Abstract:
The present invention relates to an anisotropic protein nanostructure by spontaneous structure transformation and a method for preparing the same, and more particularly, to a method for preparing an anisotropic protein nanostructure retaining physicochemical demarcation and stimuli-responsiveness from a monoblock polymer including a block having stimuli-responsiveness and enabling chemical cross-linking or a diblock copolymer elastin-like polypeptide (ELP) including a block having stimuli-responsiveness and enabling chemical cross-linking and a block enabling chemical uncross-linking by using spontaneous structure transformation, an anisotropic protein nanostructure prepared by the method, an anisotropic nanoparticle structure in which the anisotropic protein nanostructure is spontaneously structurally transformed in an aqueous solution, and a use of the anisotropic protein nanostructure. The anisotropic protein nanostructure of the present invention retains physicochemical demarcation and has stimuli-responsiveness, and thus is useful in drug carriers, bio-imaging, bio-sensing, and bio-medical nano-devices.