C for 5~15min; a third process for filtering out supernatant from the centrifuged solution by filter paper having a pore size of 8mum, or by a vacuum pump; and a fourth process for drying the filtrate frozen at -65~75°C.
Abstract:
PURPOSE: Compositions for preventing or treating brain neuronal diseases and improving recognition function are provided, thereby effectively preventing or treating brain neuronal diseases with less of side-effects. CONSTITUTION: The composition for preventing or treating brain neuronal diseases comprises (a) a pharmaceutically effective amount of silk peptide produced by decomposition of silk protein; and (b) pharmaceutically acceptable carriers, wherein the silk protein is silk sericin or silk fibroin; the decomposition of silk protein is carried out by using calcium solution such as calcium chloride, acid hydrolysis, protein decomposing enzyme such as thermoase, flavourzyme, sumizyme, protamex and protin and a combination thereof; and the average molecular weight of the silk peptide is 300 to 100,000 dalton. The composition for improving recognition function comprises (a) a pharmaceutically effective amount of silk peptide produced by decomposition of silk protein; and (b) pharmaceutically acceptable carriers.