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公开(公告)号：JP2010125147A
公开(公告)日：2010-06-10
申请号：JP2008304360
申请日：2008-11-28
Applicant: Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
Inventor： MIZUNO TOSHIHIKO , MIWA MITSUHARU , YAMASHITA YUTAKA , SHIKAYAMA TAKAHIRO , WATANABE ATSUSHI
IPC: A61B5/1455
Abstract: PROBLEM TO BE SOLVED: To precisely and simultaneously measure information in the blood of a living body and the physiological index of an autonomic nerve system.
SOLUTION: A biometric instrument 1 includes: an LED part 11 for allowing light S
735 and light S
850 , which have mutually different center wavelengths and are not simultaneously made incident, to be made incident, so that the incident period of the light S
850 becomes shorter than the incident period of the light S
735 ; a photodiode 13 for generating a digital signal AD
735 and a digital signal AD
850 respectively corresponding to the light S
735 and the light S
850 , and outputting the digital signal AD
735 and the digital signal AD
850 ; and a calculation part 31 for calculating changes in the concentrations of oxyhemoglobin and deoxyhemoglobin, based on the digital signal AD
735 and the digital signal AD
850 , and calculating pulse wave data, based on the digital signal AD
850 .
COPYRIGHT: (C)2010,JPO&INPITAbstract translation: 要解决的问题：精确并同时测量生物体血液中的信息和自主神经系统的生理指标。 生物测定仪1包括：用于允许具有相互不同的中心波长并且不同时形成的光S
735 和光S 850 的LED部分11 事件发生，使得光S 850 的入射时间变得比光S 735 的入射时间短。 分别对应于光S 735 和光S 735 和数字信号AD 850 的光电二极管13 > 850 ，并输出数字信号AD 735 和数字信号AD 850 ; 以及计算部31，用于根据数字信号AD 735 和数字信号AD 850 计算氧合血红蛋白和脱氧血红蛋白的浓度变化，并计算脉搏波数据， 基于数字信号AD 850 。 版权所有（C）2010，JPO＆INPIT -
公开(公告)号：JPH0682096B2
公开(公告)日：1994-10-19
申请号：JP32210590
申请日：1990-11-26
Applicant: HAMAMATSU PHOTONICS KK
Inventor： ODA MOTOKI , YAMASHITA YUTAKA , OOTA KAZUYOSHI , TAMURA MAMORU , NISHIMURA GORO
IPC: G01N21/49 , A61B5/145 , A61B5/1455 , A61B5/14
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公开(公告)号：JPH02151735A
公开(公告)日：1990-06-11
申请号：JP30731188
申请日：1988-12-05
Applicant: HAMAMATSU PHOTONICS KK
Inventor： YAMASHITA YUTAKA , TSUCHIYA KOJI , OTA KAZUYOSHI
Abstract: PURPOSE:To protect a light detector during a period when strong light of certain definite quantity or more is incident on the side of the detector and to allow light to be incident at the point of time when said strong light becomes less than the definite quantity by providing a photodetector, a control circuit and a light deflecting element. CONSTITUTION:When an object 3 to be detected enters between optical fibers 2, 4, transmitted light toward a light detector 5 suddenly becomes weak to be sent to a photodetector 11 through a beam splitter 10. When the quantity of the light received by the element 11 becomes a definite value or less, the control signal of a control circuit 2 is not outputted. Whereupon, a light deflecting element 9 performs diffraction action on the basis of the signal subjected to defraction control of a drive circuit 13 and diffracts the greater part of the light from a light source 1 to allow said light to be incident to one optical fiber 2. The light is transmitted through the object 3 to be detected through said one optical fiber 2 to be received by other optical fiber 4 and further sent to the detector 5. The bleeder 14 of the detector 5 is released from inverse bias when the control signal from the circuit 12 is lost and the detector 5 returns to usual sensitivity and the data of the object 3 to be detected is obtained by the detector 5.
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公开(公告)号：JPS6353482A
公开(公告)日：1988-03-07
申请号：JP19868586
申请日：1986-08-25
Applicant: HAMAMATSU PHOTONICS KK
Inventor： TSUCHIYA KOJI , HAYAKAWA TAKESHI , OSUGA SHINJI , YAMASHITA YUTAKA
Abstract: PURPOSE:To enable a stable determination to be performed even in a consumer appliance field wherein no calibrating radiation source can be handled by performing an energy calibration by using radiation emitted from K contained in a potassium compound in a gamma ray dosimeter using a scintillator. CONSTITUTION:A dosimeter is composed of a potassium compound 1 for calibration, a scintillator 2, a photomultiplier 3, charge quantity detector 4, an integrating memory 5, an arithmetic unit 6, an energy distribution memory 7, an energy distribution and dosage display unit 8 and an input unit 9. Since a sensitivity in conversion to a charge quantity is changed by a change in temperature or the like in the scintillator 2 and the photomultiplier 3, a calibration is conducted as follows: gamma rays from a K isotope contained in natural potassium by 0.01% are detected, the peak value of gamma rays that appear in the memory 5 is obtained and gamma ray energy and the charge quantity are calibrated by using the peak value of gamma rays. To do this, a cursor is set to a peak position displayed on the display unit 8 and a calibrating signal is inputted from the input unit 9 whereby a charge quantity scale is transformed to an energy scale.
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公开(公告)号：JP2014137338A
公开(公告)日：2014-07-28
申请号：JP2013007418
申请日：2013-01-18
Applicant: Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
Inventor： UEDA YUKIO , YAMASHITA YUTAKA
Abstract: PROBLEM TO BE SOLVED: To provide a cross-section image measuring device and a cross-section image measuring method capable of using both of an ultrasonic image measurement and an optical measurement with a simple configuration.SOLUTION: A cross-section image measuring device 1A is constituted of an ultrasonic image measuring device 10 having an ultrasonic probe 11 and for obtaining ultrasonic image data of a first cross-section of a measurement object S, a time resolution measuring device 15 having an optical incident probe 16 and a light emission probe 17 and for obtaining time resolution waveform data of emitted light propagated inside the measurement object S by pulse measuring light, and a measurement processing device 30 for performing data processing with respect to a cross-section measurement. The measurement processing device 30 includes: an ultrasonic image generation unit 31 for generating an ultrasonic image; an optical path image generation unit 32 for generating an optical path distribution image; and a cross-section image generation unit 35 for generating a synthesized cross-section image of the ultrasonic image and the optical path distribution image.
Abstract translation: 要解决的问题：提供一种能够以简单的结构使用超声波图像测量和光学测量两者的横截面图像测量装置和横截面图像测量方法。解决方案：横截面图像测量装置1A 由具有超声波探头11的超声波图像测量装置10构成，并且用于获得测量对象S的第一横截面的超声波图像数据;时间分辨率测量装置15，具有光入射探针16和发光探针17 并且用于通过脉冲测量光获得在测量对象S内传播的发射光的时间分辨率波形数据;以及用于对横截面测量进行数据处理的测量处理装置30。 测量处理装置30包括：超声波图像生成单元31，用于生成超声波图像; 用于产生光路分布图像的光路图像生成单元32; 以及用于产生超声波图像和光路分布图像的合成截面图像的截面图像生成单元35。
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Patent Agency Ranking
公开(公告)号：JP2009189726A
公开(公告)日：2009-08-27
申请号：JP2008036211
申请日：2008-02-18
Applicant: Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
Inventor： SUZUKI TOSHIHIKO , YAMASHITA YUTAKA , OMAE ETSUKO , YAMASHITA DAISUKE , YOSHIMOTO KENJI
IPC: A61B10/00
Abstract: PROBLEM TO BE SOLVED: To provide a mammographic apparatus capable of visually recognizing the position of a breast from an external part so as to reliably insert the breast into a measurement part, and raising light tightness in the measurement part in performing measurement.
SOLUTION: The mammographic apparatus 1 obtains the information on the inside of a breast B by irradiating the breast B of a subject A with light and detecting the diffused light. The apparatus includes: a bed 10 which supports the subject A in a prone position and has an opening where the breast B is put-through; a vessel 3 arranged in the lower part of the opening and enclosing the breast B; and the measurement part 2 which is arranged to face the inner side of the vessel in order to radiate and detect the light and has a plurality of optical fibers 11. The measurement part 2 is configured to face the bed 10, to move vertically, and to close by light tightness the opening by being brought into contact with the bed 10 at the upper limit position.
COPYRIGHT: (C)2009,JPO&INPITAbstract translation: 要解决的问题：提供能够从外部视觉识别乳房位置的乳房照相装置，以便可靠地将乳房插入到测量部件中，并且在进行测量时提高测量部件的光密性。 解决方案：乳房X线照相设备1通过用光照射被检体A的乳房B并检测漫射光来获得乳房B内部的信息。 该装置包括：床10，其在俯卧位置支撑被检体A，并且具有胸部B穿过的开口; 布置在开口的下部并包围乳房B的容器3; 以及测量部件2，其布置成面对容器的内侧，以便辐射和检测光并具有多个光纤11.测量部件2被配置为面向床10以垂直移动，并且 通过在上限位置与床10接触而使开口闭合闭合。 版权所有（C）2009，JPO＆INPIT
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公开(公告)号：JPH1137850A
公开(公告)日：1999-02-12
申请号：JP19589897
申请日：1997-07-22
Applicant: HAMAMATSU PHOTONICS KK
Inventor： URAGAMI TSUNEYUKI , ANDO TARO , YAMASHITA YUTAKA
Abstract: PROBLEM TO BE SOLVED: To provide a time-correlated photon counting type light waveform measuring apparatus of a simple structure and a high counting rate capable of performing high-precision measurement. SOLUTION: Photons of a light to be measured having a specified cycle period T outputted from a light source 1 to be measured strike a photo detector 2, and are converted into an electric pulse. This electric pulse is sent via a preamplifier to a number-of-photons analyzer 4 and a timing pick-up circuit 5 respectively. The number-of-photons analyzer 4 decides the number of photons detected in a period, and the timing pick-up circuit 5 extracts an electric pulse corresponding to the first photon in the period. A photon detection frequency analyzing unit 6 finds an arrival time of a photon only when the number of photons is one, on the basis of these signals. A waveform outputting apparatus 6 adds up the number of times of photon detection in each time range of a fractionalized period, and finds the frequency of generation of photons. This generation frequency corresponds to the waveform of light to be measured.
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公开(公告)号：JPH09126878A
公开(公告)日：1997-05-16
申请号：JP30046495
申请日：1995-10-26
Applicant: AGENCY IND SCIENCE TECHN , HAMAMATSU PHOTONICS KK
Inventor： YAMADA YUKIO , ARAKI RYUICHIRO , YAMASHITA YUTAKA
Abstract: PROBLEM TO BE SOLVED: To provide a method for determining an optical constant in even such a small specimen that cannot be considered to be a semi-infinite or infinite flat plate or has an optical constant with distribution, concerning the light propagation. SOLUTION: The time changes of outputted light intensity in many combinations of equivalent scattering coefficient μ's , and absorption coefficient μs of a scattering object are calculated by the Monte Carlo method in advance. Next, a pulse light is allowed to enter a specimen and the time change of the outputted light intensity is measured. Then, when the measured time change thereof is coincided with or almost the same as either of the calculated time changes thereof, the equivalent scattering coefficient μ's and absorption coefficient μs are considered to be the equivalent coefficient μ's and absorption coefficient μs of the specimen.
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公开(公告)号：JPH06281822A
公开(公告)日：1994-10-07
申请号：JP27995892
申请日：1992-10-19
Applicant: HAMAMATSU PHOTONICS KK , MIYAGAWA ATSUO
Inventor： MIYAGAWA ATSUO , HIRANO MASAHIKO , YAMASHITA YUTAKA , HIRUMA TERUO
Abstract: PURPOSE:To realize the measurement in the inside of a living body without inflicting an injury on the living boy by providing a prescribed optical fiber bundle, and an objective lens for magnifying a optical image of an object to be measured. CONSTITUTION:One light input/output end 7b of a optical fiber bundle 7 fitted to an optical mechanism A is inserted into a deep part in a living body by a user by the knack of inserting an injection needle, and the tip face of its light input/output end 7b is brought into contact with or opposed to a part B to be observed of a living body tissue and a cell, etc. In such a state, when the measurement is started, light which is made incident through a light source 5 and an optical filter part 6, a dichroic mirror 2 and an objective lens 1 is cast as an illuminating light on the object B to be measured from the tip face of the light input/output end 7b, and an obtained optical image is transferred to the tip face of the other light input/output end 7c opposed to the objective lens 1. Subsequently, by the objective lens 1, the optical image of the tip face of the light input/output end 7c is magnified and transmitted to the dichroic mirror 2, and also, transmitted to the image pickup face of a two-dimensional image sensor 4 through an interference filter 3, and reproduced by a monitor 10.
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公开(公告)号：JPH0412736A
公开(公告)日：1992-01-17
申请号：JP11653390
申请日：1990-05-02
Applicant: HAMAMATSU PHOTONICS KK
Inventor： YAMASHITA YUTAKA , OTA KAZUYOSHI , ODA MOTOKI , ITO TOSHIAKI , KYOMASU MIKIO
IPC: A61B5/145 , A61B5/1455
Abstract: PURPOSE:To decrease the errors by a difference in reflected light measuring parts and the errors by the color, etc., of the skin by providing the measuring parts at the plural points varying in the distance from a light source and computing the change rate of an exponent part by regarding the attenuation of the intensity of the reflected light with the distance from a light incident position as an exponential function. CONSTITUTION:This instrument is disposed with a 1st light receiving part 22 and a 2nd light receiving part 24 at the two points varying in the distance from the light source 20 provided with two pieces of light emitting diodes 20A, 20B which generate the light of different wavelengths in a housing 12 for housing main constituting parts. The quantity of the reflected light received by the two light receiving parts 22, 24 is considered to attenuate exponential-functionally in accordance with Lambert-Beer law with the distance and the change rate of the exponential part thereof is computed by a microcomputer 28. The errors by the movement of the measuring parts 22, 24 and the contact state of the light source 20 and the detector with the measuring parts 22, 24 are, therefore, decreased. Since the measurement is made by selectively making >=2 kinds of the light rays of the different wavelengths incident on a living body, the errors by the difference in, for example, the color of the skin, etc., are prevented.
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